| Enhancing anti-interference ability of molecularly imprinted ratiometric fluorescence sensor via differential strategy demonstrated by the detection of bovine hemoglobin | |
Wang, Jiangru1; Chen, Xiaolan1 ; Wang, Xiaoyan2; Kang, Qi1; Shen, Dazhong1; Chen, Lingxin3
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| 发表期刊 | SENSORS AND ACTUATORS B-CHEMICAL
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| 2020-11-01 | |
| 卷号 | 322页码:9 |
| 关键词 | Molecular imprinting Ratiometric fluorescence Differential measurement Smartphone Bovine hemoglobin |
| DOI | 10.1016/j.snb.2020.128581 |
| 通讯作者 | Shen, Dazhong(dzshen@sdnu.edu.cn) ; Chen, Lingxin() |
| 英文摘要 | The non-specific adsorption of interferents onto the outside surface of molecularly imprinted polymers (MIPs) particles is disadvantageous for selective determination of the template molecules. Based on the fact that the responses of non-imprinted polymers (NIPs) and MIPs particles to non-template molecules are similar, the anti-interference ability of MIPs sensor can be much improved via differential strategy, demonstrated by bovine hemoglobin (BHb) determination. The MIPs for BHb were prepared via surface imprinting and sol-gel process, with graphene quantum dots@SiO2/CdTe quantum dots (GODs@SiO2/CdTe QDs) for ratiometric fluorescence measurements. By using a weight factor of 1.283 to compensate the lower specific surface area in NIPs particles, the differential ratiometric fluorescence signals between MIPs and NIPs channels to 2.00 mu M ovalbumin and phycocyanin are equivalent to BHb at the concentration of 0.025 and 0.014 mu M, which are only about 11 % and 5.8 % of the interference level in the normal ratiometric fluorescence method, respectively. The differential ratiometric fluorescence measurement was also performed in a smartphone-based device for field analysis of BHb in urine samples, with the linear range of 0.05-4 mu M and the detection limit of 13 nM. |
| 资助机构 | National Natural Science Foundation of China ; Natural Science Foundation of Shandong Province of China ; Taishan Scholar Project Special Fund |
| 收录类别 | SCI |
| 语种 | 英语 |
| 关键词[WOS] | SELECTIVE RECOGNITION ; SENSITIVE DETECTION ; QUANTUM DOTS ; SMARTPHONE ; POLYMERS ; NANOPARTICLES ; PERFORMANCE |
| 研究领域[WOS] | Chemistry ; Electrochemistry ; Instruments & Instrumentation |
| WOS记录号 | WOS:000573296800001 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.yic.ac.cn/handle/133337/28497 |
| 专题 | 中国科学院海岸带环境过程与生态修复重点实验室_海岸带环境工程技术研究与发展中心 中国科学院海岸带环境过程与生态修复重点实验室 |
| 通讯作者 | Shen, Dazhong; Chen, Lingxin |
| 作者单位 | 1.Shandong Normal Univ, Coll Chem Chem Engn & Mat Sci, Key Lab Mol & Nano Probes, Minist Educ, Jinan 250014, Peoples R China 2.Binzhou Med Univ, Sch Pharm, Yantai 264003, Peoples R China 3.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Jiangru,Chen, Xiaolan,Wang, Xiaoyan,et al. Enhancing anti-interference ability of molecularly imprinted ratiometric fluorescence sensor via differential strategy demonstrated by the detection of bovine hemoglobin[J]. SENSORS AND ACTUATORS B-CHEMICAL,2020,322:9. |
| APA | Wang, Jiangru,Chen, Xiaolan,Wang, Xiaoyan,Kang, Qi,Shen, Dazhong,&Chen, Lingxin.(2020).Enhancing anti-interference ability of molecularly imprinted ratiometric fluorescence sensor via differential strategy demonstrated by the detection of bovine hemoglobin.SENSORS AND ACTUATORS B-CHEMICAL,322,9. |
| MLA | Wang, Jiangru,et al."Enhancing anti-interference ability of molecularly imprinted ratiometric fluorescence sensor via differential strategy demonstrated by the detection of bovine hemoglobin".SENSORS AND ACTUATORS B-CHEMICAL 322(2020):9. |
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