Occurrence and distribution of antibiotic resistance genes in sediments in a semi-enclosed continental shelf sea
Zhang, Yuxuan; Lu, Jian; Wu, Jun; Wang, Jianhua; Lin, Yichen
Source PublicationSCIENCE OF THE TOTAL ENVIRONMENT
2020-06-10
Volume720Pages:137712
KeywordRIVER CHINA ABUNDANCE POLLUTION IMPACTS ESTUARY WATER FATE ARGS
MOST Discipline CatalogueEnvironmental Sciences
DOI10.1016/j.scitotenv.2020.137712
Contribution Rank[Zhang, Yuxuan; Lu, Jian; Wang, Jianhua; Lin, Yichen] Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Shandong Key Lab Coastal Environm Proc,YICCAS, Yantai 264003, Shandong, Peoples R China; [Zhang, Yuxuan; Lu, Jian; Lin, Yichen] Univ Chinese Acad Sci, Beijing 100049, Peoples R China; [Lu, Jian] Chinese Acad Sci, Ctr Ocean Megasci, 7 Nanhai Rd, Qingdao 266071, Peoples R China; [Wu, Jun] Ludong Univ, Sch Resources & Environm Engn, Yantai 264025, Shandong, Peoples R China
Department海岸带环境过程实验室
AbstractExtensive and improper overuse of antibiotics resulted in the prevalence of antibiotic resistance genes (ARGs). As the typical semi-enclosed continental shelf sea, the Bohai Sea has been considered as one of the most polluted marine areas in China. However, no comprehensive investigation on the spatial distribution of ARGs in sediments from the Bohai Sea has been reported. A large-scale sampling was performed in the Bohai Sea areas. The abundances of ARGs (6 classes, 29 ARG subtypes), class 1 integron-integrase gene (intI1), hmt-DNA and 16S rRNA gene were evaluated. IntI1 was detected with higher abundances in coastal areas ranging from 2.8 x 10(5) to 2.5 x 10(8) copies/g. The total ARGs abundances varied over 3 orders of magnitude in different sampling sites with the maximum at 4.9 x 10(8) copies/g. Sulfonamides resistance genes were ubiquitous and abundant with the abundances ranging from 5.7 x 10(4) to 1.8 x 10(7) copies/g, and quinolones resistance genes varied greatly in different samples. The contour map demonstrated that ARGs were more abundant in the Laizhou Bay, the south of Bohai Bay and the eastern of central sea basin. Most of the target ARG subtypes were detected with 100% detection frequencies. The genes of sul1, sul2 and tetX were detected with both higher absolute and relative abundance, while the abundance of beta-lactams ARG subtypes was lower. Principal component analysis (PCA) and redundancy analysis (RDA) indicated that no significant differences in the ARGs abundance existed in different samples, and the sediment qualities played important roles in the distribution of ARGs. Bacterial communities were investigated and 768 strong and significant connections between ARGs and bacteria were identified. The possible hosts of ARGs were revealed by network analysis with higher relative abundance in coastal areas than the sea. (C) 2020 Elsevier B.V. All rights reserved.
SubtypeArticle
Indexed BySCI
Language英语
WOS KeywordRIVER ; CHINA ; ABUNDANCE ; POLLUTION ; IMPACTS ; ESTUARY ; WATER ; FATE ; ARGS
WOS IDWOS:000525736600104
Funding OrganizationNational Natural Science Foundation of ChinaNational Natural Science Foundation of China [41877131] ; Taishan Scholars Project of Shandong Province [tsqn201812116] ; One Hundred Talents Program of Chinese Academy of SciencesChinese Academy of Sciences [Y629041021] ; Science and Technology Service Network Initiative of the Chinese Academy of Sciences [KFJ-STS-QYZX-114] ; Two Hundred Talents Plan of Yantai [Y739011021] ; Youth Innovation Team Project for Talent Introduction and Cultivation in Universities of Shandong Province
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Document Type期刊论文
Identifierhttp://ir.yic.ac.cn/handle/133337/25020
Collection中科院海岸带环境过程与生态修复重点实验室_海岸带环境过程实验室
Affiliation1.Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Shandong Key Lab Coastal Environm Proc,YICCAS, Yantai 264003, Shandong, Peoples R China;
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China;
3.Chinese Acad Sci, Ctr Ocean Megasci, 7 Nanhai Rd, Qingdao 266071, Peoples R China;
4.Ludong Univ, Sch Resources & Environm Engn, Yantai 264025, Shandong, Peoples R China
Recommended Citation
GB/T 7714
Zhang, Yuxuan,Lu, Jian,Wu, Jun,et al. Occurrence and distribution of antibiotic resistance genes in sediments in a semi-enclosed continental shelf sea[J]. SCIENCE OF THE TOTAL ENVIRONMENT,2020,720:137712.
APA Zhang, Yuxuan,Lu, Jian,Wu, Jun,Wang, Jianhua,&Lin, Yichen.(2020).Occurrence and distribution of antibiotic resistance genes in sediments in a semi-enclosed continental shelf sea.SCIENCE OF THE TOTAL ENVIRONMENT,720,137712.
MLA Zhang, Yuxuan,et al."Occurrence and distribution of antibiotic resistance genes in sediments in a semi-enclosed continental shelf sea".SCIENCE OF THE TOTAL ENVIRONMENT 720(2020):137712.
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