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Novel monodisperse molecularly imprinted shell for estradiol based on surface imprinted hollow vinyl-SiO2 particles
Wang, Xiaoyan1,2,3; Kang, Qi1; Shen, Dazhong1; Zhang, Zhong2,4; Li, Jinhua2; Chen, Lingxin2; Shen, DZ (reprint author), Shandong Normal Univ, Coll Chem Chem Engn & Mat Sci, Minist Educ China, Key Lab Mol & Nanomat Probes, Jinan 250014, Peoples R China. dzshen@sdnu.edu.cn; lxchen@yic.ac.cn
2014-06-15
Source PublicationTALANTA
ISSN0039-9140
Volume124Pages:7-13
Contribution Rank[Wang, Xiaoyan; Kang, Qi; Shen, Dazhong] Shandong Normal Univ, Coll Chem Chem Engn & Mat Sci, Minist Educ China, Key Lab Mol & Nanomat Probes, Jinan 250014, Peoples R China; [Wang, Xiaoyan; Zhang, Zhong; Li, Jinhua; Chen, Lingxin] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China; [Wang, Xiaoyan] Binzhou Med Univ, Yantai 264003, Peoples R China; [Zhang, Zhong] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
AbstractA novel monodisperse molecularly imprinted shell was prepared based on surface imprinted hollow vinyl-SiO2 particles and applied to selective recognition and adsorption of estradiol (E-2). This method was carried out by introducing vinyltriethoxysilane to the surface of polystyrene (PS) spheres by a simple one-step modification, followed by dissolution to remove the PS cores, and then by copolymerization of functional monomers via surface imprinted on the hollow vinyl-SiO2 particles to prepare uniform E-2-imprinted shells. Two interesting characteristics were found: first, the obtained hollow molecularly imprinted polymer shells (H-MIPs) had highly monodispersity, uniform spherical shape with a shell thickness of about 40 nm: and then, the method was simple, easy to operate by directing coating of a uniform shell on hollow particles via surface imprinting. The resultant H-MIPs demonstrated improvements in imprinting factor and binding kinetics, owing to the high selectivity to template molecules, surface imprinting technique and hollow porous structure. Furthermore, satisfactory recoveries of 97.0 and 94.8% with respective precisions of 2.5 and 2.7% were achieved by one-step extraction when H-MIPs were used for the preconcentration and selective separation of estradiol in milk samples at two spiked levels. The simple, effective H-MIPs based strategy provided new insights into the formation of various functionalized coating layers on different kinds of support materials with versatile potential applications. (C) 2014 Elsevier BM. All rights reserved.; A novel monodisperse molecularly imprinted shell was prepared based on surface imprinted hollow vinyl-SiO2 particles and applied to selective recognition and adsorption of estradiol (E-2). This method was carried out by introducing vinyltriethoxysilane to the surface of polystyrene (PS) spheres by a simple one-step modification, followed by dissolution to remove the PS cores, and then by copolymerization of functional monomers via surface imprinted on the hollow vinyl-SiO2 particles to prepare uniform E-2-imprinted shells. Two interesting characteristics were found: first, the obtained hollow molecularly imprinted polymer shells (H-MIPs) had highly monodispersity, uniform spherical shape with a shell thickness of about 40 nm: and then, the method was simple, easy to operate by directing coating of a uniform shell on hollow particles via surface imprinting. The resultant H-MIPs demonstrated improvements in imprinting factor and binding kinetics, owing to the high selectivity to template molecules, surface imprinting technique and hollow porous structure. Furthermore, satisfactory recoveries of 97.0 and 94.8% with respective precisions of 2.5 and 2.7% were achieved by one-step extraction when H-MIPs were used for the preconcentration and selective separation of estradiol in milk samples at two spiked levels. The simple, effective H-MIPs based strategy provided new insights into the formation of various functionalized coating layers on different kinds of support materials with versatile potential applications. (C) 2014 Elsevier BM. All rights reserved.
KeywordEstradiol Molecularly Imprinted Polymer Surface Imprinting Hollow Vinyl-sio2 Particle Polystyrene
Department中科院海岸带环境过程与生态修复重点实验室
Subject AreaChemistry, Analytical
DOI10.1016/j.talanta.2014.02.040
Funding OrganizationChemistry
Indexed BySCI
WOS KeywordSOLID-PHASE EXTRACTION ; SUBMICROMETER PARTICLES ; PROTEIN RECOGNITION ; SILICA SPHERES ; POLYMERS ; NANOPARTICLES ; FABRICATION ; SAMPLES
SubtypeArticle
Language英语
WOS Research AreaChemistry
WOS IDWOS:000336114900002
Citation statistics
Cited Times:44[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.yic.ac.cn/handle/133337/8737
Collection中科院海岸带环境过程与生态修复重点实验室
Corresponding AuthorShen, DZ (reprint author), Shandong Normal Univ, Coll Chem Chem Engn & Mat Sci, Minist Educ China, Key Lab Mol & Nanomat Probes, Jinan 250014, Peoples R China. dzshen@sdnu.edu.cn; lxchen@yic.ac.cn
Affiliation1.Shandong Normal Univ, Coll Chem Chem Engn & Mat Sci, Minist Educ China, Key Lab Mol & Nanomat Probes, Jinan 250014, Peoples R China
2.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China
3.Binzhou Med Univ, Yantai 264003, Peoples R China
4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
First Author AffilicationYantai Institute of Coastal Zone Research, Chinese Academy of Sciences
Recommended Citation
GB/T 7714
Wang, Xiaoyan,Kang, Qi,Shen, Dazhong,et al. Novel monodisperse molecularly imprinted shell for estradiol based on surface imprinted hollow vinyl-SiO2 particles[J]. TALANTA,2014,124:7-13.
APA Wang, Xiaoyan.,Kang, Qi.,Shen, Dazhong.,Zhang, Zhong.,Li, Jinhua.,...&lxchen@yic.ac.cn.(2014).Novel monodisperse molecularly imprinted shell for estradiol based on surface imprinted hollow vinyl-SiO2 particles.TALANTA,124,7-13.
MLA Wang, Xiaoyan,et al."Novel monodisperse molecularly imprinted shell for estradiol based on surface imprinted hollow vinyl-SiO2 particles".TALANTA 124(2014):7-13.
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