Novel monodisperse molecularly imprinted shell for estradiol based on surface imprinted hollow vinyl-SiO2 particles

doi:10.1016/j.talanta.2014.02.040

	Novel monodisperse molecularly imprinted shell for estradiol based on surface imprinted hollow vinyl-SiO2 particles
	Wang, Xiaoyan 1,2,3; Kang, Qi 1; Shen, Dazhong 1; Zhang, Zhong 2,4; Li, Jinhua2 ; Chen, Lingxin2 ; Shen, DZ (reprint author), Shandong Normal Univ, Coll Chem Chem Engn & Mat Sci, Minist Educ China, Key Lab Mol & Nanomat Probes, Jinan 250014, Peoples R China. dzshen@sdnu.edu.cn ; lxchen@yic.ac.cn
发表期刊	TALANTA
ISSN	0039-9140
	2014-06-15
卷号	124 页码:7-13
关键词	Estradiol Molecularly Imprinted Polymer Surface Imprinting Hollow Vinyl-sio2 Particle Polystyrene
DOI	10.1016/j.talanta.2014.02.040
产权排序	[Wang, Xiaoyan; Kang, Qi; Shen, Dazhong] Shandong Normal Univ, Coll Chem Chem Engn & Mat Sci, Minist Educ China, Key Lab Mol & Nanomat Probes, Jinan 250014, Peoples R China; [Wang, Xiaoyan; Zhang, Zhong; Li, Jinhua; Chen, Lingxin] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China; [Wang, Xiaoyan] Binzhou Med Univ, Yantai 264003, Peoples R China; [Zhang, Zhong] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
作者部门	中科院海岸带环境过程与生态修复重点实验室
英文摘要	A novel monodisperse molecularly imprinted shell was prepared based on surface imprinted hollow vinyl-SiO2 particles and applied to selective recognition and adsorption of estradiol (E-2). This method was carried out by introducing vinyltriethoxysilane to the surface of polystyrene (PS) spheres by a simple one-step modification, followed by dissolution to remove the PS cores, and then by copolymerization of functional monomers via surface imprinted on the hollow vinyl-SiO2 particles to prepare uniform E-2-imprinted shells. Two interesting characteristics were found: first, the obtained hollow molecularly imprinted polymer shells (H-MIPs) had highly monodispersity, uniform spherical shape with a shell thickness of about 40 nm: and then, the method was simple, easy to operate by directing coating of a uniform shell on hollow particles via surface imprinting. The resultant H-MIPs demonstrated improvements in imprinting factor and binding kinetics, owing to the high selectivity to template molecules, surface imprinting technique and hollow porous structure. Furthermore, satisfactory recoveries of 97.0 and 94.8% with respective precisions of 2.5 and 2.7% were achieved by one-step extraction when H-MIPs were used for the preconcentration and selective separation of estradiol in milk samples at two spiked levels. The simple, effective H-MIPs based strategy provided new insights into the formation of various functionalized coating layers on different kinds of support materials with versatile potential applications. (C) 2014 Elsevier BM. All rights reserved.; A novel monodisperse molecularly imprinted shell was prepared based on surface imprinted hollow vinyl-SiO2 particles and applied to selective recognition and adsorption of estradiol (E-2). This method was carried out by introducing vinyltriethoxysilane to the surface of polystyrene (PS) spheres by a simple one-step modification, followed by dissolution to remove the PS cores, and then by copolymerization of functional monomers via surface imprinted on the hollow vinyl-SiO2 particles to prepare uniform E-2-imprinted shells. Two interesting characteristics were found: first, the obtained hollow molecularly imprinted polymer shells (H-MIPs) had highly monodispersity, uniform spherical shape with a shell thickness of about 40 nm: and then, the method was simple, easy to operate by directing coating of a uniform shell on hollow particles via surface imprinting. The resultant H-MIPs demonstrated improvements in imprinting factor and binding kinetics, owing to the high selectivity to template molecules, surface imprinting technique and hollow porous structure. Furthermore, satisfactory recoveries of 97.0 and 94.8% with respective precisions of 2.5 and 2.7% were achieved by one-step extraction when H-MIPs were used for the preconcentration and selective separation of estradiol in milk samples at two spiked levels. The simple, effective H-MIPs based strategy provided new insights into the formation of various functionalized coating layers on different kinds of support materials with versatile potential applications. (C) 2014 Elsevier BM. All rights reserved.
文章类型	Article
资助机构	Chemistry
收录类别	SCI
语种	英语
关键词[WOS]	SOLID-PHASE EXTRACTION ; SUBMICROMETER PARTICLES ; PROTEIN RECOGNITION ; SILICA SPHERES ; POLYMERS ; NANOPARTICLES ; FABRICATION ; SAMPLES
研究领域[WOS]	Chemistry
WOS记录号	WOS:000336114900002
引用统计	被引频次：61[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.yic.ac.cn/handle/133337/8737
专题	中国科学院海岸带环境过程与生态修复重点实验室
通讯作者	Shen, DZ (reprint author), Shandong Normal Univ, Coll Chem Chem Engn & Mat Sci, Minist Educ China, Key Lab Mol & Nanomat Probes, Jinan 250014, Peoples R China. dzshen@sdnu.edu.cn; lxchen@yic.ac.cn
作者单位	1.Shandong Normal Univ, Coll Chem Chem Engn & Mat Sci, Minist Educ China, Key Lab Mol & Nanomat Probes, Jinan 250014, Peoples R China 2.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China 3.Binzhou Med Univ, Yantai 264003, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Wang, Xiaoyan,Kang, Qi,Shen, Dazhong,et al. Novel monodisperse molecularly imprinted shell for estradiol based on surface imprinted hollow vinyl-SiO2 particles[J]. TALANTA,2014,124:7-13.
APA	Wang, Xiaoyan.,Kang, Qi.,Shen, Dazhong.,Zhang, Zhong.,Li, Jinhua.,...&lxchen@yic.ac.cn.(2014).Novel monodisperse molecularly imprinted shell for estradiol based on surface imprinted hollow vinyl-SiO2 particles.TALANTA,124,7-13.
MLA	Wang, Xiaoyan,et al."Novel monodisperse molecularly imprinted shell for estradiol based on surface imprinted hollow vinyl-SiO2 particles".TALANTA 124(2014):7-13.

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