Molecularly imprinted metal-organic frameworks assisted cloth and paper hybrid microfluidic devices for visual detection of gonyautoxin

doi:10.1016/j.jhazmat.2024.133969

	Molecularly imprinted metal-organic frameworks assisted cloth and paper hybrid microfluidic devices for visual detection of gonyautoxin
	Xiang, Jiawen 1,2; Qi, Ji 1,6; Hu, Die 1,3; Wang, Chao 1,4; Wang, Liyan 1; Wu, Yixuan 1; Chen, Jiadong 6; Zhang, Zhiyang1,2 ; Wang, Xiaoyan 5; Li, Bowei1,2 ; Chen, Lingxin1,2
发表期刊	JOURNAL OF HAZARDOUS MATERIALS
ISSN	0304-3894
	2024-05-05
卷号	469 页码:10
关键词	Gonyautoxin 1/4 Colorimetric sensor Microfluidic device Molecularly imprinted polymer
DOI	10.1016/j.jhazmat.2024.133969
通讯作者	Li, Bowei(bwli@yic.ac.cn) ; Chen, Lingxin(lxchen@yic.ac.cn)
英文摘要	Marine algal toxin contamination is a major threat to human health. Thus, it is crucial to develop rapid and onsite techniques for detecting algal toxins. In this work, we developed colorimetric cloth and paper hybrid microfluidic devices (mu CPADs) for rapid detection of gonyautoxin (GTX1/4) combined with molecularly imprinted polymers. In addition, the metal -organic frameworks (MOFs) composites were applied for this approach by their unique features. Guanosine serves as a dummy template for surface imprinting and has certain structural advantages in recognizing gonyautoxin. MOF@MIPs composites were able to perform a catalytic color reaction using hydrogen peroxide-tetramethylbenzidine for the detection of GTX1/4. The cloth -based sensing substrates were assembled on origami mu PADs to form user-friendly, miniaturized colorimetric mu CPADs. Combined with a smartphone, the proposed colorimetric mu CPADs successfully achieved a low limit of detection of 0.65 mu g/L within the range of 1-200 mu g/L for rapid visual detection of GTX1/4. Moreover, the GTX1/4 of real shellfish and seawater samples were satisfactorily detected to indicate the application prospect of the mu CPADs. The proposed method shows good potential in the low-cost, stable establishment of assays for the rapid detection of environmental biotoxins.
资助机构	National Natural Science Foundation of China Major Scientific Research Instrument Development Project ; National Natural Science Foundation of China ; Shandong Provincial Natural Science Foundation Key Project of China ; Open Fund Project of Key Laboratory of Ocean Observation Technology
收录类别	SCI
语种	英语
关键词[WOS]	PERFORMANCE LIQUID-CHROMATOGRAPHY ; APTAMER ; DESIGN ; TOXINS ; SENSOR
研究领域[WOS]	Engineering ; Environmental Sciences & Ecology
WOS记录号	WOS:001202721600001
引用统计	被引频次：1[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.yic.ac.cn/handle/133337/35311
专题	中国科学院海岸带环境过程与生态修复重点实验室中国科学院海岸带环境过程与生态修复重点实验室_海岸带环境工程技术研究与发展中心
通讯作者	Li, Bowei; Chen, Lingxin
作者单位	1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Yantai Univ, Sch Chem & Chem Engn, Yantai 264005, Peoples R China 4.Harbin Inst Technol Weihai, Dept Appl Chem, Weihai 264209, Peoples R China 5.Binzhou Med Univ, Sch Pharm, Yantai 264003, Peoples R China 6.Chung Ang Univ, Dept Chem, Seoul 06974, South Korea
推荐引用方式 GB/T 7714	Xiang, Jiawen,Qi, Ji,Hu, Die,et al. Molecularly imprinted metal-organic frameworks assisted cloth and paper hybrid microfluidic devices for visual detection of gonyautoxin[J]. JOURNAL OF HAZARDOUS MATERIALS,2024,469:10.
APA	Xiang, Jiawen.,Qi, Ji.,Hu, Die.,Wang, Chao.,Wang, Liyan.,...&Chen, Lingxin.(2024).Molecularly imprinted metal-organic frameworks assisted cloth and paper hybrid microfluidic devices for visual detection of gonyautoxin.JOURNAL OF HAZARDOUS MATERIALS,469,10.
MLA	Xiang, Jiawen,et al."Molecularly imprinted metal-organic frameworks assisted cloth and paper hybrid microfluidic devices for visual detection of gonyautoxin".JOURNAL OF HAZARDOUS MATERIALS 469(2024):10.