The invention relates to heparin detection and especially relates to a method and a device for continuously and rapidly detecting heparin. Protamines are facilitated to diffusing inside a polyion sensitive membrane under the effect of an additional continuous current, so that an electrode is regenerated online to continuously detect the heparin. A polyion sensitive membrane electrode containing the protamines in a film phase is arranged in a film phase analysis system; when a heparin sample flows into a detection basin with a carrier liquid; the electrode is used for generating potential signals under the specificity effect of the protamines and the heparin; and the on-line regeneration of the electrode can be rapidly updated by using the protamines under the effect of the additional continuous current, so as to continuously detect the heparin. According to the method and the device provided by the invention, a flow injection analyzer is adopted for controlling, so that the simplicity and the convenience in operation and the easiness of automation realization can be realized.
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