Dual-Mode Undistorted Visual Fluorescent Sensing Strategy through Manipulating the Coffee-Ring Effect on Microfluidic Paper-Based Chip
Qi, Ji1,2; Li, Bowei1; Lin, Dong1; Du, Zhiqiang1; Fu, Longwen1; Wang, Xiaoyan3; Zhang, Zhiyang1; Luo, Liqiang4; Chen, Lingxin1,3
Source PublicationANALYTICAL CHEMISTRY
ISSN0003-2700
2023-07-07
Volume95Issue:28Pages:10486-10491
DOI10.1021/acs.analchem.3c00947
Corresponding AuthorLi, Bowei(bwli@yic.ac.cn) ; Luo, Liqiang(luck@shu.edu.cn) ; Chen, Lingxin(lxchen@yic.ac.cn)
AbstractTo overcome the insufficient sensitivity due to distortionof thefluorescent images by mobile devices, we first developed a novel dual-modestrategy for undistorted visual fluorescent sensing on & mu;PADby technically manipulating the coffee-ring effect of the fluid sample.Based on the manipulating coffee-ring effect, we divided the horizontaldirection of the resulting fluorescence image into 600 pixels andobtained more accurate quantitative information to avoid image distortion.The bovine serum albumin-stabilized gold nanoclusters-copperion complex was used as the fluorescent probe, combined with a smallimaging box and a smartphone, to achieve a rapid testing of histidinein human urine. The output image was analyzed in dual mode: RGB numericalanalysis in pixel units and the direct measurement of the fluorescentstrips length (limit of detection (LOD) is 0.021 and 0.5 mM, respectively),and improved antidistortion for visual fluorescent sensing. This strategycan overcome the distortion of a smartphone-visualized fluorescentimage and shows great potential for rapid and convenient analysis.
Funding OrganizationNational Natural Science Foundation of China ; Shandong Provincial Natural Science Foundation Key Project ; Open Fund Project of Key Laboratory of Ocean Observation Technology
Indexed BySCI
Language英语
WOS KeywordASSAY
WOS Research AreaChemistry
WOS IDWOS:001024816600001
Citation statistics
Cited Times:2[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.yic.ac.cn/handle/133337/33364
Collection中国科学院海岸带环境过程与生态修复重点实验室
中国科学院海岸带环境过程与生态修复重点实验室_海岸带环境工程技术研究与发展中心
Corresponding AuthorLi, Bowei; Luo, Liqiang; Chen, Lingxin
Affiliation1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China
2.MNR, Key Lab Ocean Observat Technol, Tianjin 300110, Peoples R China
3.Binzhou Med Univ, Sch Pharm, Yantai 264003, Peoples R China
4.Shanghai Univ, Coll Sci, Shanghai 200444, Peoples R China
Recommended Citation
GB/T 7714
Qi, Ji,Li, Bowei,Lin, Dong,et al. Dual-Mode Undistorted Visual Fluorescent Sensing Strategy through Manipulating the Coffee-Ring Effect on Microfluidic Paper-Based Chip[J]. ANALYTICAL CHEMISTRY,2023,95(28):10486-10491.
APA Qi, Ji.,Li, Bowei.,Lin, Dong.,Du, Zhiqiang.,Fu, Longwen.,...&Chen, Lingxin.(2023).Dual-Mode Undistorted Visual Fluorescent Sensing Strategy through Manipulating the Coffee-Ring Effect on Microfluidic Paper-Based Chip.ANALYTICAL CHEMISTRY,95(28),10486-10491.
MLA Qi, Ji,et al."Dual-Mode Undistorted Visual Fluorescent Sensing Strategy through Manipulating the Coffee-Ring Effect on Microfluidic Paper-Based Chip".ANALYTICAL CHEMISTRY 95.28(2023):10486-10491.
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