Effects and mechanisms of decabromodiphenyl ethane on Chlorella sorokiniana: Transcriptomics, proteins and fatty acid production br

doi:10.1016/j.marenvres.2022.105764

	Effects and mechanisms of decabromodiphenyl ethane on Chlorella sorokiniana: Transcriptomics, proteins and fatty acid production br
	Wang, Wenjing; Sheng, Yanqing
发表期刊	MARINE ENVIRONMENTAL RESEARCH
ISSN	0141-1136
	2022-11-01
卷号	181 页码:10
关键词	Chlorella sorokiniana Decabromodiphenyl ethane Dimethyl sulfoxide Transcriptome Quantitative proteomics
DOI	10.1016/j.marenvres.2022.105764
通讯作者	Sheng, Yanqing(yqsheng@yic.ac.cn)
英文摘要	Decabromodiphenyl ethane is a novel brominated flame retardant, that has always been dissolved in organic solvents to explore its activities on aquatic organisms. In this study, the influences of decabromodiphenyl ethane on the microalga Chlorella sorokiniana (C. sorokiniana) were studied, and three microalgae treatments, including decabromodiphenyl ethane dissolved in dimethyl sulfoxide solvent (DBDPE treatment), dimethyl sulfoxide alone (control II) or untreated (control I) were used in the experiment, respectively. The results showed that the growth of C. sorokiniana was remarkably enhanced in the DBDPE treatment compared with the control I and II groups. Conjoint analysis of transcriptomics and quantitative proteome displayed that the upregulated differentially expressed genes and proteins of DBDPE:control I were enriched in 6 pathways, and downregulated genes/proteins of DBDPE:control I were enriched in 3 pathways. The upregulated differentially expressed genes and proteins of DBDPE:control II were enriched in 4 pathways, and downregulated genes/proteins of DBDPE:control II were enriched in 6 pathways. In addition, decabromodiphenyl ethane changed the fatty acid concentration in C. sorokiniana cells. The activities of superoxide dismutase were enhanced when C. sorokiniana were treated by decabromodiphenyl ethane. The data highlighted that the mRNA and protein expression relating to the fatty acid production, of C. sorokiniana were significantly affected by decabromodiphenyl ethane, and decabromodiphenyl ethane pollution changed the physiological metabolism of microalgae and had harmful effects on natural environments.
收录类别	SCI
语种	英语
关键词[WOS]	TOXICITY ; ETHER ; IDENTIFICATION ; ENRICHMENT ; ALGAE ; KEGG
研究领域[WOS]	Environmental Sciences & Ecology ; Marine & Freshwater Biology ; Toxicology
WOS记录号	WOS:000868836900001
引用统计	被引频次：2[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.yic.ac.cn/handle/133337/31943
专题	中国科学院海岸带环境过程与生态修复重点实验室中国科学院海岸带环境过程与生态修复重点实验室_海岸带环境工程技术研究与发展中心
通讯作者	Sheng, Yanqing
作者单位	Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn Technol Shandong Pro, Yantai, Shandong, Peoples R China
推荐引用方式 GB/T 7714	Wang, Wenjing,Sheng, Yanqing. Effects and mechanisms of decabromodiphenyl ethane on Chlorella sorokiniana: Transcriptomics, proteins and fatty acid production br[J]. MARINE ENVIRONMENTAL RESEARCH,2022,181:10.
APA	Wang, Wenjing,&Sheng, Yanqing.(2022).Effects and mechanisms of decabromodiphenyl ethane on Chlorella sorokiniana: Transcriptomics, proteins and fatty acid production br.MARINE ENVIRONMENTAL RESEARCH,181,10.
MLA	Wang, Wenjing,et al."Effects and mechanisms of decabromodiphenyl ethane on Chlorella sorokiniana: Transcriptomics, proteins and fatty acid production br".MARINE ENVIRONMENTAL RESEARCH 181(2022):10.