Thin membrane-based potentiometric sensors for sensitive detection of polyions

doi:10.1039/d2ay01223e

	Thin membrane-based potentiometric sensors for sensitive detection of polyions
	Wang, Kaikai 1,2; Liang, Rongning1 ; Qin, Wei1
发表期刊	ANALYTICAL METHODS
ISSN	1759-9660
	2022-10-20
卷号	14 期号:40 页码:4008-4013
DOI	10.1039/d2ay01223e
通讯作者	Liang, Rongning(rnliang@yic.ac.cn)
英文摘要	A novel protocol for development of sensitive and rapid polymeric membrane polyion sensitive electrodes has been explored in this work. In contrast to the traditional polyion electrodes which usually have a sensing membrane thickness of 100 similar to 200 mu m, a thin membrane electrode with a membrane thickness of 5 mu m is proposed to detect polyions. By using such thin membrane configuration, the diffusion of polyions from the organic boundary layer into the bulk of the membrane can be effectively blocked. The induced accumulation of polyions in the membrane boundary layer largely enhances the obtained potential response. It has been found that the proposed electrode shows a remarkably improved sensitivity and measurement time over conventional potentiometric polyion sensors based on the thick membranes. By using protamine as a model of polyions, the new concept offers a detection limit nearly two orders of magnitude lower than those obtained by the traditional thick-membrane polyion electrodes for potentiometric measurements of polyions. The proposed polyion sensing platform offers great promise in the sensitive and rapid detection of polyions as well as other polyion-involved bioanalyses.
资助机构	National Natural Science Foundation of China ; Key Deployment Project of Centre for Ocean Mega-Research of Science, Chinese Academy of Sciences ; Youth Innovation Promotion Association of the Chinese Academy of Sciences ; Taishan Scholar Program of Shandong Province
收录类别	SCI
语种	英语
关键词[WOS]	ION-SELECTIVE ELECTRODES ; ELECTROCHEMICAL ASSAY ; REVERSIBLE DETECTION ; SOLID-CONTACT ; HEPARIN ; INHIBITORS ; BLOOD
研究领域[WOS]	Chemistry ; Food Science & Technology ; Spectroscopy
WOS记录号	WOS:000865259500001
引用统计	被引频次：1[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.yic.ac.cn/handle/133337/31761
专题	中国科学院海岸带环境过程与生态修复重点实验室中国科学院海岸带环境过程与生态修复重点实验室_海岸带环境过程实验室
通讯作者	Liang, Rongning
作者单位	1.Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, CAS Key Lab Coastal Environm Proc & Ecol Remediat, YICCAS,Shandong Key Lab Coastal Environm Proc, Yantai 264003, Shandong, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Wang, Kaikai,Liang, Rongning,Qin, Wei. Thin membrane-based potentiometric sensors for sensitive detection of polyions[J]. ANALYTICAL METHODS,2022,14(40):4008-4013.
APA	Wang, Kaikai,Liang, Rongning,&Qin, Wei.(2022).Thin membrane-based potentiometric sensors for sensitive detection of polyions.ANALYTICAL METHODS,14(40),4008-4013.
MLA	Wang, Kaikai,et al."Thin membrane-based potentiometric sensors for sensitive detection of polyions".ANALYTICAL METHODS 14.40(2022):4008-4013.