Institutional Repository of Key Laboratory of Coastal Zone Environmental Processes, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences (KLCEP)
| The distinct toxicity effects between commercial and realistic polystyrene microplastics on microbiome and histopathology of gut in zebrafish | |
Guo, Xiaotong1,4; Lv, Min1,5 ; Li, Jinhua1,5; Ding, Jing2; Wang, Yunqing1,5; Fu, Longwen1,5; Sun, Xiyan1,5; Han, Xiaoyue1,4; Chen, Lingxin1,3,5
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| Source Publication | JOURNAL OF HAZARDOUS MATERIALS
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| ISSN | 0304-3894 |
| 2022-07-15 | |
| Volume | 434Pages:11 |
| Keyword | Realistic microplastics Enrofloxacin Combined exposure Gut microbiome Histological analysis |
| DOI | 10.1016/j.jhazmat.2022.128874 |
| Abstract | As a ubiquitous emerging pollutant, microplastics (MPs) have attracted widespread attention. At this stage, researchers mainly employed commercial MPs (CMPs) as the model particles to explore the toxic effects of MPs. But whether CMPs can reflect the effects of realistic MPs (RMPs) still remains unknown. Herein, the effects of commercial and realistic polystyrene MPs on gut microbiota of zebrafish were compared. Considering MPs co-exist with antibiotics in real environment, we further distinguished the effects of CMPs and RMPs when they co-existed with enrofloxacin (ENR). The results revealed that while both CMPs and RMPs significantly shifted the gut microbiota, CMPs exhibited stronger toxic effects and more severe damage to gut. Furthermore, ENR exhibited a distinct effect with both CMPs and RMPs on gut microbiota, while the addition of CMPs and RMPs significantly alleviated the toxicity of ENR. In addition, analysis via Kyoto Encyclopedia of Genes and Genomes pathway database revealed that seven major level 1 pathways associated with metabolism, information processing and diseases in the microbial community were affected. Taken together, this work is the first to report that CMPs could not represent RMPs in terms of toxicity and other behaviors, reminding people the limits of using CMPs in ecotoxicology studies. |
| Indexed By | SCI |
| Language | 英语 |
| WOS Keyword | AQUATIC ORGANISMS ; EXPOSURE ; POLYETHYLENE ; MUSSELS |
| WOS Research Area | Engineering ; Environmental Sciences & Ecology |
| WOS ID | WOS:000793548200004 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.yic.ac.cn/handle/133337/31033 |
| Collection | 中科院海岸带环境过程与生态修复重点实验室 中科院海岸带环境过程与生态修复重点实验室_海岸带环境工程技术研究与发展中心 |
| Corresponding Author | Lv, Min; Chen, Lingxin |
| Affiliation | 1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China 2.Yantai Univ, Sch Environm & Mat Engn, Yantai 264005, Peoples R China 3.Pilot Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266237, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 5.Chinese Acad Sci, Ctr Ocean Megasci, Qingdao 266071, Peoples R China |
| Recommended Citation GB/T 7714 | Guo, Xiaotong,Lv, Min,Li, Jinhua,et al. The distinct toxicity effects between commercial and realistic polystyrene microplastics on microbiome and histopathology of gut in zebrafish[J]. JOURNAL OF HAZARDOUS MATERIALS,2022,434:11. |
| APA | Guo, Xiaotong.,Lv, Min.,Li, Jinhua.,Ding, Jing.,Wang, Yunqing.,...&Chen, Lingxin.(2022).The distinct toxicity effects between commercial and realistic polystyrene microplastics on microbiome and histopathology of gut in zebrafish.JOURNAL OF HAZARDOUS MATERIALS,434,11. |
| MLA | Guo, Xiaotong,et al."The distinct toxicity effects between commercial and realistic polystyrene microplastics on microbiome and histopathology of gut in zebrafish".JOURNAL OF HAZARDOUS MATERIALS 434(2022):11. |
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