Novel Inulin Derivatives Modified with Schiff Bases: Synthesis, Characterization, and Antifungal Activity

doi:10.3390/polym11060998

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	Novel Inulin Derivatives Modified with Schiff Bases: Synthesis, Characterization, and Antifungal Activity
	Chen, Y ; Mi, YQ ; Sun, XQ ; Zhang, JJ ; Li, Q; Ji, NY; Guo, ZY
发表期刊	POLYMERS
	2019-06
卷号	11 期号:6 页码:998
关键词	inulin Schiff base antifungal activity
研究领域	Polymer Science
DOI	10.3390/polym11060998
产权排序	[Chen, Yuan; Mi, Yingqi; Sun, Xueqi; Zhang, Jingjing; Li, Qing; Ji, Naiyun; Guo, Zhanyong] Chinese Acad Sci, Key Lab Coastal Biol & Bioresource Utilizat, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China; [Chen, Yuan; Mi, Yingqi; Sun, Xueqi; Zhang, Jingjing; Ji, Naiyun; Guo, Zhanyong] Chinese Acad Sci, Ctr Ocean Mega Sci, 7 Nanhai Rd, Qingdao 266071, Peoples R China; [Chen, Yuan; Mi, Yingqi; Sun, Xueqi; Zhang, Jingjing; Ji, Naiyun; Guo, Zhanyong] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
通讯作者	Ji, Naiyun(nyji@yic.ac.cn) ; Guo, Zhanyong(zhanyongguo@hotmail.com)
作者部门	海岸带生物资源高效利用研究与发展中心
英文摘要	In this paper, we report chemical modifications of inulin by seven kinds of aromatic Schiff bases, which are different from their substituent groups. The obtained inulin derivatives were confirmed by FTIR, H-1 NMR, and C-13 NMR. Then, we studied their antifungal activity against four kinds of plant pathogens involving Botrytis cinerea, Fusarium oxysporum f. sp. cucumerium Owen, Fusarium oxysporum f. sp. niveum, and Phomopsis asparagi by the mycelium growth rate method. The results revealed that all inulin derivatives were endowed with significant antifungal activity compared to inulin. Among them, 6-amino-(N-4-chlorobenzylidene)-6-deoxy-3,4-di-O-acetyl inulin (4CBSAIL) and 6-amino-(N-3,4-dichlorobenzylidene)-6-deoxy-3,4-di-O-acetyl inulin (3,4DCBSAIL), which were synthesized from p-chlorobenzaldehyde and 3,4-dichlorobenzaldehyde, could completely inhibit the growth of the test fungi at 1.0 mg/mL. The inhibitory indices of the inulin derivatives were related to the type, position, and number of substituent groups (halogens) on the Schiff bases. The results confirmed that it was feasible to chemically modify inulin with Schiff bases to confer high antifungal activity to inulin. The products described in this paper have great potential as alternatives to some harmful pesticides used for plant disease control.
文章类型	Article
资助机构	Seed Project of the Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences [YIC Y755031011] ; National Natural Science Foundation of ChinaNational Natural Science Foundation of China [41576156] ; Shandong Province Science and Technology Development Plan [2015GSF121045] ; Yantai Science and Technology Development Plan [2015ZH078] ; Public Science and Technology Research Funds Projects of Ocean [201505022-3]
收录类别	SCI
语种	英语
关键词[WOS]	CHEMICAL-MODIFICATIONS ; BIOLOGICAL-ACTIVITY ; DELIVERY ; EXTRACTION
研究领域[WOS]	Polymer Science
WOS记录号	WOS:000473819100070
引用统计	被引频次：10[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.yic.ac.cn/handle/133337/24927
专题	海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室
作者单位	1.Chinese Acad Sci, Key Lab Coastal Biol & Bioresource Utilizat, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China; 2.Chinese Acad Sci, Ctr Ocean Mega Sci, 7 Nanhai Rd, Qingdao 266071, Peoples R China; 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Chen, Y,Mi, YQ,Sun, XQ,et al. Novel Inulin Derivatives Modified with Schiff Bases: Synthesis, Characterization, and Antifungal Activity[J]. POLYMERS,2019,11(6):998.
APA	Chen, Y.,Mi, YQ.,Sun, XQ.,Zhang, JJ.,Li, Q.,...&Guo, ZY.(2019).Novel Inulin Derivatives Modified with Schiff Bases: Synthesis, Characterization, and Antifungal Activity.POLYMERS,11(6),998.
MLA	Chen, Y,et al."Novel Inulin Derivatives Modified with Schiff Bases: Synthesis, Characterization, and Antifungal Activity".POLYMERS 11.6(2019):998.

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