| Preparation of starch derivatives bearing urea groups and the evaluation of antioxidant, antifungal, and antibacterial activities | |
Zhang, JJ; Mi, YQ; Sun, XQ; Chen, Y; Gu, GD; Tan, WQ ; Li, Q; Dong, F; Guo, ZY
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| 发表期刊 | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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| ISSN | 0141-8130 |
| 2019-12-01 | |
| 卷号 | 141页码:1271-1279 |
| 关键词 | Bioactivities Starch derivatives Urea groups |
| 研究领域 | Biochemistry & Molecular Biology ; Chemistry, Applied ; Polymer Science |
| DOI | 10.1016/j.ijbiomac.2019.09.014 |
| 产权排序 | [Zhang, Jingjing; Mi, Yingqi; Sun, Xueqi; Chen, Yuan; Tan, Wenqiang; Li, Qing; Dong, Fang; Guo, Zhanyong] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China; [Zhang, Jingjing; Mi, Yingqi; Sun, Xueqi; Chen, Yuan; Tan, Wenqiang; Li, Qing; Dong, Fang; Guo, Zhanyong] Chinese Acad Sci, Ctr Ocean Mega Sci, 7 Nanhai Rd, Qingdao 266071, Peoples R China; [Zhang, Jingjing; Mi, Yingqi; Sun, Xueqi; Chen, Yuan; Guo, Zhanyong] Univ Chinese Acad Sci, Beijing 100049, Peoples R China; [Gu, Guodong] Alliance Pharma Inc, 17 Lee Blvd, Malvern, PA 19355 USA |
| 通讯作者 | Dong, Fang(fdong@yic.ac.cn) ; Guo, Zhanyong(zhanyongguo@hotmail.com) |
| 作者部门 | 海岸带生物资源高效利用研究与发展中心 |
| 英文摘要 | Several starch derivatives bearing urea groups (TUCAST, MTUCAST, and PTUCAST) based on 6-O-chloroacetylated starch (CAST) were successfully designed and synthesized. FT-IR, H-1 NMR spectroscopy, and elemental analysis were carried out to identify the structural characteristics of starch derivatives. The antioxidant activity of starch derivatives was tested by superoxide-radical scavenging and hydroxyl radical scavenging assays. Their antifungal activity against Fusarium oxysporum f. sp. cucumebrium Owen, Phomopsis asparagus, and Fusarium oxysporum f. sp. niveum was estimated by hyphal measurement. Furthermore, the antibacterial activity against Escherichia coli and Staphylococcus aureus was evaluated by optical density method. Compared to starch, the products bearing urea groups showed enhanced antifungal action as well as an excellent antioxidant and antibacterial activities. Their bioactivities decreased roughly in the order of PTUCAST > MTUCAST > TUCAST > CAST > starch, which matched with the electron -withdrawing property of the different substituted groups of urea. Besides, the cytotoxic activity of starch and synthesized derivatives against L929 cells was evaluated using CCK-8 assay in vitro and all samples showed weak cytotoxicity. The results suggested that these novel starch derivatives possessing satisfactory bioactivities could be widely used in the food industry. (C) 2019 Elsevier B.V. All rights reserved. |
| 文章类型 | Article |
| 资助机构 | National Natural Science Foundation of ChinaNational Natural Science Foundation of China [41576156] ; Natural Science Foundation of Shandong Province of ChinaNatural Science Foundation of Shandong Province [ZR2017BD015] ; Science and Technology Service Network Initiative of Chinese academy of sciences [KFJ-STS-ZDTP-023] ; seed project of Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences [YIC Y755031011] |
| 收录类别 | SCI |
| 语种 | 英语 |
| 关键词[WOS] | 1,3,4-THIADIAZOLE |
| 研究领域[WOS] | Biochemistry & Molecular Biology ; Chemistry, Applied ; Polymer Science |
| WOS记录号 | WOS:000506713000128 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.yic.ac.cn/handle/133337/24799 |
| 专题 | 海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心 海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室 |
| 作者单位 | 1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China; 2.Chinese Acad Sci, Ctr Ocean Mega Sci, 7 Nanhai Rd, Qingdao 266071, Peoples R China; 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China; 4.Alliance Pharma Inc, 17 Lee Blvd, Malvern, PA 19355 USA |
| 推荐引用方式 GB/T 7714 | Zhang, JJ,Mi, YQ,Sun, XQ,et al. Preparation of starch derivatives bearing urea groups and the evaluation of antioxidant, antifungal, and antibacterial activities[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2019,141:1271-1279. |
| APA | Zhang, JJ.,Mi, YQ.,Sun, XQ.,Chen, Y.,Gu, GD.,...&Guo, ZY.(2019).Preparation of starch derivatives bearing urea groups and the evaluation of antioxidant, antifungal, and antibacterial activities.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,141,1271-1279. |
| MLA | Zhang, JJ,et al."Preparation of starch derivatives bearing urea groups and the evaluation of antioxidant, antifungal, and antibacterial activities".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 141(2019):1271-1279. |
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| Preparation of starc（1747KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | 浏览 请求全文 | |
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