| Improved Antioxidant and Antifungal Activity of Chitosan Derivatives Bearing Urea Groups | |
Zhang, JJ; Mi, YQ; Sun, XQ; Chen, Y; Miao, Q; Tan, WQ ; Li, Q; Dong, F; Guo, ZY
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| 发表期刊 | STARCH-STARKE
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| ISSN | 0038-9056 |
| 2020 | |
| 卷号 | 72期号:5-6页码:1900205 |
| 关键词 | antifungal activity antioxidant activity chitosan derivatives urea groups |
| 研究领域 | Food Science & Technology |
| DOI | 10.1002/star.201900205 |
| 产权排序 | [Zhang, Jingjing; Mi, Yingqi; Sun, Xueqi; Chen, Yuan; Miao, Qin; Tan, Wenqiang; Li, Qing; Dong, Fang; Guo, Zhanyong] Chinese Acad Sci, Key Lab Coastal Biol & Bioresource Utilizat, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China; [Zhang, Jingjing; Mi, Yingqi; Sun, Xueqi; Chen, Yuan; Miao, Qin; Tan, Wenqiang; Li, Qing; Dong, Fang; Guo, Zhanyong] Chinese Acad Sci, Ctr Ocean Mega Sci, 7 Nanhai Rd, Qingdao 266071, Peoples R China; [Zhang, Jingjing; Mi, Yingqi; Sun, Xueqi; Chen, Yuan; Guo, Zhanyong] Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 通讯作者 | Guo, Zhanyong(zhanyongguo@hotmail.com) |
| 作者部门 | 海岸带生物学与生物资源保护实验室 |
| 英文摘要 | Eight novel chitosan derivatives bearing urea groups are designed and synthesized. Fourier transform infrared spectroscopy, H-1 nuclear magnetic resonance spectrometer, and elemental analysis are performed to confirm the structural characteristics of chitosan derivatives. The antioxidant activities, including superoxide radicals' scavenging activity, 1,1-diphenyl-2-picrylhydrazyl radicals' scavenging activity, and hydroxyl radical' scavenging activity, of the derivatives are explored within different concentrations in the reaction system. In vitro fungicidal activity of these compounds is further tested against Fusarium oxysporum f. sp. niveum, Phomopsis asparagus, F. oxysporum f. sp. cucumebrium Owen, and Botrytis cinerea, respectively, particularly compounds exhibit significant control effect at 1.0 mg mL(-1). The experimental results indicate that the products bearing urea groups show enhanced antifungal property and antioxidant activity compared with pristine chitosan. Meanwhile, their bioactivities follow some regularity on the whole, that is, they are related to the electron-withdrawing property of the different substituted groups of urea. Derivatives with stronger electron-withdrawing property will have higher biological activities. L929 cells are used to carry out cytotoxicity test of chitosan and chitosan derivatives by Cell Counting Kit-8 assay. The results indicate that some of the samples show low cytotoxicity. This research will be helpful to broaden the application of chitosan in materials. |
| 文章类型 | Article |
| 资助机构 | Natural Science Foundation of Shandong Province Science and Technology Development Plan [2019GHY112010] ; National Natural Science Foundation of ChinaNational Natural Science Foundation of China [41576156] ; Natural Science Foundation of Shandong Province of ChinaNatural Science Foundation of Shandong Province [ZR2017BD015, ZR2019BD064] |
| 收录类别 | SCI |
| 语种 | 英语 |
| 关键词[WOS] | IN-VITRO ; ENHANCED ANTIOXIDANT ; ANTIBACTERIAL ; COMPLEXES |
| 研究领域[WOS] | Food Science & Technology |
| WOS记录号 | WOS:000505836700001 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.yic.ac.cn/handle/133337/24770 |
| 专题 | 海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心 海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室 |
| 作者单位 | 1.Chinese Acad Sci, Key Lab Coastal Biol & Bioresource Utilizat, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China; 2.Chinese Acad Sci, Ctr Ocean Mega Sci, 7 Nanhai Rd, Qingdao 266071, Peoples R China; 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, JJ,Mi, YQ,Sun, XQ,et al. Improved Antioxidant and Antifungal Activity of Chitosan Derivatives Bearing Urea Groups[J]. STARCH-STARKE,2020,72(5-6):1900205. |
| APA | Zhang, JJ.,Mi, YQ.,Sun, XQ.,Chen, Y.,Miao, Q.,...&Guo, ZY.(2020).Improved Antioxidant and Antifungal Activity of Chitosan Derivatives Bearing Urea Groups.STARCH-STARKE,72(5-6),1900205. |
| MLA | Zhang, JJ,et al."Improved Antioxidant and Antifungal Activity of Chitosan Derivatives Bearing Urea Groups".STARCH-STARKE 72.5-6(2020):1900205. |
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| Improved Antioxidant（2399KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | 浏览 请求全文 | |
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