| Highly Sensitive and Reproducible SERS Sensor for Biological pH Detection Based on a Uniform Gold Nanorod Array Platform | |
Bi, Liyan; Wang, Yunqing ; Yang, Ying; Li, Yuling; Mo, Shanshan; Zheng, Qingyin; Chen, Lingxin
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| 发表期刊 | ACS APPLIED MATERIALS & INTERFACES
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| ISSN | 1944-8244 |
| 2018-05-09 | |
| 卷号 | 10期号:18页码:15381-15387 |
| 关键词 | gold nanorod array 4-MPy SERS RSD pH sensor CS7BL/6 mouse blood |
| 研究领域 | Science & Technology - Other Topics ; Materials Science |
| DOI | 10.1021/acsami.7b19347 |
| 产权排序 | [Bi, Liyan; Yang, Ying; Zheng, Qingyin] Binzhou Med Univ, Transformat Otol & Neurosci Ctr, Coll Special Educ, Yantai 264003, Peoples R China; [Li, Yuling] Binzhou Med Univ, Dept Pathophysiol, Yantai 264003, Peoples R China; [Mo, Shanshan] Binzhou Med Univ, Dept Pharm, Yantai 264003, Peoples R China; [Wang, Yunqing; Chen, Lingxin] Yantai Inst Coastal Zone Res, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China |
| 作者部门 | 海岸带环境过程实验室 |
| 英文摘要 | Conventional research on surface-enhanced Raman scattering (SERS)-based pH sensors often depends on nanoparticle aggregation, whereas the variability in nanoparticle aggregation gives rise to poor repeatability in the SERS signal. Herein, we fabricated a gold nanorod array platform via an efficient evaporative self-assembly method. The platform exhibits great SERS sensitivity with an enhancement factor of 5.6 X 10(7) and maintains excellent recyclability and reproducibility with relative standard deviation (RSD) values of less than 8%. On the basis of the platform, we developed a highly sensitive bovine serum albumin (BSA)-coated 4-mercaptopyridine (4-MPy)-linked (BMP) SERS-based pH sensor to report pH ranging from pH 3.0 to pH 8.0. The intensity ratio variation of 1004 and 1096 cm(-1) in 4-MPy showed excellent pH sensitivity, which decreased as the surrounding pH increased. Furthermore, this BMP SERS-based pH sensor was employed to measure the pH value in C57BL/6 mouse blood. We have demonstrated that the pH sensor has great advantages such as good stability, reliability, and accuracy, which could be extended for the design of point-of-care devices. |
| 文章类型 | Article |
| 资助机构 | National Natural Science Foundation of China [21605005, 81530030, 81573393, 21575159, 51401031 |
| 收录类别 | SCI |
| 语种 | 英语 |
| 关键词[WOS] | ENHANCED RAMAN-SCATTERING ; FEMTOMOLAR DETECTION ; NANOPARTICLES ; SPECTROSCOPY ; FLUORESCENCE ; DECORATION ; MONOLAYER ; SUBSTRATE ; FILMS ; SHAPE |
| 研究领域[WOS] | Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary |
| WOS记录号 | WOS:000432205800007 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.yic.ac.cn/handle/133337/24463 |
| 专题 | 中国科学院海岸带环境过程与生态修复重点实验室_海岸带环境过程实验室 中国科学院海岸带环境过程与生态修复重点实验室 |
| 作者单位 | 1.Binzhou Med Univ, Transformat Otol & Neurosci Ctr, Coll Special Educ, Yantai 264003, Peoples R China; 2.Binzhou Med Univ, Dept Pathophysiol, Yantai 264003, Peoples R China; 3.Binzhou Med Univ, Dept Pharm, Yantai 264003, Peoples R China; 4.Yantai Inst Coastal Zone Res, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China |
| 推荐引用方式 GB/T 7714 | Bi, Liyan,Wang, Yunqing,Yang, Ying,et al. Highly Sensitive and Reproducible SERS Sensor for Biological pH Detection Based on a Uniform Gold Nanorod Array Platform[J]. ACS APPLIED MATERIALS & INTERFACES,2018,10(18):15381-15387. |
| APA | Bi, Liyan.,Wang, Yunqing.,Yang, Ying.,Li, Yuling.,Mo, Shanshan.,...&Chen, Lingxin.(2018).Highly Sensitive and Reproducible SERS Sensor for Biological pH Detection Based on a Uniform Gold Nanorod Array Platform.ACS APPLIED MATERIALS & INTERFACES,10(18),15381-15387. |
| MLA | Bi, Liyan,et al."Highly Sensitive and Reproducible SERS Sensor for Biological pH Detection Based on a Uniform Gold Nanorod Array Platform".ACS APPLIED MATERIALS & INTERFACES 10.18(2018):15381-15387. |
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