| Lipid Bilayer-Enabled Synthesis of Waxberry-like Core-Fluidic Satellite Nanoparticles: Toward Ultrasensitive Surface-Enhanced Raman Scattering Tags for Bioimaging | |
Mei, Rongchao1,2; Wang, Yunqing1,2 ; Liu, Wanhui2; Chen, Lingxin1,3
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| 发表期刊 | ACS APPLIED MATERIALS & INTERFACES
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| ISSN | 1944-8244 |
| 2018-07-18 | |
| 卷号 | 10期号:28页码:23605-23616 |
| 关键词 | gold nanoparticle core-satellite nanoparticle in situ growth lipid bilayer surface-enhanced Raman scattering tags bioimaging |
| 研究领域 | Science & Technology - Other Topics ; Materials Science |
| DOI | 10.1021/acsami.8b06253 |
| 产权排序 | [Mei, Rongchao; Wang, Yunqing; Chen, Lingxin] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn Technol Shandong Pr, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China; [Mei, Rongchao; Wang, Yunqing; Liu, Wanhui] Yantai Univ, Collaborat Innovat Ctr Adv Drug Delivery Syst & B, Key Lab Mol Pharmacol & Drug Evaluat, Sch Pharm,Minist Educ, Yantai 264005, Peoples R China; [Chen, Lingxin] Yantai Univ, Coll Chem & Chem Engn, Yantai 264005, Peoples R China |
| 通讯作者 | Wang, Yunqing(yqwang@yic.ac.cn) ; Chen, Lingxin(lxchen@yic.ac.cn) |
| 作者部门 | 海岸带环境过程实验室 |
| 英文摘要 | Herein, we presented waxberry-like core satellite (C-S) nanoparticles (NPs) prepared by an in situ growth of satellite gold NPs on spherical phospholipid bilayer-coated gold cores. The fluidic lipid bilayer cross-linker was reported for the first time, which imparted several novel morphological and optical properties to the C-S NPs. First, it regulated the anisotropic growth of the satellite NPs into vertically oriented nanorods on the core NP surface. Thus, an interesting waxberry-like nanostructure could be obtained, which was different from the conventional raspberry-like C-S structures decorated with spherical satellite NPs. Second, the satellite NPs were "soft-landed" on the lipid bilayer and could move on the core NP surface under certain conditions. The movement induced tunable plasmonic features in the C-S NPs. Furthermore, the fluidic lipid bilayer was capable of not only holding an abundance of reporter molecules but also delivering them to the hotspots at the junctions between the core and satellite NPs, which made the C-S NPs an excellent candidate for preparing ultrasensitive surface-enhanced Raman scattering (SERS) tags. The bioimaging capabilities of the C-S NP-based SERS tags were successfully demonstrated in living cells and mice. The developed SERS tags hold great potential for bioanalysis and medical diagnostics. |
| 文章类型 | Article |
| 资助机构 | National Natural Science Foundation of China ; Science and Technology Development Plan of Shandong Province of China ; Youth Innovation Promotion Association CAS ; Defense Science and Technology Innovation Fund of the Chinese Academy of Sciences ; Instrument Developing Project of the Chinese Academy of Sciences |
| 收录类别 | SCI |
| 语种 | 英语 |
| 关键词[WOS] | GOLD NANOPARTICLES ; SERS TAGS ; PLASMONIC SUPERSTRUCTURES ; PHOSPHOLIPID-BILAYERS ; PHOTOTHERMAL THERAPY ; OPTICAL-PROPERTIES ; SPECTROSCOPY ; ASSEMBLIES ; LIPOSOMES ; CANCER |
| 研究领域[WOS] | Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary |
| WOS记录号 | WOS:000439528400021 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.yic.ac.cn/handle/133337/24435 |
| 专题 | 中国科学院海岸带环境过程与生态修复重点实验室_海岸带环境过程实验室 中国科学院海岸带环境过程与生态修复重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn Technol Shandong Pr, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China; 2.Yantai Univ, Collaborat Innovat Ctr Adv Drug Delivery Syst & B, Key Lab Mol Pharmacol & Drug Evaluat, Sch Pharm,Minist Educ, Yantai 264005, Peoples R China; 3.Yantai Univ, Coll Chem & Chem Engn, Yantai 264005, Peoples R China |
| 推荐引用方式 GB/T 7714 | Mei, Rongchao,Wang, Yunqing,Liu, Wanhui,et al. Lipid Bilayer-Enabled Synthesis of Waxberry-like Core-Fluidic Satellite Nanoparticles: Toward Ultrasensitive Surface-Enhanced Raman Scattering Tags for Bioimaging[J]. ACS APPLIED MATERIALS & INTERFACES,2018,10(28):23605-23616. |
| APA | Mei, Rongchao,Wang, Yunqing,Liu, Wanhui,&Chen, Lingxin.(2018).Lipid Bilayer-Enabled Synthesis of Waxberry-like Core-Fluidic Satellite Nanoparticles: Toward Ultrasensitive Surface-Enhanced Raman Scattering Tags for Bioimaging.ACS APPLIED MATERIALS & INTERFACES,10(28),23605-23616. |
| MLA | Mei, Rongchao,et al."Lipid Bilayer-Enabled Synthesis of Waxberry-like Core-Fluidic Satellite Nanoparticles: Toward Ultrasensitive Surface-Enhanced Raman Scattering Tags for Bioimaging".ACS APPLIED MATERIALS & INTERFACES 10.28(2018):23605-23616. |
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