Switchable zipper-like thermoresponsive molecularly imprinted polymers for selective recognition and extraction of estradiol

doi:10.1016/j.talanta.2017.08.019

	Switchable zipper-like thermoresponsive molecularly imprinted polymers for selective recognition and extraction of estradiol
	Xiong, Huihuang 1,2; Wu, Xiaqing 1,2; Lu, Wenhui 2; Fu, Junqing 2; Peng, Hailong 1,3; Li, Jinhua2 ; Wang, Xiaoyan 2,4; Xiong, Hua 1; Chen, Lingxin2 ; Xiong, Hua(Nanchang Univ, State Key Lab Food Sci & Technol, Nanchang 330047, Jiangxi, Peoples R China); Chen, Lingxin(Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China)
发表期刊	TALANTA
ISSN	0039-9140
	2018
卷号	176 页码:187-194
关键词	Molecularly Imprinted Polymers Thermoresponsive Zipper-like Estradiol Dispersive Solid-phase Extraction
研究领域	Chemistry, Analytical
DOI	10.1016/j.talanta.2017.08.019
产权排序	第2完成单位
作者部门	海岸带环境工程技术研究与发展中心
英文摘要	Zipper-like thermoresponsive molecularly imprinted polymers (MIPs) were prepared based on interpolymer complexation via the synergy of dual functional monomers of acrylamide (AAm) and 2-acrylamide-2-methyl propanesulfonic acid (AMPS) for selective recognition and extraction of estradiol (E2) by temperature regulation. The resulting E2-MIPs attained controlled adsorption and release of E2 in response to temperature change, with higher adsorption capacity (8.78 mg/g) and stronger selectivity (imprinting factor was 3.18) at 30 degrees C compared with that at 20 and 40 degrees C; the zipper-like interpolymer interaction between poly(AAm) and poly(AMPS) enabled switchable molecular recognition. The adsorption processes obeyed Langmuir isotherm and pseudo-second-order kinetic models. High recognition selectivity of the MIPs toward E2 was achieved over its structural analogues, and good reusability was displayed over 86% recovery after six adsorption-desorption cycles. Accordingly, the E2-MIPs were empolyed as new adsorbents for selective dispersive solid-phase extraction of E2, and offered low limits of detection and quantification of 4.81 and 16.03 mu g/L, respectively. Recoveries from goat milk samples ranged from 76.2% to 89.7% with the precisions (relative standard deviations, n = 3, %) of 2.8-3.7% at 30 degrees C. The intelligent E2-MIPs combining good adsorption, special recognition and temperature sensitivity proved to be a promising alternative to the selective identification and controlled extraction/removal of E2 in complicated samples by simple temperature-responsive regulation.
文章类型	Article
资助机构	National Natural Science Foundation of China(21477160, 21667018, 31660482) ; National Defense Science and Technology Innovation Project of Chinese Academy of Sciences(CXJJ-16M254)
收录类别	SCI
语种	英语
关键词[WOS]	SOLID-PHASE EXTRACTION ; BISPHENOL-A ; LIQUID-CHROMATOGRAPHY ; ENVIRONMENTAL WATER ; PHENOLIC-COMPOUNDS ; MILK SAMPLES ; 17-BETA-ESTRADIOL ; SURFACE ; TEMPERATURE ; PERFORMANCE
研究领域[WOS]	Chemistry
WOS记录号	WOS:000412610100025
引用统计	被引频次：42[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.yic.ac.cn/handle/133337/23462
专题	中国科学院海岸带环境过程与生态修复重点实验室
通讯作者	Xiong, Hua; Chen, Lingxin; Xiong, Hua(Nanchang Univ, State Key Lab Food Sci & Technol, Nanchang 330047, Jiangxi, Peoples R China); Chen, Lingxin(Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China)
作者单位	1.Nanchang Univ, State Key Lab Food Sci & Technol, Nanchang 330047, Jiangxi, Peoples R China 2.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China 3.Nanchang Univ, Sch Resources Environm & Chem Engn, Nanchang 330031, Jiangxi, Peoples R China 4.Binzhou Med Univ, Sch Pharm, Yantai 264003, Peoples R China
推荐引用方式 GB/T 7714	Xiong, Huihuang,Wu, Xiaqing,Lu, Wenhui,et al. Switchable zipper-like thermoresponsive molecularly imprinted polymers for selective recognition and extraction of estradiol[J]. TALANTA,2018,176:187-194.
APA	Xiong, Huihuang.,Wu, Xiaqing.,Lu, Wenhui.,Fu, Junqing.,Peng, Hailong.,...&Chen, Lingxin.(2018).Switchable zipper-like thermoresponsive molecularly imprinted polymers for selective recognition and extraction of estradiol.TALANTA,176,187-194.
MLA	Xiong, Huihuang,et al."Switchable zipper-like thermoresponsive molecularly imprinted polymers for selective recognition and extraction of estradiol".TALANTA 176(2018):187-194.