Citrifelins A and B, Citrinin Adducts with a Tetracyclic Framework from Cocultures of Marine-Derived Isolates of Penicillium citrinum and Beauveria felina
Meng, LH; Liu, Y; Li, XM; Xu, GM; Ji, NY; Wang, BG; Ji, NY (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Chunhui Rd 17, Yantai 264003, Peoples R China. nyji@yic.ac.cn; wangbg@ms.qdio.ac.cn
发表期刊JOURNAL OF NATURAL PRODUCTS
ISSN0163-3864
2015-09-01
卷号78期号:9页码:2301-2305
DOI10.1021/acs.jnatprod.5b00450
产权排序[Meng, Ling-Hong; Liu, Yang; Li, Xiao-Ming; Xu, Gang-Ming; Wang, Bin-Gui] Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China; [Meng, Ling-Hong; Liu, Yang] Univ Chinese Acad Sci, Beijing 100049, Peoples R China; [Ji, Nai-Yun] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China
作者部门海岸带生物学与生物资源利用所重点实验室
英文摘要Citrifelins A (1) and B (2), two citrinin adducts possessing a unique tetracyclic framework, were characterized from a coculture of marine-derived fungal isolates of Penicillium citrinum and Beauveria felina. Neither fungus produced these compounds when cultured alone under the same conditions. The structures of these adducts were elucidated on the basis of spectroscopic analysis, and the absolute configurations were assigned on the basis of TDDFT-ECD calculations. A hypothesis that adducts 1 and 2 might be derived from a citrinin derivative through a non-pericyclic Michael reaction is proposed. Compounds 1, 2, and 5 showed inhibitory activities against several human and aquatic pathogens.; Citrifelins A (1) and B (2), two citrinin adducts possessing a unique tetracyclic framework, were characterized from a coculture of marine-derived fungal isolates of Penicillium citrinum and Beauveria felina. Neither fungus produced these compounds when cultured alone under the same conditions. The structures of these adducts were elucidated on the basis of spectroscopic analysis, and the absolute configurations were assigned on the basis of TDDFT-ECD calculations. A hypothesis that adducts 1 and 2 might be derived from a citrinin derivative through a non-pericyclic Michael reaction is proposed. Compounds 1, 2, and 5 showed inhibitory activities against several human and aquatic pathogens.
文章类型Article
收录类别SCI
语种英语
关键词[WOS]NATURAL-PRODUCTS
研究领域[WOS]Plant Sciences ; Pharmacology & Pharmacy
WOS记录号WOS:000362056200021
引用统计
被引频次:49[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cn/handle/133337/9759
专题海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室
通讯作者Ji, NY (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Chunhui Rd 17, Yantai 264003, Peoples R China. nyji@yic.ac.cn; wangbg@ms.qdio.ac.cn
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GB/T 7714
Meng, LH,Liu, Y,Li, XM,et al. Citrifelins A and B, Citrinin Adducts with a Tetracyclic Framework from Cocultures of Marine-Derived Isolates of Penicillium citrinum and Beauveria felina[J]. JOURNAL OF NATURAL PRODUCTS,2015,78(9):2301-2305.
APA Meng, LH.,Liu, Y.,Li, XM.,Xu, GM.,Ji, NY.,...&wangbg@ms.qdio.ac.cn.(2015).Citrifelins A and B, Citrinin Adducts with a Tetracyclic Framework from Cocultures of Marine-Derived Isolates of Penicillium citrinum and Beauveria felina.JOURNAL OF NATURAL PRODUCTS,78(9),2301-2305.
MLA Meng, LH,et al."Citrifelins A and B, Citrinin Adducts with a Tetracyclic Framework from Cocultures of Marine-Derived Isolates of Penicillium citrinum and Beauveria felina".JOURNAL OF NATURAL PRODUCTS 78.9(2015):2301-2305.
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