YIC-IR  > 中科院海岸带环境过程与生态修复重点实验室
Fluorescent Probes for Hydrogen Sulfide Detection
Gao Min1,2; Yu Fabiao1; Chen Lingxin1; Chen, LX (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol Shandong, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China. lxchen@yic.ac.cn
2014-06-01
Source PublicationPROGRESS IN CHEMISTRY
ISSN1005-281X
Volume26Issue:6Pages:1065-1078
Contribution Rank[Gao Min; Yu Fabiao; Chen Lingxin] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol Shandong, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China; [Gao Min] Qufu Normal Univ, Coll Chem & Chem Engn, Qufu 273165, Peoples R China
AbstractFollowing carbon monoxide and nitric oxide, hydrogen sulfide (H2S) is found to be the third endogenous gasotransmitter, which provides the regulation significance of physiological and pathological processes in the cardiovascular and nervous systems. Therefore, the selective recognition and detection of H2S are of importance. Fluorescent probe method, among biological detection technologies, is an indispensable technique for the biological species analysis, and that is highlighted by its good selectivity, high sensitivity, noninvasive detection, and real-time monitoring in situ. Recently, the development of fluorescent probes for intracellular H2S detection has been becoming one of the hot topics. Herein, the progress during the last three years of fluorescent molecular probes based on the small molecules for H2S detection are reviewed. These fluorescent probes are classified and concluded according to the different types of chemical reaction with H2S, and then arranged specifically by the fluorophores in different type. The design concepts of molecular structures, detection mechanism and biological applications of these probes are introduced. In addition, the relationship between molecular structures and properties while testing are elucidated. Finally, the challenge and application prospects for the development of hydrogen sulfide fluorescent probes are also discussed.; Following carbon monoxide and nitric oxide, hydrogen sulfide (H2S) is found to be the third endogenous gasotransmitter, which provides the regulation significance of physiological and pathological processes in the cardiovascular and nervous systems. Therefore, the selective recognition and detection of H2S are of importance. Fluorescent probe method, among biological detection technologies, is an indispensable technique for the biological species analysis, and that is highlighted by its good selectivity, high sensitivity, noninvasive detection, and real-time monitoring in situ. Recently, the development of fluorescent probes for intracellular H2S detection has been becoming one of the hot topics. Herein, the progress during the last three years of fluorescent molecular probes based on the small molecules for H2S detection are reviewed. These fluorescent probes are classified and concluded according to the different types of chemical reaction with H2S, and then arranged specifically by the fluorophores in different type. The design concepts of molecular structures, detection mechanism and biological applications of these probes are introduced. In addition, the relationship between molecular structures and properties while testing are elucidated. Finally, the challenge and application prospects for the development of hydrogen sulfide fluorescent probes are also discussed.
KeywordHydrogen Sulfide Fluorescent Molecular Probe Reactive Sulfur Species Gasotransmitter Visual Detection
Department中科院海岸带环境过程与生态修复重点实验室
Subject AreaChemistry, Multidisciplinary
DOI10.7536/PC131155
Funding OrganizationChemistry
Indexed BySCI
WOS KeywordTURN-ON PROBE ; LIVING CELLS ; IN-VIVO ; HIGH SELECTIVITY ; H2S PRODUCTION ; REDOX CYCLE ; SE-BODIPY ; SENSOR ; RECOGNITION ; BISULFITE
SubtypeReview
Language英语
WOS Research AreaChemistry
WOS IDWOS:000338393000015
Citation statistics
Cited Times:8[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.yic.ac.cn/handle/133337/8739
Collection中科院海岸带环境过程与生态修复重点实验室
Corresponding AuthorChen, LX (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol Shandong, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China. lxchen@yic.ac.cn
Affiliation1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol Shandong, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China
2.Qufu Normal Univ, Coll Chem & Chem Engn, Qufu 273165, Peoples R China
First Author AffilicationYantai Institute of Coastal Zone Research, Chinese Academy of Sciences
Recommended Citation
GB/T 7714
Gao Min,Yu Fabiao,Chen Lingxin,et al. Fluorescent Probes for Hydrogen Sulfide Detection[J]. PROGRESS IN CHEMISTRY,2014,26(6):1065-1078.
APA Gao Min,Yu Fabiao,Chen Lingxin,&Chen, LX .(2014).Fluorescent Probes for Hydrogen Sulfide Detection.PROGRESS IN CHEMISTRY,26(6),1065-1078.
MLA Gao Min,et al."Fluorescent Probes for Hydrogen Sulfide Detection".PROGRESS IN CHEMISTRY 26.6(2014):1065-1078.
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