Institutional Repository of Key Laboratory of Coastal Zone Environmental Processes, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences (KLCEP)
| Fluorescent Probes for Hydrogen Sulfide Detection | |
Gao Min1,2; Yu Fabiao1; Chen Lingxin1 ; Chen, LX (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol Shandong, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China. lxchen@yic.ac.cn
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| 发表期刊 | PROGRESS IN CHEMISTRY
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| ISSN | 1005-281X |
| 2014-06-01 | |
| 卷号 | 26期号:6页码:1065-1078 |
| 关键词 | Hydrogen Sulfide Fluorescent Molecular Probe Reactive Sulfur Species Gasotransmitter Visual Detection |
| DOI | 10.7536/PC131155 |
| 产权排序 | [Gao Min; Yu Fabiao; Chen Lingxin] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol Shandong, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China; [Gao Min] Qufu Normal Univ, Coll Chem & Chem Engn, Qufu 273165, Peoples R China |
| 作者部门 | 中科院海岸带环境过程与生态修复重点实验室 |
| 英文摘要 | Following carbon monoxide and nitric oxide, hydrogen sulfide (H2S) is found to be the third endogenous gasotransmitter, which provides the regulation significance of physiological and pathological processes in the cardiovascular and nervous systems. Therefore, the selective recognition and detection of H2S are of importance. Fluorescent probe method, among biological detection technologies, is an indispensable technique for the biological species analysis, and that is highlighted by its good selectivity, high sensitivity, noninvasive detection, and real-time monitoring in situ. Recently, the development of fluorescent probes for intracellular H2S detection has been becoming one of the hot topics. Herein, the progress during the last three years of fluorescent molecular probes based on the small molecules for H2S detection are reviewed. These fluorescent probes are classified and concluded according to the different types of chemical reaction with H2S, and then arranged specifically by the fluorophores in different type. The design concepts of molecular structures, detection mechanism and biological applications of these probes are introduced. In addition, the relationship between molecular structures and properties while testing are elucidated. Finally, the challenge and application prospects for the development of hydrogen sulfide fluorescent probes are also discussed.; Following carbon monoxide and nitric oxide, hydrogen sulfide (H2S) is found to be the third endogenous gasotransmitter, which provides the regulation significance of physiological and pathological processes in the cardiovascular and nervous systems. Therefore, the selective recognition and detection of H2S are of importance. Fluorescent probe method, among biological detection technologies, is an indispensable technique for the biological species analysis, and that is highlighted by its good selectivity, high sensitivity, noninvasive detection, and real-time monitoring in situ. Recently, the development of fluorescent probes for intracellular H2S detection has been becoming one of the hot topics. Herein, the progress during the last three years of fluorescent molecular probes based on the small molecules for H2S detection are reviewed. These fluorescent probes are classified and concluded according to the different types of chemical reaction with H2S, and then arranged specifically by the fluorophores in different type. The design concepts of molecular structures, detection mechanism and biological applications of these probes are introduced. In addition, the relationship between molecular structures and properties while testing are elucidated. Finally, the challenge and application prospects for the development of hydrogen sulfide fluorescent probes are also discussed. |
| 文章类型 | Review |
| 资助机构 | Chemistry |
| 收录类别 | SCI |
| 语种 | 英语 |
| 关键词[WOS] | TURN-ON PROBE ; LIVING CELLS ; IN-VIVO ; HIGH SELECTIVITY ; H2S PRODUCTION ; REDOX CYCLE ; SE-BODIPY ; SENSOR ; RECOGNITION ; BISULFITE |
| 研究领域[WOS] | Chemistry |
| WOS记录号 | WOS:000338393000015 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.yic.ac.cn/handle/133337/8739 |
| 专题 | 中国科学院海岸带环境过程与生态修复重点实验室 |
| 通讯作者 | Chen, LX (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol Shandong, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China. lxchen@yic.ac.cn |
| 作者单位 | 1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol Shandong, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China 2.Qufu Normal Univ, Coll Chem & Chem Engn, Qufu 273165, Peoples R China |
| 推荐引用方式 GB/T 7714 | Gao Min,Yu Fabiao,Chen Lingxin,et al. Fluorescent Probes for Hydrogen Sulfide Detection[J]. PROGRESS IN CHEMISTRY,2014,26(6):1065-1078. |
| APA | Gao Min,Yu Fabiao,Chen Lingxin,&Chen, LX .(2014).Fluorescent Probes for Hydrogen Sulfide Detection.PROGRESS IN CHEMISTRY,26(6),1065-1078. |
| MLA | Gao Min,et al."Fluorescent Probes for Hydrogen Sulfide Detection".PROGRESS IN CHEMISTRY 26.6(2014):1065-1078. |
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