Two new withanolides from the halophyte Datura stramonium L.
Fang, Sheng-Tao1; Liu, Xia1,2; Kong, Na-Na1,2; Liu, Su-Jing1; Xia, Chuan-Hai1; Xia, CH (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Biol Resources Utilizat, Yantai 264003, Peoples R China. chxia@yic.ac.cn
Source PublicationNATURAL PRODUCT RESEARCH
ISSN1478-6419
2013-11-01
Volume27Issue:21Pages:1965-1970
KeywordDatura Stramonium Halophyte Withanolides Steroids
DOI10.1080/14786419.2013.800981
Contribution Rank[Fang, Sheng-Tao; Liu, Xia; Kong, Na-Na; Liu, Su-Jing; Xia, Chuan-Hai] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Biol Resources Utilizat, Yantai 264003, Peoples R China; [Liu, Xia; Kong, Na-Na] Univ Chinese Acad Sci, Coll Resources & Environm, Beijing 100049, Peoples R China
AbstractEight steroids, including five withanolides (1-5) and three other ergostane-type steroids (6-8), were isolated from the aerial parts of the halophyte Datura stramonium L., which were collected from the Yellow River Delta in China. Their structures were elucidated on the basis of extensive spectroscopic methods, especially 1D and 2D NMR techniques. Compounds 1 and 2 were new compounds and characterised as (22R)-27-hydroxy-7-methoxy-1-oxowitha-3,5,24-trienolide and its 27-O--d-glucopyranoside. Compound 3 was a new natural product and identified as (22R)-27-hydroxy-1-oxowitha-2,5,24-trienolide and isolated from nature for the first time.; Eight steroids, including five withanolides (1-5) and three other ergostane-type steroids (6-8), were isolated from the aerial parts of the halophyte Datura stramonium L., which were collected from the Yellow River Delta in China. Their structures were elucidated on the basis of extensive spectroscopic methods, especially 1D and 2D NMR techniques. Compounds 1 and 2 were new compounds and characterised as (22R)-27-hydroxy-7-methoxy-1-oxowitha-3,5,24-trienolide and its 27-O--d-glucopyranoside. Compound 3 was a new natural product and identified as (22R)-27-hydroxy-1-oxowitha-2,5,24-trienolide and isolated from nature for the first time.
SubtypeArticle
Indexed BySCI
Language英语
WOS Research AreaChemistry ; Pharmacology & Pharmacy
Funding Project海岸带生物学与生物资源利用所重点实验室
WOS IDWOS:000327834100005
Citation statistics
Cited Times:18[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.yic.ac.cn/handle/133337/7043
Collection海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室
Corresponding AuthorXia, CH (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Biol Resources Utilizat, Yantai 264003, Peoples R China. chxia@yic.ac.cn
Affiliation1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Biol Resources Utilizat, Yantai 264003, Peoples R China
2.Univ Chinese Acad Sci, Coll Resources & Environm, Beijing 100049, Peoples R China
Recommended Citation
GB/T 7714
Fang, Sheng-Tao,Liu, Xia,Kong, Na-Na,et al. Two new withanolides from the halophyte Datura stramonium L.[J]. NATURAL PRODUCT RESEARCH,2013,27(21):1965-1970.
APA Fang, Sheng-Tao,Liu, Xia,Kong, Na-Na,Liu, Su-Jing,Xia, Chuan-Hai,&Xia, CH .(2013).Two new withanolides from the halophyte Datura stramonium L..NATURAL PRODUCT RESEARCH,27(21),1965-1970.
MLA Fang, Sheng-Tao,et al."Two new withanolides from the halophyte Datura stramonium L.".NATURAL PRODUCT RESEARCH 27.21(2013):1965-1970.
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