Two new withanolides from the halophyte Datura stramonium L.
Fang, Sheng-Tao1; Liu, Xia1,2; Kong, Na-Na1,2; Liu, Su-Jing1; Xia, Chuan-Hai1; Xia, CH (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Biol Resources Utilizat, Yantai 264003, Peoples R China. chxia@yic.ac.cn
发表期刊NATURAL PRODUCT RESEARCH
ISSN1478-6419
2013-11-01
卷号27期号:21页码:1965-1970
关键词Datura Stramonium Halophyte Withanolides Steroids
DOI10.1080/14786419.2013.800981
产权排序[Fang, Sheng-Tao; Liu, Xia; Kong, Na-Na; Liu, Su-Jing; Xia, Chuan-Hai] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Biol Resources Utilizat, Yantai 264003, Peoples R China; [Liu, Xia; Kong, Na-Na] Univ Chinese Acad Sci, Coll Resources & Environm, Beijing 100049, Peoples R China
英文摘要Eight steroids, including five withanolides (1-5) and three other ergostane-type steroids (6-8), were isolated from the aerial parts of the halophyte Datura stramonium L., which were collected from the Yellow River Delta in China. Their structures were elucidated on the basis of extensive spectroscopic methods, especially 1D and 2D NMR techniques. Compounds 1 and 2 were new compounds and characterised as (22R)-27-hydroxy-7-methoxy-1-oxowitha-3,5,24-trienolide and its 27-O--d-glucopyranoside. Compound 3 was a new natural product and identified as (22R)-27-hydroxy-1-oxowitha-2,5,24-trienolide and isolated from nature for the first time.; Eight steroids, including five withanolides (1-5) and three other ergostane-type steroids (6-8), were isolated from the aerial parts of the halophyte Datura stramonium L., which were collected from the Yellow River Delta in China. Their structures were elucidated on the basis of extensive spectroscopic methods, especially 1D and 2D NMR techniques. Compounds 1 and 2 were new compounds and characterised as (22R)-27-hydroxy-7-methoxy-1-oxowitha-3,5,24-trienolide and its 27-O--d-glucopyranoside. Compound 3 was a new natural product and identified as (22R)-27-hydroxy-1-oxowitha-2,5,24-trienolide and isolated from nature for the first time.
文章类型Article
收录类别SCI
语种英语
研究领域[WOS]Chemistry ; Pharmacology & Pharmacy
WOS记录号WOS:000327834100005
引用统计
被引频次:25[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cn/handle/133337/7043
专题海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室
通讯作者Xia, CH (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Biol Resources Utilizat, Yantai 264003, Peoples R China. chxia@yic.ac.cn
作者单位1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Biol Resources Utilizat, Yantai 264003, Peoples R China
2.Univ Chinese Acad Sci, Coll Resources & Environm, Beijing 100049, Peoples R China
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GB/T 7714
Fang, Sheng-Tao,Liu, Xia,Kong, Na-Na,et al. Two new withanolides from the halophyte Datura stramonium L.[J]. NATURAL PRODUCT RESEARCH,2013,27(21):1965-1970.
APA Fang, Sheng-Tao,Liu, Xia,Kong, Na-Na,Liu, Su-Jing,Xia, Chuan-Hai,&Xia, CH .(2013).Two new withanolides from the halophyte Datura stramonium L..NATURAL PRODUCT RESEARCH,27(21),1965-1970.
MLA Fang, Sheng-Tao,et al."Two new withanolides from the halophyte Datura stramonium L.".NATURAL PRODUCT RESEARCH 27.21(2013):1965-1970.
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