| Meroterpenoid and Diphenyl Ether Derivatives from Penicillium sp MA-37, a Fungus Isolated from Marine Mangrove Rhizospheric Soil | |
Zhang, Yi2,3; Li, Xiao-Ming2; Shang, Zhuo2; Li, Chun-Shun2; Ji, Nai-Yun1 ; Wang, Bin-Gui2
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| 发表期刊 | JOURNAL OF NATURAL PRODUCTS
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| ISSN | 0163-3864 |
| 2012-11-01 | |
| 卷号 | 75期号:11页码:1888-1895 |
| 关键词 | Anthraquinone Derivatives Eurotium-rubrum Metabolites |
| 产权排序 | [Ji, Nai-Yun] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China; [Zhang, Yi; Li, Xiao-Ming; Shang, Zhuo; Li, Chun-Shun; Wang, Bin-Gui] Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China; [Zhang, Yi] Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China |
| 通讯作者 | Ji, NY (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Chunhui Rd 17, Yantai 264003, Peoples R China. |
| 作者部门 | 海岸带生物学与生物资源利用所重点实验室 |
| 英文摘要 | Penicillium sp. MA-37, which was obtained from the rhizospheric soil of the mangrove plant Bruguiera gymnorrhiza, exhibited different chemical profiles in static and shaken fermentation modes. Three new meroterpenoid derivatives, 4,25-dehydrominiolutelide B (1), 4,25-dehydro-22-deoxyminiolutelide B (2), and isominiolutelide A (3), together with three known ones were characterized from its static fermentation, while three new diphenyl ether derivatives, namely, Delta(1',3')-1'-dehydroxypenicillide (4), 7-O-acetylsecopenicillide C (5), and hydroxytenellic acid B (6), along with five related metabolites were isolated from the shaken culture. The structures of these compounds were elucidated on the basis of spectroscopic analysis, and the structure of compound 2 was confirmed by X-ray crystallographic analysis. The absolute configurations of 1-3 and 6 were determined by ECD and modified Mosher's method, respectively. All isolated compounds were evaluated for brine shrimp lethality and antibacterial activity.; Penicillium sp. MA-37, which was obtained from the rhizospheric soil of the mangrove plant Bruguiera gymnorrhiza, exhibited different chemical profiles in static and shaken fermentation modes. Three new meroterpenoid derivatives, 4,25-dehydrominiolutelide B (1), 4,25-dehydro-22-deoxyminiolutelide B (2), and isominiolutelide A (3), together with three known ones were characterized from its static fermentation, while three new diphenyl ether derivatives, namely, Delta(1',3')-1'-dehydroxypenicillide (4), 7-O-acetylsecopenicillide C (5), and hydroxytenellic acid B (6), along with five related metabolites were isolated from the shaken culture. The structures of these compounds were elucidated on the basis of spectroscopic analysis, and the structure of compound 2 was confirmed by X-ray crystallographic analysis. The absolute configurations of 1-3 and 6 were determined by ECD and modified Mosher's method, respectively. All isolated compounds were evaluated for brine shrimp lethality and antibacterial activity. |
| 文章类型 | Article |
| 资助机构 | Natural Science Foundation of China [30910103914, 30970293]; Ministry of Science and Technology of China [2010CB833800] |
| 收录类别 | SCI ; IC |
| 语种 | 英语 |
| 关键词[WOS] | ANTHRAQUINONE DERIVATIVES ; EUROTIUM-RUBRUM ; METABOLITES |
| 研究领域[WOS] | Plant Sciences ; Pharmacology & Pharmacy |
| WOS记录号 | WOS:000311461300003 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.yic.ac.cn/handle/133337/6118 |
| 专题 | 海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室 |
| 作者单位 | 1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 3.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Yi,Li, Xiao-Ming,Shang, Zhuo,et al. Meroterpenoid and Diphenyl Ether Derivatives from Penicillium sp MA-37, a Fungus Isolated from Marine Mangrove Rhizospheric Soil[J]. JOURNAL OF NATURAL PRODUCTS,2012,75(11):1888-1895. |
| APA | Zhang, Yi,Li, Xiao-Ming,Shang, Zhuo,Li, Chun-Shun,Ji, Nai-Yun,&Wang, Bin-Gui.(2012).Meroterpenoid and Diphenyl Ether Derivatives from Penicillium sp MA-37, a Fungus Isolated from Marine Mangrove Rhizospheric Soil.JOURNAL OF NATURAL PRODUCTS,75(11),1888-1895. |
| MLA | Zhang, Yi,et al."Meroterpenoid and Diphenyl Ether Derivatives from Penicillium sp MA-37, a Fungus Isolated from Marine Mangrove Rhizospheric Soil".JOURNAL OF NATURAL PRODUCTS 75.11(2012):1888-1895. |
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