| Two New Epoxysteroids from Helianthus tuberosus | |
Li, Xiao-Dong; Miao, Feng-Ping ; Ji, Nai-Yun
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| 发表期刊 | MOLECULES
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| ISSN | 1420-3049 |
| 2011-10-01 | |
| 卷号 | 16期号:10页码:8646-8653 |
| 关键词 | Helianthus Tuberosus Steroid 5 Alpha 8 Alpha-epidioxy-22 Beta 5 Alpha 23 Beta-epoxyergosta-6-en-3 Beta-ol 8 Alpha-epidioxy-22 Alpha 23 Alpha-epoxyergosta-6-en-3 Beta-ol |
| 产权排序 | [Li, Xiao-Dong; Miao, Feng-Ping; Ji, Nai-Yun] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China |
| 通讯作者 | Ji, NY (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China |
| 作者部门 | 生物资源实验室 |
| 英文摘要 | Two new epoxy steroids, 5 alpha,8 alpha-epidioxy-22 beta,23 beta-epoxyergosta-6-en-3 beta-ol (1) and 5 alpha,8 alpha-epidioxy-22 alpha,23 alpha-epoxyergosta-6-en-3 beta-ol (2), and ten known steroids including (24R)-5 alpha,8 alpha-epidioxyergosta-6-en-3 beta-ol (3), (22E,24R)-5 alpha,8 alpha-epidioxyergosta-6,22-dien-3 beta-ol (4), (22E, 24R)-5 alpha,8 alpha-epidioxyergosta-6,9(11), 22-trien-3 beta-ol (5), beta-sitosterol (6), sitost-5-en-3 beta-ol acetate (7), 7 alpha-hydroxysitosterol (8), schleicheol 2 (9), (24R)-24-ethyl-5 alpha-cholestane-3 beta,5 alpha,6 beta-triol (10), 7 alpha-hydroxystigmasterol (11), and stigmasterol (12) were isolated from Helianthus tuberosus grown in Laizhou salinized land of coastal zone of Bohai Sea, China. The structures of these compounds were unambiguously established by 1D, 2D NMR and mass spectroscopic techniques. The new compounds 1 and 2 exhibited weak antibacterial activity and no antifungal activity.; Two new epoxy steroids, 5 alpha,8 alpha-epidioxy-22 beta,23 beta-epoxyergosta-6-en-3 beta-ol (1) and 5 alpha,8 alpha-epidioxy-22 alpha,23 alpha-epoxyergosta-6-en-3 beta-ol (2), and ten known steroids including (24R)-5 alpha,8 alpha-epidioxyergosta-6-en-3 beta-ol (3), (22E,24R)-5 alpha,8 alpha-epidioxyergosta-6,22-dien-3 beta-ol (4), (22E, 24R)-5 alpha,8 alpha-epidioxyergosta-6,9(11), 22-trien-3 beta-ol (5), beta-sitosterol (6), sitost-5-en-3 beta-ol acetate (7), 7 alpha-hydroxysitosterol (8), schleicheol 2 (9), (24R)-24-ethyl-5 alpha-cholestane-3 beta,5 alpha,6 beta-triol (10), 7 alpha-hydroxystigmasterol (11), and stigmasterol (12) were isolated from Helianthus tuberosus grown in Laizhou salinized land of coastal zone of Bohai Sea, China. The structures of these compounds were unambiguously established by 1D, 2D NMR and mass spectroscopic techniques. The new compounds 1 and 2 exhibited weak antibacterial activity and no antifungal activity. |
| 文章类型 | Article |
| 资助机构 | Yantai Municipal Sci-Tech Development Program[2009164]; Chinese Academy of Sciences for Key Topics in Innovation Engineering[KZCX2-YW-225, KZCX2-YW-QN209]; Foundation of the Chinese Academy of Sciences |
| 收录类别 | SCI |
| 语种 | 英语 |
| 关键词[WOS] | JERUSALEM-ARTICHOKE ; STEROLS |
| 研究领域[WOS] | Chemistry |
| WOS记录号 | WOS:000296973000035 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.yic.ac.cn/handle/133337/5364 |
| 专题 | 海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室 |
| 作者单位 | Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Xiao-Dong,Miao, Feng-Ping,Ji, Nai-Yun. Two New Epoxysteroids from Helianthus tuberosus[J]. MOLECULES,2011,16(10):8646-8653. |
| APA | Li, Xiao-Dong,Miao, Feng-Ping,&Ji, Nai-Yun.(2011).Two New Epoxysteroids from Helianthus tuberosus.MOLECULES,16(10),8646-8653. |
| MLA | Li, Xiao-Dong,et al."Two New Epoxysteroids from Helianthus tuberosus".MOLECULES 16.10(2011):8646-8653. |
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