Molecular Evolution of Lycopene Cyclases Involved in the Formation of Carotenoids in Eukaryotic Algae | |
Cui, Hongli1,2; Wang, Yinchu1,2; Qin, Song1 | |
发表期刊 | PLANT MOLECULAR BIOLOGY REPORTER |
ISSN | 0735-9640 |
2011-12-01 | |
卷号 | 29期号:4页码:1013-1020 |
关键词 | Carotenoid Biosynthesis Lycopene Cyclase Molecular Evolution Coevolution Algae |
产权排序 | [Cui, Hongli; Wang, Yinchu; Qin, Song] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China; [Cui, Hongli; Wang, Yinchu] Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China |
通讯作者 | Qin, S (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China |
作者部门 | 生物资源实验室 |
英文摘要 | Carotenoids play crucial roles in structure and function of the photosynthetic apparatus of bacteria, algae, and higher plants. The formation of carotenoids from lycopene is catalyzed by the enzyme lycopene cyclase (LCY), which is structurally and functionally conserved in all organisms. A comparative genomic analysis regarding the LCY revealed that the higher plant (Arabidopsis thaliana) and the green alga (Ostreococcus sp. RCC809, Ostreococcus tauri, Ostreococcus lucimarinus, Micromonas sp. RCC299, Micromonas pusiua, Chlorella vulgaris, Volvox carteri, and Coccomyxa sp. C-169) possess two different LCY (beta- and epsilon-type). This indicated that an ancient gene duplication event must have occurred, which produced two classes of LCY in algae. However, some other green alga retained only one class of LCY, such as Haematococcus pluvialis (beta), Dunaliella salina (beta), Chlamydomonas reinhardtii (epsilon), and Chlorella sp. NC64A (epsilon), and the other gene copy was lost in these species. Furthermore, the similar LCY lost occurred in red alga (Cyanidioschyzon merolae) and Heterokontophyta (Phaeodactylum tricornutum and Thalassiosira pseudonana), which possess only the LCYB. In addition, the protein sequence of LCYB is highly similar to capsanthin-capsorubin synthase (CCS), which is another carotenogenic enzyme of plants. As a result, it is proposed that the CCS evolved from a duplicated LCYB. The discovery of two classes of LCY families in some algae suggests that carotenoid biosynthesis is differentially regulated in response to development and environmental stress in these algae, like members of LCY families are differentially regulated during development or stress in some higher plants.; Carotenoids play crucial roles in structure and function of the photosynthetic apparatus of bacteria, algae, and higher plants. The formation of carotenoids from lycopene is catalyzed by the enzyme lycopene cyclase (LCY), which is structurally and functionally conserved in all organisms. A comparative genomic analysis regarding the LCY revealed that the higher plant (Arabidopsis thaliana) and the green alga (Ostreococcus sp. RCC809, Ostreococcus tauri, Ostreococcus lucimarinus, Micromonas sp. RCC299, Micromonas pusiua, Chlorella vulgaris, Volvox carteri, and Coccomyxa sp. C-169) possess two different LCY (beta- and epsilon-type). This indicated that an ancient gene duplication event must have occurred, which produced two classes of LCY in algae. However, some other green alga retained only one class of LCY, such as Haematococcus pluvialis (beta), Dunaliella salina (beta), Chlamydomonas reinhardtii (epsilon), and Chlorella sp. NC64A (epsilon), and the other gene copy was lost in these species. Furthermore, the similar LCY lost occurred in red alga (Cyanidioschyzon merolae) and Heterokontophyta (Phaeodactylum tricornutum and Thalassiosira pseudonana), which possess only the LCYB. In addition, the protein sequence of LCYB is highly similar to capsanthin-capsorubin synthase (CCS), which is another carotenogenic enzyme of plants. As a result, it is proposed that the CCS evolved from a duplicated LCYB. The discovery of two classes of LCY families in some algae suggests that carotenoid biosynthesis is differentially regulated in response to development and environmental stress in these algae, like members of LCY families are differentially regulated during development or stress in some higher plants. |
文章类型 | Article |
资助机构 | National Natural Science Foundation of China[40876082]; International Innovation Partnership Program: Typical Environmental Process and Effects on Resources in Coastal Zone Area |
收录类别 | SCI |
语种 | 英语 |
关键词[WOS] | FUNCTIONAL-ANALYSIS ; GENE-TRANSFER ; ISOPRENOID BIOSYNTHESIS ; PHYTOENE SYNTHASE ; CRT GENES ; PLANTS ; PATHWAY ; PHYLOGENIES ; ENZYMES ; CLONING |
研究领域[WOS] | Biochemistry & Molecular Biology ; Plant Sciences |
WOS记录号 | WOS:000296068700027 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.yic.ac.cn/handle/133337/5354 |
专题 | 海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室 |
作者单位 | 1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China |
推荐引用方式 GB/T 7714 | Cui, Hongli,Wang, Yinchu,Qin, Song. Molecular Evolution of Lycopene Cyclases Involved in the Formation of Carotenoids in Eukaryotic Algae[J]. PLANT MOLECULAR BIOLOGY REPORTER,2011,29(4):1013-1020. |
APA | Cui, Hongli,Wang, Yinchu,&Qin, Song.(2011).Molecular Evolution of Lycopene Cyclases Involved in the Formation of Carotenoids in Eukaryotic Algae.PLANT MOLECULAR BIOLOGY REPORTER,29(4),1013-1020. |
MLA | Cui, Hongli,et al."Molecular Evolution of Lycopene Cyclases Involved in the Formation of Carotenoids in Eukaryotic Algae".PLANT MOLECULAR BIOLOGY REPORTER 29.4(2011):1013-1020. |
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