| Asporyergosterol, A New Steroid from an Algicolous Isolate of Aspergillus oryzae | |
Qiao, Ming-Feng1,2; Ji, Nai-Yun1 ; Liu, Xiang-Hong1; Li, Fang3; Xue, Qin-Zhao1
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| 发表期刊 | NATURAL PRODUCT COMMUNICATIONS
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| ISSN | 1934-578X |
| 2010-10-01 | |
| 卷号 | 5期号:10页码:1575-1578 |
| 关键词 | Asporyergosterol Red Alga Heterosiphonia Japonica Endophytic Fungus Aspergillus Oryzae |
| 产权排序 | [Qiao, Ming-Feng; Ji, Nai-Yun; Liu, Xiang-Hong; Xue, Qin-Zhao] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China; [Qiao, Ming-Feng] Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China; [Li, Fang] Qingdao Univ Sci & Technol, Qingdao 266042, Peoples R China |
| 通讯作者 | Ji, NY, Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China |
| 作者部门 | 生物资源实验室 |
| 英文摘要 | Asporyergosterol (1), a new steroid with an E double bond between C-17 and C-20, was identified from the culture extracts of Aspergillus oryzae, an endophytic fungus isolated from the marine red alga Heterosiphonia japonica. Moreover, four known steroids including (22E,24R)-ergosta-4,6,8(14),22-tetraen-3-one (2), (22E,24R)-3 beta-hydroxyergosta-5,8,22-trien-7-one (3), (22E,24R)-ergosta-7,22-dien-3 beta,5 alpha,6 beta-triol (4), and (22E,24R)-5 alpha,8 alpha-epidioxyergosta-6,22-dien-3 beta-ol (5) were isolated. Structures of these compounds were unambiguously established by spectroscopic techniques and by comparison with literature values. All the isolates exhibited low activity to modulate acetylcholinesterase (AChE).; Asporyergosterol (1), a new steroid with an E double bond between C-17 and C-20, was identified from the culture extracts of Aspergillus oryzae, an endophytic fungus isolated from the marine red alga Heterosiphonia japonica. Moreover, four known steroids including (22E,24R)-ergosta-4,6,8(14),22-tetraen-3-one (2), (22E,24R)-3 beta-hydroxyergosta-5,8,22-trien-7-one (3), (22E,24R)-ergosta-7,22-dien-3 beta,5 alpha,6 beta-triol (4), and (22E,24R)-5 alpha,8 alpha-epidioxyergosta-6,22-dien-3 beta-ol (5) were isolated. Structures of these compounds were unambiguously established by spectroscopic techniques and by comparison with literature values. All the isolates exhibited low activity to modulate acetylcholinesterase (AChE). |
| 文章类型 | Article |
| 资助机构 | Chinese Academy of Sciences for Key Topics in Innovation Engineering [KZCX2-YW-QN209, KSCX2-YW-G-073, KZCX2-YW-225]; Shandong Province Natural Science Foundation [ZR2009BQ021]; Yantai Municipal Sci-Tech Development Program [2009164]; Foundation of the Chinese Academy of Sciences |
| 收录类别 | SCI |
| 语种 | 英语 |
| 关键词[WOS] | FUNGI |
| 研究领域[WOS] | Pharmacology & Pharmacy ; Food Science & Technology |
| WOS记录号 | WOS:000283380800012 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.yic.ac.cn/handle/133337/3745 |
| 专题 | 海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室 中国科学院烟台海岸带研究所知识产出 |
| 作者单位 | 1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China 3.Qingdao Univ Sci & Technol, Qingdao 266042, Peoples R China |
| 推荐引用方式 GB/T 7714 | Qiao, Ming-Feng,Ji, Nai-Yun,Liu, Xiang-Hong,et al. Asporyergosterol, A New Steroid from an Algicolous Isolate of Aspergillus oryzae[J]. NATURAL PRODUCT COMMUNICATIONS,2010,5(10):1575-1578. |
| APA | Qiao, Ming-Feng,Ji, Nai-Yun,Liu, Xiang-Hong,Li, Fang,&Xue, Qin-Zhao.(2010).Asporyergosterol, A New Steroid from an Algicolous Isolate of Aspergillus oryzae.NATURAL PRODUCT COMMUNICATIONS,5(10),1575-1578. |
| MLA | Qiao, Ming-Feng,et al."Asporyergosterol, A New Steroid from an Algicolous Isolate of Aspergillus oryzae".NATURAL PRODUCT COMMUNICATIONS 5.10(2010):1575-1578. |
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