海藻寡糖的化学法降解制备技术研究进展

	海藻寡糖的化学法降解制备技术研究进展
其他题名	Application of alginate hydrogel as a delivery vehicle in tissue regeneration
	孙林 1,2; 宋宛霖 1,2; 钟志海 1,2; 刘正一1,2
发表期刊	大连工业大学学报
ISSN	1674-1404
	2023
卷号	42 期号:6 页码:427-433
关键词	海藻寡糖化学法降解规模化制备精准制
英文摘要	Alginate is a class of linear hydrophilic polysaccharides found in brown algae.It is composed of repeating units of D-mannuronic acid (M) and L-guluronic acid (G) in different proportions.It is one of the natural biological materials used for hydrogel synthesis.Through simple ion cross-linking,it can react with Ca~(2+) and other multivalent inorganic cations to form hydrogel,which called egg box reaction.There are a large number of-OH and-COOH polar groups on the alginate skeleton,which can be modified by chemical or physical methods to achieve controlled release of cells or biologically active molecules in response to temperature,pH,light and other stimuli.At present,one of the main application strategies in the field of tissue regeneration is to use biocompatible materials,combined with bioactive molecules and cells,to promote the regeneration of damaged tissues.Hydrogel materials have the potential to protect embedded cells and mimic the natural extracellular matrix.Alginate is also widely used in the field of tissue regeneration due to its easy gelation and good biocompatibility.In this review,we summarized the different crosslinking methods of alginate hydrogels,focusing on the characteristics of alginate hydrogels that are responsive to stimuli and their applications as delivery vehicles in tissue regeneration.
中文摘要	海藻寡糖是海藻多糖的降解产物,因其具有良好的溶解性和独特的生物活性,在食品、农业和医疗等领域具有广泛、重要的应用价值。综述了5种代表性海藻寡糖——褐藻胶寡糖(AOS)、岩藻寡糖(FOS)、琼胶寡糖(AGOS)、卡拉胶寡糖(COS)、浒苔寡糖(EOS)的化学法制备技术,并对海藻寡糖化学法降解制备技术的发展趋势进行了分析。
文章类型	期刊论文
收录类别	CSCD
语种	中文
CSCD记录号	CSCD:7176917
引用统计
文献类型	期刊论文
条目标识符	http://ir.yic.ac.cn/handle/133337/34094
专题	海岸带生物学与生物资源利用重点实验室海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室
作者单位	1.中国科学院烟台海岸带研究所,山东烟台264003; 2.中国科学院海洋大科学研究中心,山东青岛266071
推荐引用方式 GB/T 7714	孙林,宋宛霖,钟志海,等. 海藻寡糖的化学法降解制备技术研究进展[J]. 大连工业大学学报,2023,42(6):427-433.
APA	孙林,宋宛霖,钟志海,&刘正一.(2023).海藻寡糖的化学法降解制备技术研究进展.大连工业大学学报,42(6),427-433.
MLA	孙林,et al."海藻寡糖的化学法降解制备技术研究进展".大连工业大学学报 42.6(2023):427-433.