The present invention relates to the field of chemical and pharmaceutical industry, in particular is a chitosan triazine pyridine quaternary ammonium salt derivatives and its preparation method and application. Formula (1) is shown, wherein the n is the average value range 1035-1242. Preparing : three poly cyanogen chlorine in the pyridine in anhydrous second grade nitrile , for the 25 [...] to be generated under the condition of white precipitation reaction, the pyridine-substituted three poly cyanogen chlorine derivatives; said adding pyridine molar amount is of three poly cyanogen chlorine 1-2 times, get pyridine substituted three poly cyanogen chlorine derivatives with chitosan in 25-60 the reaction under the conditions of [...] 8-16h, wherein the pyridine-substituted three poly cyanogen chlorine adding the total number of moles of the monomer is chitosan 1-3 times, to obtain chitosan triazine pyridine quaternary ammonium salt derivatives. Stated chitosan triazine pyridine quaternary ammonium salt derivatives have bacteriostatic effects. The resulting derivatives of the present invention is good in water solubility, enhance the biological activity of the chitosan, to expand the application range of the chitosan, can be widely used in the field of medicine and agriculture.
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