The invention relates to the food field, the cosmetics field and the biomedicine industry, particularly to a high-oxidation-resistant phenolic chitosan Schiff base, a preparation method and applications thereof, wherein the phenol group-containing chitosan Schiff base is represented by a formula (1). According to the present invention, the method has advantages of simple reaction process, mild conditions and cheap and easily available reaction materials, and is suitable for promotion and industrial application; and the research results prove that the high-oxidation-resistant phenolic chitosan Schiff base has good water solubility and good anti-oxidation activity, enhances the biological activity of chitosan, expands the application range of chitosan, and can be widely applied in the fields of cosmetics, food and biomedicine. The formula (1) is defined in the specification.
; 李青
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