Genome-wide analysis of lectins in cyanobacteria: from evolutionary mode to motif patterns

doi:10.1186/s12864-023-09790-8

	Genome-wide analysis of lectins in cyanobacteria: from evolutionary mode to motif patterns
	Xu, Tongli 1,2; Cui, Yulin3 ; Qin, Song2,4 ; Wang, Yin-Chu2,4,5
发表期刊	BMC GENOMICS
ISSN	1471-2164
	2023-11-16
卷号	24 期号:1 页码:8
关键词	Lectin Gene family Evolution Cyanobacteria Motif
DOI	10.1186/s12864-023-09790-8
通讯作者	Qin, Song(sqin@yic.ac.cn) ; Wang, Yin-Chu(ycwang@yic.ac.cn)
英文摘要	Lectins are glycoproteins that can bind to specific carbohydrates, and different lectin families exhibit different biological activities. They are also present in the cyanobacteria and many of them have shown excellent therapeutic effect, which deserve for bioprospecting. However, in comparison to those from terrestrial plants, the current knowledge on cyanobacterial lectins is very limited. To this end, genome-wide analyses were performed to find out their evolutionary mode and motif patterns in 316 genomes of representative taxa. In results, 196 putative cyanobacterial lectins were dig out and 105 of them were classified into known families. Seven lectins were found to be belonged to distinct two lectin families, and they may have the potential activities of both lectin families. Whereas no MFP-2, Chitin, and Nictaba family lectins were found. What's more, the Legume lectin-like lectin family was found to be the richest and most complex in cyanobacteria, which could be a main research direction for future cyanobacterial lectin bioprospecting and development. Our classification and prediction of cyanobacteria lectins is expected to provide assistance in the development of lectin-based medicine and provide solutions to the current thorny viral and tumor diseases in humans.
资助机构	Not applicable.
收录类别	SCI
语种	英语
关键词[WOS]	ALGA EUCHEUMA-SERRA ; BINDING
研究领域[WOS]	Biotechnology & Applied Microbiology ; Genetics & Heredity
WOS记录号	WOS:001103440800002
引用统计
文献类型	期刊论文
条目标识符	http://ir.yic.ac.cn/handle/133337/33205
专题	海岸带生物学与生物资源利用重点实验室海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室
通讯作者	Qin, Song; Wang, Yin-Chu
作者单位	1.Shandong Univ Tradit Chinese Med, Jinan 250335, Peoples R China 2.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China 3.Binzhou Med Univ, Yantai 264003, Peoples R China 4.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao 266071, Peoples R China 5.Natl Basic Sci Data Ctr, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Xu, Tongli,Cui, Yulin,Qin, Song,et al. Genome-wide analysis of lectins in cyanobacteria: from evolutionary mode to motif patterns[J]. BMC GENOMICS,2023,24(1):8.
APA	Xu, Tongli,Cui, Yulin,Qin, Song,&Wang, Yin-Chu.(2023).Genome-wide analysis of lectins in cyanobacteria: from evolutionary mode to motif patterns.BMC GENOMICS,24(1),8.
MLA	Xu, Tongli,et al."Genome-wide analysis of lectins in cyanobacteria: from evolutionary mode to motif patterns".BMC GENOMICS 24.1(2023):8.