A dummy molecularly imprinted ratiometric fluorescence nanosensor for the sensitive detection of guanidyl-microcystins in environmental water

doi:10.1039/d2an01928k

	A dummy molecularly imprinted ratiometric fluorescence nanosensor for the sensitive detection of guanidyl-microcystins in environmental water
	Li, Ping 1; Fu, Hao 1; Bai, Zhenyu 1; Feng, Xiaoyang 1; Qi, Ji 2; Song, Xingliang 1; Hu, Xueping 1; Chen, Lingxin2,3
发表期刊	ANALYST
ISSN	0003-2654
	2023-01-03
页码	10
DOI	10.1039/d2an01928k
通讯作者	Song, Xingliang(xlssong@yeah.net) ; Hu, Xueping(xuephu@yeah.net)
英文摘要	An effective strategy is proposed to construct a highly sensitive ratiometric fluorescence sensing platform for microcystins (MCs) based on a dummy molecularly imprinted polymer using metformin as a template. The imprinted nanohybrids of carbon dots (CDs) combined with fluorescein isothiocyanate (FITC) are synthesized (CDs-FITC-SiO2@MIP), in which the CDs and FITC serve as assisted response signals and reference enhancement signals, respectively. Metformin can be used as a dummy template for MCs due to its partially similar molecular fragments to MCs that can form a specific recognition site cavity. MCs can simultaneously induce an obvious fluorescence quenching effect for the CDs and a reference fluorescence enhancement for FITC-SiO2, enabling ratiometric fluorescence detection of MCs. Thus, CDs-FITC-SiO2@MIP used as a signal probe has favorable sensitivity, stability, and selectivity. More importantly, a good linear relationship between the fluorescence intensity ratio (I-620/450) and the concentration of MCs in the range of 0.5-500 mu g L-1 is obtained with a LOD of 0.013 mu g L-1 and 0.022 mu g L-1 for MC-RR and MC-LR, respectively, under the optimum conditions. This method has great application potential in water quality monitoring by using CDs-FITC-SiO2@MIP as a promising candidate for monitoring MCs in complex systems.
资助机构	National Natural Science Foundation of China ; Natural Science Foundation of Shandong Province ; Key Research and Development Program of Linyi City
收录类别	SCI
语种	英语
关键词[WOS]	QUANTUM DOTS ; ULTRASENSITIVE DETECTION ; LR ; POLYMERS ; NANOPARTICLES ; RECOGNITION ; TOXINS ; TISSUE ; SENSOR ; FISH
研究领域[WOS]	Chemistry
WOS记录号	WOS:000906156800001
引用统计	被引频次：4[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.yic.ac.cn/handle/133337/32456
专题	中国科学院海岸带环境过程与生态修复重点实验室
通讯作者	Song, Xingliang; Hu, Xueping
作者单位	1.Linyi Univ, Sch Chem & Chem Engn, Linyi 276005, Peoples R China 2.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China 3.Binzhou Med Univ, Sch Pharm, Yantai 264003, Peoples R China
推荐引用方式 GB/T 7714	Li, Ping,Fu, Hao,Bai, Zhenyu,et al. A dummy molecularly imprinted ratiometric fluorescence nanosensor for the sensitive detection of guanidyl-microcystins in environmental water[J]. ANALYST,2023:10.
APA	Li, Ping.,Fu, Hao.,Bai, Zhenyu.,Feng, Xiaoyang.,Qi, Ji.,...&Chen, Lingxin.(2023).A dummy molecularly imprinted ratiometric fluorescence nanosensor for the sensitive detection of guanidyl-microcystins in environmental water.ANALYST,10.
MLA	Li, Ping,et al."A dummy molecularly imprinted ratiometric fluorescence nanosensor for the sensitive detection of guanidyl-microcystins in environmental water".ANALYST (2023):10.