Application of Tilapia Skin Acellular Dermal Matrix to Induce Acute Skin Wound Repair in Rats | |
Lv, Kangning1,2; Wang, Lei2![]() ![]() ![]() | |
发表期刊 | FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
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ISSN | 2296-4185 |
2022-02-14 | |
卷号 | 9页码:10 |
关键词 | tilapia skin acellular dermal matrix collagen wound repair |
DOI | 10.3389/fbioe.2021.792344 |
通讯作者 | Qin, Song(sqin@yic.ac.cn) |
英文摘要 | Extracellular matrix (ECM) material with good biological activity is essential to simulate cell growth microenvironment, induce cell infiltration and angiogenesis, and promote the repair of large area acute skin wound. In this study, tilapia skin acellular dermal matrix (TADM) was prepared to simulate ECM microenvironment, which can promote substantial area acute wound healing in rats. The main component of TADM is type I collagen, which has good physical and chemical properties, biological activity and cell adhesion. TADM is a form of biomaterial with low immunogenicity, low risk of prion infection and lower economic cost than other related materials such as mammalian collagen biomaterials. Our results show that TADM can guide cell infiltration, angiogenesis, regulate the expression and secretion of inflammatory and skin repair correlated factors to promote tissue healing. |
资助机构 | Department of Science and Technology of Shandong Province |
收录类别 | SCI |
语种 | 英语 |
关键词[WOS] | ARTIFICIAL SKIN ; COLLAGEN ; CARBODIIMIDE ; GRAFTS ; BURNS |
研究领域[WOS] | Biotechnology & Applied Microbiology ; Science & Technology - Other Topics |
WOS记录号 | WOS:000761695500001 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.yic.ac.cn/handle/133337/31505 |
专题 | 海岸带生物学与生物资源利用重点实验室 海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室 |
通讯作者 | Qin, Song |
作者单位 | 1.Yantai Univ, Sch Ocean, Yantai, Peoples R China 2.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai, Peoples R China 3.Yantai Univ, Sch Life Sci, Yantai, Peoples R China |
推荐引用方式 GB/T 7714 | Lv, Kangning,Wang, Lei,He, Xiaoli,et al. Application of Tilapia Skin Acellular Dermal Matrix to Induce Acute Skin Wound Repair in Rats[J]. FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY,2022,9:10. |
APA | Lv, Kangning,Wang, Lei,He, Xiaoli,Li, Wenjun,Han, Lei,&Qin, Song.(2022).Application of Tilapia Skin Acellular Dermal Matrix to Induce Acute Skin Wound Repair in Rats.FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY,9,10. |
MLA | Lv, Kangning,et al."Application of Tilapia Skin Acellular Dermal Matrix to Induce Acute Skin Wound Repair in Rats".FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY 9(2022):10. |
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