| Synthesis and antioxidant activity of the inulin derivative bearing 1,2,3-triazole and diphenyl phosphate | |
Wei, Lijie1,2,3; Sui, Haishan1; Zhang, Jingjing2,3; Guo, Zhanyong2,3,4
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| Source Publication | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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| ISSN | 0141-8130 |
| 2021-09-01 | |
| Volume | 186Pages:47-53 |
| Keyword | Inulin derivative Antioxidant activity CuAAC Click chemistry |
| DOI | 10.1016/j.ijbiomac.2021.06.148 |
| Corresponding Author | Guo, Zhanyong(zhanyongguo@hotmail.com) |
| Abstract | In this paper, the inulin derivative (3) bearing 1,2,3-triazole and diphenyl phosphate was successfully synthesized by CuAAC Click chemistry. Detailed structural characterization was determined using FTIR spectroscopy, H-1 NMR spectroscopy, C-13 NMR spectroscopy, and elemental analysis. The antioxidant activities against hydroxyl radicals, superoxide radicals, and DPPH radicals were estimated in vitro respectively. The results showed that the antioxidant activity of the inulin derivative (3) was significantly enhanced compared with inulin. The inulin derivative (3) exhibited stronger radical scavenging abilities, especially against hydroxyl radicals and superoxide radicals. The scavenging values of the inulin derivative (3) were 98.2% and 95.4% at 1.6 mg/mL against hydroxyl radicals and superoxide radicals respectively. Besides, the scavenging value of the inulin derivative (3) increased by about 40% to scavenge DPPH radicals at 1.6 mg/mL than inulin. The results showed that the inulin derivative (3) bearing 1,2,3-triazole and diphenyl phosphate exhibited tremendously enhanced antioxidant activity compared with inulin. The synthetic strategy might provide an effective way to prepare novel inulin antioxidant biomaterials. |
| Funding Organization | Youth Innovation Promotion Association CAS ; Natural Science Foundation of Shandong Province of China ; National Key Research and Development Pro-gram of China ; Natural Science Foundation of Shandong Province Science and Technology Development Plan |
| Indexed By | SCI |
| Language | 英语 |
| WOS Keyword | REACTIVE OXYGEN ; CHITOSAN DERIVATIVES ; ANTIFUNGAL ACTIVITY ; SCAVENGING ACTIVITY ; CLICK CHEMISTRY ; PHOSPHORYLATION ; COPOLYMERS ; NITROGEN ; STRESS |
| WOS Research Area | Biochemistry & Molecular Biology ; Chemistry ; Polymer Science |
| WOS ID | WOS:000688432800006 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.yic.ac.cn/handle/133337/29704 |
| Collection | 海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心 海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室 |
| Corresponding Author | Guo, Zhanyong |
| Affiliation | 1.Weifang Adm Market Regulat, Weifang Inspect & Testing Ctr, Weifang 261000, Shandong, Peoples R China 2.Chinese Acad Sci, Key Lab Coastal Biol & Bioresource Utilizat, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Chinese Acad Sci, Ctr Ocean Mega Sci, 7 Nanhai Rd, Qingdao 266071, Peoples R China |
| Recommended Citation GB/T 7714 | Wei, Lijie,Sui, Haishan,Zhang, Jingjing,et al. Synthesis and antioxidant activity of the inulin derivative bearing 1,2,3-triazole and diphenyl phosphate[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2021,186:47-53. |
| APA | Wei, Lijie,Sui, Haishan,Zhang, Jingjing,&Guo, Zhanyong.(2021).Synthesis and antioxidant activity of the inulin derivative bearing 1,2,3-triazole and diphenyl phosphate.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,186,47-53. |
| MLA | Wei, Lijie,et al."Synthesis and antioxidant activity of the inulin derivative bearing 1,2,3-triazole and diphenyl phosphate".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 186(2021):47-53. |
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| Synthesis and antiox（1443KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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