Synthesis and antioxidant activity of the inulin derivative bearing 1,2,3-triazole and diphenyl phosphate
Wei, Lijie1,2,3; Sui, Haishan1; Zhang, Jingjing2,3; Guo, Zhanyong2,3,4
Source PublicationINTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
ISSN0141-8130
2021-09-01
Volume186Pages:47-53
KeywordInulin derivative Antioxidant activity CuAAC Click chemistry
DOI10.1016/j.ijbiomac.2021.06.148
Corresponding AuthorGuo, Zhanyong(zhanyongguo@hotmail.com)
AbstractIn this paper, the inulin derivative (3) bearing 1,2,3-triazole and diphenyl phosphate was successfully synthesized by CuAAC Click chemistry. Detailed structural characterization was determined using FTIR spectroscopy, H-1 NMR spectroscopy, C-13 NMR spectroscopy, and elemental analysis. The antioxidant activities against hydroxyl radicals, superoxide radicals, and DPPH radicals were estimated in vitro respectively. The results showed that the antioxidant activity of the inulin derivative (3) was significantly enhanced compared with inulin. The inulin derivative (3) exhibited stronger radical scavenging abilities, especially against hydroxyl radicals and superoxide radicals. The scavenging values of the inulin derivative (3) were 98.2% and 95.4% at 1.6 mg/mL against hydroxyl radicals and superoxide radicals respectively. Besides, the scavenging value of the inulin derivative (3) increased by about 40% to scavenge DPPH radicals at 1.6 mg/mL than inulin. The results showed that the inulin derivative (3) bearing 1,2,3-triazole and diphenyl phosphate exhibited tremendously enhanced antioxidant activity compared with inulin. The synthetic strategy might provide an effective way to prepare novel inulin antioxidant biomaterials.
Funding OrganizationYouth Innovation Promotion Association CAS ; Natural Science Foundation of Shandong Province of China ; National Key Research and Development Pro-gram of China ; Natural Science Foundation of Shandong Province Science and Technology Development Plan
Indexed BySCI
Language英语
WOS KeywordREACTIVE OXYGEN ; CHITOSAN DERIVATIVES ; ANTIFUNGAL ACTIVITY ; SCAVENGING ACTIVITY ; CLICK CHEMISTRY ; PHOSPHORYLATION ; COPOLYMERS ; NITROGEN ; STRESS
WOS Research AreaBiochemistry & Molecular Biology ; Chemistry ; Polymer Science
WOS IDWOS:000688432800006
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Document Type期刊论文
Identifierhttp://ir.yic.ac.cn/handle/133337/29704
Collection海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心
海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室
Corresponding AuthorGuo, Zhanyong
Affiliation1.Weifang Adm Market Regulat, Weifang Inspect & Testing Ctr, Weifang 261000, Shandong, Peoples R China
2.Chinese Acad Sci, Key Lab Coastal Biol & Bioresource Utilizat, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
4.Chinese Acad Sci, Ctr Ocean Mega Sci, 7 Nanhai Rd, Qingdao 266071, Peoples R China
Recommended Citation
GB/T 7714
Wei, Lijie,Sui, Haishan,Zhang, Jingjing,et al. Synthesis and antioxidant activity of the inulin derivative bearing 1,2,3-triazole and diphenyl phosphate[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2021,186:47-53.
APA Wei, Lijie,Sui, Haishan,Zhang, Jingjing,&Guo, Zhanyong.(2021).Synthesis and antioxidant activity of the inulin derivative bearing 1,2,3-triazole and diphenyl phosphate.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,186,47-53.
MLA Wei, Lijie,et al."Synthesis and antioxidant activity of the inulin derivative bearing 1,2,3-triazole and diphenyl phosphate".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 186(2021):47-53.
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