| The extremely large chloroplast genome of the green alga Haematococcus pluvialis: Genome structure, and comparative analysis | |
Ren, Qingmin1,2; Wang, Yin-chu1,3 ; Lin, Yanni4; Zhen, Zhanghe1,2; Cui, Yulin1,3; Qin, Song1,3
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| Source Publication | ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS
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| ISSN | 2211-9264 |
| 2021-06-01 | |
| Volume | 56Pages:11 |
| Keyword | Haematococcus pluvialis Chloroplast genome Astaxanthin Non-coding regions Repeated sequences |
| DOI | 10.1016/j.algal.2021.102308 |
| Corresponding Author | Qin, Song(sqin@yic.ac.cn) |
| Abstract | Astaxanthin is arguably nature's most potent antioxidant, powerful to prevent free radical damage and oxidative stress. The microalga Haematococcus pluvialis seems to accumulate the highest levels of astaxanthin in nature and thus is currently the primary industrial source for natural astaxanthin production. The accumulation happens under photooxidative stress to quench radical damage from the photosynthesis, which is considered as one of the main reasons why chloroplast genomes are usually kept the small size and high guanine-cytosine (GC) content. We hypothesize that the outstanding astaxanthin production of the species may reflect its chloroplast genome features. In this study, the complete chloroplast genome of H. pluvialis FACHB-712 was sequenced and investigated. The genome is large, comprising 1.35 Mbp with 83 genes. However, the GC content is counterintuitively as high as 50.1%. The genome shows slight phylogenetic distance and genome structural differences in comparison with that of H. lacustris, whose species nomenclature is confusing and controversial. Moreover, a possible correlation between its powerful antioxidant capacity and the large chloroplast genome maintenance was further investigated. Strains of Chlorophyta and several strains with chloroplast genomes size of more than 500 kbp were used for comparative analysis. The evolutionary mechanism for the large chloroplast genome and and the contribution of non-coding region ratio and GC content to genome amplification is discussed.Large genomes may be associated with harsh habitats, and increased GC content may be used to increase stability. |
| Funding Organization | National Natural Science Foundation of China ; Major Basic Research Program of Shandong Province Natural Science Foundation ; Project of Innovation & Development of Marine Economy |
| Indexed By | SCI |
| Language | 英语 |
| WOS Keyword | NOV RHODELLOPHYCEAE ; PLASTID GENOMES ; CHLOROPHYCEAE ; SEQUENCE ; MITOCHONDRIAL ; ORGANELLE ; GENES ; ARCHITECTURE ; REPLICATION ; INSTABILITY |
| WOS Research Area | Biotechnology & Applied Microbiology |
| WOS ID | WOS:000663410100004 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.yic.ac.cn/handle/133337/29428 |
| Collection | 海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室 |
| Corresponding Author | Qin, Song |
| Affiliation | 1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Biol Resource Utilizat, Yantai 264003, Shandong, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao 266071, Peoples R China 4.Yantai Univ, Yantai 264005, Shandong, Peoples R China |
| Recommended Citation GB/T 7714 | Ren, Qingmin,Wang, Yin-chu,Lin, Yanni,et al. The extremely large chloroplast genome of the green alga Haematococcus pluvialis: Genome structure, and comparative analysis[J]. ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS,2021,56:11. |
| APA | Ren, Qingmin,Wang, Yin-chu,Lin, Yanni,Zhen, Zhanghe,Cui, Yulin,&Qin, Song.(2021).The extremely large chloroplast genome of the green alga Haematococcus pluvialis: Genome structure, and comparative analysis.ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS,56,11. |
| MLA | Ren, Qingmin,et al."The extremely large chloroplast genome of the green alga Haematococcus pluvialis: Genome structure, and comparative analysis".ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS 56(2021):11. |
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| The extremely large （2298KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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