一种降二萜类化合物及其制备和应用
Alternative TitleDrop diterpenoid type compound as well as preparation method and application thereof
Patent type发明
Patent Number2013106744468
季乃云; 苗凤萍
Rights Holder中国科学院烟台海岸带研究所
Application Date2013-12-11
2013-12-11
Status有效-授权
Country山东(37)
Abstract本发明涉及杀虫剂、抑菌剂和肿瘤细胞抑制剂领域,具体地说是一种海藻内生真菌来源的降二萜类化合物及其制备和应用。具体结构式如(I)所示,其制备方法为将温特曲霉(Aspergillus?wentii)NA3接种于真菌液体培养基中发酵培养,发酵产物纯化后,即为式(I)所示的降二萜类化合物。本发明获得的降二萜类化合物,经杀虫活性实验得出化合物半数致死浓度为1.81微克/毫升,同时该化合物还具有抑菌和抑制肿瘤细胞的活性。
Other AbstractThe invention relates to the field of insecticides, bacteriostats and tumor cell inhibitors, and in particular relates to a drop diterpenoid type compound from seaweed endophytes as well as a preparation method and application of the drop diterpenoid type compound. The drop diterpenoid type compound has a structural formula shown by a formula (I). The preparation method of the compound comprises the steps of inoculating Aspergillus wentii NA3 to a fungus liquid culture medium for fermentation culture, and purifying a fermentation product to obtain the drop diterpenoid type compound shown by the formula (I). An insecticidal activity test shows that the median lethal concentration of the drop diterpenoid type compound obtained by the preparation method disclosed by the invention is 1.81 micrograms per milliliter, and meanwhile, the compound has activities of inhibiting bacteria and tumor cells.
Subject AreaC07c49/747 ; A01n35/06 ; A01p7/04 ; A01p1/00 ; A61k31/122 ; A61p31/04 ; A61p35/00 ; C12p7/26 ; C12r1/71
URL查看原文
Application NumberCN201310674446.8
Open (Notice) NumberCN103613490A
Language中文
PCT Attributes
IPC Classification NumberC07C49/747 ; A01N35/06 ; A01P7/04 ; A01P1/00 ; A61K31/122 ; A61P31/04 ; A61P35/00 ; C12P7/26 ; C12R1/71
Patent Agent周秀梅 ; 李颖
Agency沈阳科苑专利商标代理有限公司 21002
CPC Classification NumberA01N35/06 ; C07C49/747 ; C07C2603/26 ; C12P7/26
Document Type专利
Identifierhttp://ir.yic.ac.cn/handle/133337/22268
Collection海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室
Affiliation中国科学院烟台海岸带研究所
Recommended Citation
GB/T 7714
季乃云,苗凤萍. 一种降二萜类化合物及其制备和应用. 2013106744468[P]. 2013-12-11.
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