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| Toxicity effects of di-(2-ethylhexyl) phthalate to Eisenia fetida at enzyme, cellular and genetic levels | |
Ma, Tingting1,2; Zhou, Wei3; Chen, Li'ke2,4; Wu, Longhua2; Christie, Peter2; Zhang, Haibo2,5 ; Luo, Yongming2,5; Luo, YM (reprint author), Chinese Acad Sci, Inst Soil Sci, Key Lab Soil Environm & Pollut Remediat, Nanjing, Jiangsu, Peoples R China.
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| 发表期刊 | PLOS ONE
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| ISSN | 1932-6203 |
| 2017-03-20 | |
| 卷号 | 12期号:3页码:e0173957 |
| 关键词 | Exposure Biomarker Foetida Stress Soil Metallothionein Ecotoxicity Earthworms Activation Apoptosis |
| DOI | 10.1371/journal.pone.0173957 |
| 产权排序 | [Ma, Tingting] Hubei Univ Arts & Sci, Inst Hanjiang, Xiangyang, Peoples R China; [Ma, Tingting; Chen, Li'ke; Wu, Longhua; Christie, Peter; Zhang, Haibo; Luo, Yongming] Chinese Acad Sci, Inst Soil Sci, Key Lab Soil Environm & Pollut Remediat, Nanjing, Jiangsu, Peoples R China; [Zhou, Wei] Hubei Univ Arts & Sci, Sch Civil Engn & Architecture, Xiangyang, Peoples R China; [Chen, Li'ke] Shanghai Res Inst Chem Ind, Shanghai, Peoples R China; [Zhang, Haibo; Luo, Yongming] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai, Peoples R China |
| 作者部门 | 中科院海岸带环境过程与生态修复重点实验室 |
| 英文摘要 | Di-(2-ethylhexyl) phthalate (DEHP) is a dominant phthalic acid ester (PAE) that has aroused public concern due to its resistance to degradation and its toxicity as an endocrine- disrupting compound. Effects of different concentrations of DEHP on Eisenia fetida in spiked natural soil have been studied in the body of the earthworm by means of soil cultivation tests 7, 14, 21 and 28 days after exposure. The results indicated that, in general, superoxide dismutase (SOD) activity, malondialdehyde (MDA) content, metallothionein (MT) content, the expression of heat shock protein 70 (HSP 70) and all the tested geno-toxicity parameters are promoted as time elapses and with increasing concentration of DEHP. However, peroxidase (POD) activity, neutral red retention time (NRRT) and mitochondrial membrane potential difference values were found to decrease even at a low concentration of DEHP of 1 mg kg -1 soil (p< 0.05). Clear toxic effects of DEHP on E. fetida have been generally recognized by means of the disturbance of antioxidant enzyme activity/ content and critical proteins, cell membrane and organelle disorder and DNA damage estimated by length of tail, tail DNA ratio, and tail moment parameters. A concentration of DEHP of 3 mg kg-1 may be recommended as a precaution against the potential risk of PAEs in soils and for indicating suitable threshold values for other soil animals and soil micro-organisms. |
| 文章类型 | Article |
| 资助机构 | National Natural Science Foundation of China(41401581 TM ; 41271326 B LW) |
| 收录类别 | SCI |
| 语种 | 英语 |
| 关键词[WOS] | EXPOSURE ; BIOMARKER ; FOETIDA ; STRESS ; SOIL ; METALLOTHIONEIN ; ECOTOXICITY ; EARTHWORMS ; ACTIVATION ; APOPTOSIS |
| 研究领域[WOS] | Science & Technology - Other Topics |
| WOS记录号 | WOS:000398945800037 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.yic.ac.cn/handle/133337/22063 |
| 专题 | 中国科学院海岸带环境过程与生态修复重点实验室 中国科学院海岸带环境过程与生态修复重点实验室_污染过程与控制实验室 |
| 通讯作者 | Luo, YM (reprint author), Chinese Acad Sci, Inst Soil Sci, Key Lab Soil Environm & Pollut Remediat, Nanjing, Jiangsu, Peoples R China. |
| 作者单位 | 1.Hubei Univ Arts & Sci, Inst Hanjiang, Xiangyang, Peoples R China 2.Chinese Acad Sci, Inst Soil Sci, Key Lab Soil Environm & Pollut Remediat, Nanjing, Jiangsu, Peoples R China 3.Hubei Univ Arts & Sci, Sch Civil Engn & Architecture, Xiangyang, Peoples R China 4.Shanghai Res Inst Chem Ind, Shanghai, Peoples R China 5.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ma, Tingting,Zhou, Wei,Chen, Li'ke,et al. Toxicity effects of di-(2-ethylhexyl) phthalate to Eisenia fetida at enzyme, cellular and genetic levels[J]. PLOS ONE,2017,12(3):e0173957. |
| APA | Ma, Tingting.,Zhou, Wei.,Chen, Li'ke.,Wu, Longhua.,Christie, Peter.,...&Luo, YM .(2017).Toxicity effects of di-(2-ethylhexyl) phthalate to Eisenia fetida at enzyme, cellular and genetic levels.PLOS ONE,12(3),e0173957. |
| MLA | Ma, Tingting,et al."Toxicity effects of di-(2-ethylhexyl) phthalate to Eisenia fetida at enzyme, cellular and genetic levels".PLOS ONE 12.3(2017):e0173957. |
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