The invention relates to the field of insecticides, particularly application of a natural seaweed endophytic fungus diterpene alkaloid compound. The seaweed endophytic fungus diterpene alkaloid compound has a disinsection function, and is disclosed as Formula (I). In the invention, the fungus Aspergillus oryzae cf-2 which is separated from ocean red algae Heterosiphonia is fermentated, extracted and separated to obtain the diterpene alkaloid natural compound. The insecticidal activity experiment indicates that the lethality rate of the 100 mcg/ml diterpene alkaloid compound for Artemia is 60.3%.
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