| Genome-wide analysis of the hard clam mitogen-activated protein kinase kinase gene family and their transcriptional profiles under abiotic stress | |
| Hu, Zhi1,2,3,4,5,6; Song, Hao1,2,3,4,6; Feng, Jie1,2,3,4,6; Zhou, Cong1,2,3,4,5,6; Yang, Mei-Jie1,2,3,4,6; Shi, Pu1,2,3,4,5,6; Yu, Zheng-Lin7; Li, Yong-Ren8; Guo, Yong-Jun8; Li, Hai-Zhou9; Wang, Su-Yao10; Xue, Jiang-Han11; Zhang, Tao1,2,3,4,6 | |
| Source Publication | MARINE ENVIRONMENTAL RESEARCH
 |
| ISSN | 0141-1136 |
| 2022-04-01 | |
| Volume | 176Pages:10 |
| Keyword | Mercenaria mercenaria MAPKK gene family Transcriptional profiles Abiotic stress |
| DOI | 10.1016/j.marenvres.2022.105606 |
| Abstract | Mitogen-activated protein kinase kinase (MAPKK) was the hub component of the Mitogen-activated protein kinase (MAPK) signaling pathway and played an important role in the cellular response to environmental stress. In this study, we identified five MmMAPKK genes in hard clam Mercenaria mercenaria and found that all MmMAPKK genes contain a conserved protein kinase domain. The MmMAPKK genes derived from dispersed duplication were unevenly distributed in three chromosomes. Although the genome size was highly variable among different bivalve mollusks, the number of MAPKK genes was relatively stable. Phylogenetic analysis showed that bivalve MAPKK was divided into five clades, and amino acid sequences of MAPKK from the same clade consisted of similar conserved motifs. The syntenic analysis demonstrated that MmMAPKKs had the highest number of homologous gene pairs with Cyclina sinensis. MmMAPKKs were ubiquitously expressed in all examined tissues, and all MmMAPKK genes were highly expressed in the ovary. MmMAPKK genes showed stress-specific expression under envirionmental stress. MmMAPKK7 showed an upregulated in heat and heat plus hypoxia stress while MmMAPKK1 showed an upregulated in hypoxic stress groups. Dynamic changes of MmMAPKK7, MmMAPKK6 and MmMAPKK1 in hemocytes were observed in response to air exposure. MmMAPKK4 significantly downregulated after air exposure for five days. MmMAPKK7 and MmMAPKK6 might participate in adaptation to low salinity stress. Our results provided useful information about MAPKK and laid a foundation for further studies on MAPKK evolution in the bivalve. |
| Indexed By | SCI |
| Language | 英语 |
| WOS Keyword | SIGNAL-TRANSDUCTION PATHWAYS ; SCALLOP PATINOPECTEN-YESSOENSIS ; MAP KINASE ; MYTILUS-GALLOPROVINCIALIS ; RESPONSES ; IDENTIFICATION ; EVOLUTION ; EXPOSURE ; JNK |
| WOS Research Area | Environmental Sciences & Ecology ; Marine & Freshwater Biology ; Toxicology |
| WOS ID | WOS:000795140000006 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.yic.ac.cn/handle/133337/31087 |
| Collection | 中科院烟台海岸带研究所知识产出 |
| Corresponding Author | Zhang, Tao |
| Affiliation | 1.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Marine Ecol & Environm Sci, Qingdao 266071, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Ecol & Environm Sci, Qingdao 266237, Peoples R China 3.Chinese Acad Sci, Ctr Ocean Megasci, Qingdao 266071, Peoples R China 4.Chinese Acad Sci, Inst Oceanol, CAS Engn Lab Marine Ranching, Qingdao 266071, Peoples R China 5.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 6.Shandong Prov Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 7.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China 8.Tianjin Agr Univ, Fisheries Coll, Tianjin Key Lab Aqua Ecol & Aquaculture, Tianjin 300384, Peoples R China 9.Shandong Fu Han Ocean Sci Tech Co Ltd, Haiyang 265100, Peoples R China 10.Qingdao 58 High Sch Shandong Prov, Qingdao 262000, Peoples R China 11.Chinese Univ Hong Kong, Shenzhen 518172, Peoples R China |
| Recommended Citation GB/T 7714 | Hu, Zhi,Song, Hao,Feng, Jie,et al. Genome-wide analysis of the hard clam mitogen-activated protein kinase kinase gene family and their transcriptional profiles under abiotic stress[J]. MARINE ENVIRONMENTAL RESEARCH,2022,176:10. |
| APA | Hu, Zhi.,Song, Hao.,Feng, Jie.,Zhou, Cong.,Yang, Mei-Jie.,...&Zhang, Tao.(2022).Genome-wide analysis of the hard clam mitogen-activated protein kinase kinase gene family and their transcriptional profiles under abiotic stress.MARINE ENVIRONMENTAL RESEARCH,176,10. |
| MLA | Hu, Zhi,et al."Genome-wide analysis of the hard clam mitogen-activated protein kinase kinase gene family and their transcriptional profiles under abiotic stress".MARINE ENVIRONMENTAL RESEARCH 176(2022):10. |
| Files in This Item: | There are no files associated with this item. | |||||
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.
Edit Comment