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Anti-inflammatory and immunomodulatory activities of polysaccharide from Chlorella stigmatophora and Phaeodactylum tricornutum
S. Guzmán, A. Gato, M. Lamela, M. Freire-Garabal, J. M. Calleja
发表期刊Phytotherapy Research
ISSN0951-418X
2003
卷号17期号:6页码:665-670
通讯作者A. Gato
英文摘要Crude polysaccharide extracts were obtained from aqueous extracts of the microalgae Chlorella stigmatophora and Phaeodactylum tricornutum. The crude extracts were fractionated by ion-exchange chromatography on DEAE-cellulose columns. The molecular weights of the polysaccharides in each fraction were estimated by gel filtration on Sephacryl columns. The crude polysaccharide extracts of both microalgae showed anti-inflammatory activity in the carrageenan-induced paw edema test. In assays of effects on the delayed hyper-sensitivity response, and on phagocytic activity assayed in vivo and in vitro, the C. stigmatophora extract showed immunosuppressant effects, while the P. tricornutum extract showed immunostimulatory effects. Copyright © 2003 John Wiley & Sons, Ltd.
语种英语
文献类型期刊论文
条目标识符http://ir.yic.ac.cn/handle/133337/2935
专题科研共享资源
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S. Guzmán, A. Gato, M. Lamela, M. Freire-Garabal, J. M. Calleja. Anti-inflammatory and immunomodulatory activities of polysaccharide from Chlorella stigmatophora and Phaeodactylum tricornutum[J]. Phytotherapy Research,2003,17(6):665-670.
APA S. Guzmán, A. Gato, M. Lamela, M. Freire-Garabal, J. M. Calleja.(2003).Anti-inflammatory and immunomodulatory activities of polysaccharide from Chlorella stigmatophora and Phaeodactylum tricornutum.Phytotherapy Research,17(6),665-670.
MLA S. Guzmán, A. Gato, M. Lamela, M. Freire-Garabal, J. M. Calleja."Anti-inflammatory and immunomodulatory activities of polysaccharide from Chlorella stigmatophora and Phaeodactylum tricornutum".Phytotherapy Research 17.6(2003):665-670.
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