支撑部门知识库

QQ客服 官方微博 反馈留言

	Antimicrobial Sesquiterpenoid Derivatives and Monoterpenoids from the Deep-Sea Sediment-Derived Fungus Aspergillus versicolor SD-330
	Li, XD; Li, XM; Yin, XL; Li, X; Wang, BG
发表期刊	MARINE DRUGS
	2019-10
卷号	17期号:10页码:563
关键词	deep-sea sediment-derived fungus Aspergillus versicolor bisabolane-type sesquiterpenoids monoterpenoids antimicrobial activity
研究领域	Chemistry, Medicinal
DOI	10.3390/md17100563
产权排序	[Li, Xiao-Dong; Li, Xiao-Ming; Li, Xin; Wang, Bin-Gui] Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Nanhai Rd 7, Qingdao 266071, Shandong, Peoples R China; [Li, Xiao-Dong; Yin, Xiu-Li] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Chunhui Rd 17, Yantai 264003, Peoples R China; [Li, Xiao-Ming; Li, Xin; Wang, Bin-Gui] Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Wenhai Rd 1, Qingdao 266237, Shandong, Peoples R China; [Li, Xiao-Ming; Li, Xin; Wang, Bin-Gui] Chinese Acad Sci, Ctr Ocean Mega Sci, Nanhai Rd 7, Qingdao 266071, Shandong, Peoples R China
通讯作者	Li, Xin(lixin@qdio.ac.cn) ; Wang, Bin-Gui(wangbg@ms.qdio.ac.cn)
作者部门	支撑部门
英文摘要	Two new antimicrobial bisabolane-type sesquiterpenoid derivatives, ent-aspergoterpenin C (compound 1) and 7-O-methylhydroxysydonic acid (2), and two new butyrolactone-type monoterpenoids, pestalotiolactones C (3) and D (4), along with a known monoterpenoid pestalotiolactone A (5) and four known bisabolane sesquiterpenoids (6-9), were isolated and identified from the deep-sea sediment-derived fungus Aspergillus versicolor SD-330. The structures of these compounds were elucidated on the basis of spectroscopic analysis, and the absolute configurations of the new compounds 1-4 were determined by the combination of NOESY and TDDFT-ECD calculations and X-ray crystallographic analysis. Additionally, we first determined and reported the absolute configuration of the known monoterpenoid pestalotiolactone A (5) through the X-ray crystallographic experiment. All of these isolated compounds were evaluated for antimicrobial activities against human and aquatic pathogenic bacteria. Compounds 1, 2, 6 and 9 exhibited selective inhibitory activities against zoonotic pathogenic bacteria such as Escherichia coli, Edwardsiella tarda, Vibrio anguillarum and V. harveyi, with MIC values ranging from 1.0 to 8.0 mu g/mL.
文章类型	Article
资助机构	Strategic Priority Research Program of the Chinese Academy of SciencesChinese Academy of Sciences [XDA22050401] ; Aoshan Scientific and Technological Innovation Project of Qingdao National Laboratory for Marine Science and Technology [2016ASKJ14] ; National Natural Science Foundation of ChinaNational Natural Science Foundation of China [31700043] ; China Postdoctoral Science FoundationChina Postdoctoral Science Foundation [2016LH00033, 2017M612358, 2017M612360] ; Research Vessel KEXUE of the National Major Science and Technology Infrastructure from the Chinese Academy of Sciences [KEXUE2018G28] ; Taishan Scholar Project from Shandong Province ; Shandong Provincial Natural Science FoundationNatural Science Foundation of Shandong Province [ZR2017BB073]
收录类别	SCI
语种	英语
关键词[WOS]	BISABOLANE SESQUITERPENES ; SECONDARY METABOLITES ; ENDOPHYTIC FUNGUS ; SYDONIC ACID ; A-D ; ALKALOIDS
研究领域[WOS]	Chemistry, Medicinal
WOS记录号	WOS:000498064500023
引用统计	被引频次：26[WOS]   [WOS记录]     [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.yic.ac.cn/handle/133337/24841
专题	支撑部门
作者单位	1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Nanhai Rd 7, Qingdao 266071, Shandong, Peoples R China; 2.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Chunhui Rd 17, Yantai 264003, Peoples R China; 3.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Wenhai Rd 1, Qingdao 266237, Shandong, Peoples R China; 4.Chinese Acad Sci, Ctr Ocean Mega Sci, Nanhai Rd 7, Qingdao 266071, Shandong, Peoples R China
推荐引用方式 GB/T 7714	Li, XD,Li, XM,Yin, XL,et al. Antimicrobial Sesquiterpenoid Derivatives and Monoterpenoids from the Deep-Sea Sediment-Derived Fungus Aspergillus versicolor SD-330[J]. MARINE DRUGS,2019,17(10):563.
APA	Li, XD,Li, XM,Yin, XL,Li, X,&Wang, BG.(2019).Antimicrobial Sesquiterpenoid Derivatives and Monoterpenoids from the Deep-Sea Sediment-Derived Fungus Aspergillus versicolor SD-330.MARINE DRUGS,17(10),563.
MLA	Li, XD,et al."Antimicrobial Sesquiterpenoid Derivatives and Monoterpenoids from the Deep-Sea Sediment-Derived Fungus Aspergillus versicolor SD-330".MARINE DRUGS 17.10(2019):563.

条目包含的文件
文件名称/大小	文献类型	版本类型	开放类型	使用许可
Antimicrobial Sesqui（2055KB）	期刊论文	出版稿	开放获取	CC BY-NC-SA	浏览 请求全文

个性服务

推荐该条目

保存到收藏夹

查看访问统计

导出为Endnote文件

谷歌学术

谷歌学术中相似的文章

[Li, XD]的文章

[Li, XM]的文章

[Yin, XL]的文章

百度学术

百度学术中相似的文章

[Li, XD]的文章

[Li, XM]的文章

[Yin, XL]的文章

必应学术

必应学术中相似的文章

[Li, XD]的文章

[Li, XM]的文章

[Yin, XL]的文章

相关权益政策

暂无数据

收藏/分享

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。