A fatty acid derivative acts as a sea lamprey migratory pheromone | |
其他题名 | Hoye, Thomas R.; Li, Weiming |
Li K(李可)1; Brant, Cory O.1; Huertas, Mar1,5; Hessler, Edward J.2; Mezei, Gellert3; Scott, Anne M.1; Hoye, Thomas R.4; Li, Weiming1 | |
发表期刊 | Proceedings of the National Academy of Sciences of United States of America |
ISSN | 0027-8424 |
2018 | |
卷号 | 115期号:34页码:8603-8608 |
关键词 | Chemical Ecology Anadromous Migration Olfaction Animal Behavior Agnatha |
DOI | 10.1073/pnas.1803169115 |
作者部门 | Fisheries and Wildlife |
英文摘要 | Olfactory cues provide critical information for spatial orientation of fish, especially in the context of anadromous migrations. Born in freshwater, juveniles of anadromous fish descend to the ocean where they grow into adults before migrating back into freshwater to spawn. The reproductive migrants, therefore, are under selective pressures to locate streams optimal for offspring survival. Many anadromous fish use olfactory cues to orient toward suitable streams. However, no behaviorally active compounds have been identified as migratory cues. Extensive studies have shown that the migratory adult sea lampreys (Petromyzon marinus), a jawless fish, track a pheromone emitted by their stream-dwelling larvae, and, consequently, enter streams with abundant larvae. We fractionated extracts of larval sea lamprey washings with guidance from a bioassay that measures in-stream migratory behaviors of adults and identified four dihydroxylated tetrahydrofuran fatty acids, of which (+)-(2S, 3S, 5R)-tetrahydro-3-hydroxy-5-[(1R)-1-hydroxyhexyl]-2-furanoctanoic acid was shown as a migratory pheromone. The chemical structure was elucidated by spectroscopies and confirmed by chemical synthesis and X-ray crystallography. The four fatty acids were isomer-specific and enantiomer-specific in their olfactory and behavioral activities. A synthetic copy of the identified pheromone was a potent stimulant of the adult olfactory epithelium, and, at 5 x 10(-13) M, replicated the extracts of larval washings in biasing adults into a tributary stream. Our results reveal a pheromone that bridges two distinct life stages and guides orientation over a large space that spans two different habitats. The identified molecule may be useful for control of the sea lamprey. |
文章类型 | Article |
收录类别 | SCI |
语种 | 英语 |
关键词[WOS] | Laurentian Great-lakes ; Petromyzon-marinus L. ; Unique Bile-acids ; Anadromous Fishes ; Odor ; Identification ; Water ; Tetrahydrofurandiols ; Lepidoptera ; Management |
研究领域[WOS] | Multidisciplinary Sciences |
WOS记录号 | WOS:000442351000055 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.yic.ac.cn/handle/133337/24107 |
专题 | 个人在本单位外知识产出 |
通讯作者 | Hoye, Thomas R.; Li, Weiming |
作者单位 | 1.Michigan State University 2.Bridge Organ Co 3.Western Michigan Univ 4.Univ Minnesota, Dept Chem 5.Texas State Univ |
推荐引用方式 GB/T 7714 | Li K,Brant, Cory O.,Huertas, Mar,et al. A fatty acid derivative acts as a sea lamprey migratory pheromone[J]. Proceedings of the National Academy of Sciences of United States of America,2018,115(34):8603-8608. |
APA | Li K.,Brant, Cory O..,Huertas, Mar.,Hessler, Edward J..,Mezei, Gellert.,...&Li, Weiming.(2018).A fatty acid derivative acts as a sea lamprey migratory pheromone.Proceedings of the National Academy of Sciences of United States of America,115(34),8603-8608. |
MLA | Li K,et al."A fatty acid derivative acts as a sea lamprey migratory pheromone".Proceedings of the National Academy of Sciences of United States of America 115.34(2018):8603-8608. |
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文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
A fatty acid derivat(2188KB) | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | 浏览 请求全文 |
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