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Abnormality of mussel in the early developmental stages induced by graphene and triphenyl phosphate: In silico toxicogenomic data-mining, in vivo, and toxicity pathway-oriented approach 期刊论文
AQUATIC TOXICOLOGY, 2023, 卷号: 263, 页码: 11
作者:  Wang, Xiaoqing;  Li, Fei;  Meng, Xiangjing;  Xia, Chunlei;  Ji, Chenglong;  Wu, Huifeng
收藏  |  浏览/下载：91/0  |  提交时间：2023/11/15
Plastic additives  Graphene-based nanomaterials  Toxicogenomic data mining  Combined hazards  Developmental abnormality  
Characterization of oxidative damage induced by nanoparticles via mechanism-driven machine learning approaches 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2023, 卷号: 871, 页码: 11
作者:  Wang, Xiaoqing;  Li, Fei;  Teng, Yuefa;  Ji, Chenglong;  Wu, Huifeng
收藏  |  浏览/下载：29/0  |  提交时间：2024/01/26
Toxic effects  Machine learning  Risk assessment  Mechanism -driven analysis  TiO2-based engineered nanoparticles(nTiO2)  
Potential adverse outcome pathways with hazard identification of organophosphate esters 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2022, 卷号: 851, 页码: 13
作者:  Wang, Xiaoqing;  Li, Fei;  Teng, Yuefa;  Ji, Chenglong;  Wu, Huifeng
收藏  |  浏览/下载：196/0  |  提交时间：2023/01/11
Organophosphate esters (OPEs)  Network-centric analysis  Risk assessment  Adverse outcome pathway  Quantitative weight of evidence  
Graphene-triphenyl phosphate (TPP) co-exposure in the marine environment: Interference with metabolism and immune regulation in mussel Mytilus galloprovincialis 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2021, 卷号: 227, 页码: 8
作者:  Li, Fei;  Meng, Xiangjing;  Wang, Xiaoqing;  Ji, Chenglong;  Wu, Huifeng
收藏  |  浏览/下载：217/0  |  提交时间：2022/06/16
Nanomaterials  Graphene  Organophosphorus ester (OPEs)  Mytilus  Joint effects  Multi-omics  
Tetrabromobisphenol A induced reproductive endocrine-disrupting effects in mussel Mytilus galloprovincialis 期刊论文
JOURNAL OF HAZARDOUS MATERIALS, 2021, 卷号: 416, 页码: 9
作者:  Wang, Shuang;  Ji, Chenglong;  Li, Fei;  Zhan, Junfei;  Sun, Tao;  Tang, Jianhui;  Wu, Huifeng
浏览  |  Adobe PDF(4030Kb)  |  收藏  |  浏览/下载：522/212  |  提交时间：2021/10/21
Brominated flame retardants  Marine invertebrates  Endocrine disruptor  Steroids sulfonation  
Integration of Computational Toxicology, Toxicogenomics Data Mining, and Omics Techniques to Unveil Toxicity Pathways 期刊论文
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2021, 卷号: 9, 期号: 11, 页码: 4130-4138
作者:  Wang, Xiaoqing;  Li, Fei;  Chen, Jingwen;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(3938Kb)  |  收藏  |  浏览/下载：699/289  |  提交时间：2021/05/22
Adverse outcome pathway (AOP)  Comparative toxicogenomics database (CTD)  Triphenyl phosphate (TPP)  Molecular dynamics (MD)  Transcriptome analyses  
Proteomic analysis revealed gender-specific responses of mussels (Mytilus galloprovincialis) to trichloropropyl phosphate (TCPP) exposure 期刊论文
ENVIRONMENTAL POLLUTION, 2020, 卷号: 267, 页码: 11
作者:  Zhong, Mingyu;  Wu, Huifeng;  Li, Fei;  Shan, Xiujuan;  Ji, Chenglong
浏览  |  Adobe PDF(3290Kb)  |  收藏  |  浏览/下载：509/186  |  提交时间：2021/06/07
Trichloropropyl phosphate (TCPP)  Mytilus galloprovincialis  Gender-specific effects  iTRAQ  Proteomics  
Transcriptomic, proteomic and metabolomic profiling unravel the mechanisms of hepatotoxicity pathway induced by triphenyl phosphate (TPP) 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 205, 页码: 9
作者:  Wang, Xiaoqing;  Li, Fei;  Liu, Jialin;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(6774Kb)  |  收藏  |  浏览/下载：375/53  |  提交时间：2021/06/21
Triphenyl phosphate (TPP)  Multi-omit approach  Hepatotoxicity  
A defensin-like antimicrobial peptide from the manila clam Ruditapes philippinarum: Investigation of the antibacterial activities and mode of action 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2018, 卷号: 80, 页码: 274-280
作者:  Yang, Dinglong;  Zhang, Qianqian;  Wang, Qing;  Chen, Lizhu;  Liu, Yongliang;  Cong, Ming;  Wu, Huifeng;  Li, Fei;  Ji, Chenglong;  Zhao, Jianmin
收藏  |  浏览/下载：577/0  |  提交时间：2018/09/18
Ruditapes philippinarum  Defensin  Antimicrobial activity  Membrane disruption