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Abnormality of mussel in the early developmental stages induced by graphene and triphenyl phosphate: In silico toxicogenomic data-mining, in vivo, and toxicity pathway-oriented approach 期刊论文
AQUATIC TOXICOLOGY, 2023, 卷号: 263, 页码: 11
作者:  Wang, Xiaoqing;  Li, Fei;  Meng, Xiangjing;  Xia, Chunlei;  Ji, Chenglong;  Wu, Huifeng
收藏  |  浏览/下载：91/0  |  提交时间：2023/11/15
Plastic additives  Graphene-based nanomaterials  Toxicogenomic data mining  Combined hazards  Developmental abnormality  
基于有害结局路径网络的有机磷酸酯毒性筛查及机制研究 学位论文
工学博士: 中国科学院烟台海岸带研究所, 2023
作者:  王晓晴
Adobe PDF(21053Kb)  |  收藏  |  浏览/下载：239/4  |  提交时间：2023/06/28
新污染物  有机磷酸酯  有害结局路径网络  计算毒理学  风险预测与评估  
Characterization of oxidative damage induced by nanoparticles via mechanism-driven machine learning approaches 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2023, 卷号: 871, 页码: 11
作者:  Wang, Xiaoqing;  Li, Fei;  Teng, Yuefa;  Ji, Chenglong;  Wu, Huifeng
收藏  |  浏览/下载：30/0  |  提交时间：2024/01/26
Toxic effects  Machine learning  Risk assessment  Mechanism -driven analysis  TiO2-based engineered nanoparticles(nTiO2)  
Effects of an Episodic Storm-Induced Flooding Event on the Biogeochemistry of a Shallow, Highly Turbid, Semi-Enclosed Embayment (Laizhou Bay, Bohai Sea) 期刊论文
SUSTAINABILITY, 2023, 卷号: 15, 期号: 1, 页码: 12
作者:  Meng, Ling;  Xing, Qianguo;  Gao, Xuelu;  Ji, Diansheng;  Qu, Fanzhu;  Wang, Xiaoqing;  Ji, Ling
收藏  |  浏览/下载：91/0  |  提交时间：2023/08/17
episodic flood  freshwater inflows  biogeochemical indicators  chlorophyll a  Laizhou Bay  
基于极限梯度提升算法和特征筛选方法的羊角月牙藻(Selenastrum capricornutum)急性毒性定量构效关系(QSAR)模型的建立与应用 期刊论文
生态毒理学报, 2023, 卷号: 18, 期号: 3, 页码: 33-46
作者:  滕跃发;  王晓晴;  李斐;  吉成龙;  吴惠丰
收藏  |  浏览/下载：37/0  |  提交时间：2024/01/26
多环芳烃  羊角月牙藻  定量构效关系  机器学习  极限梯度提升  特征筛选  
Graphene Materials Induce Chronic Aquatic Toxicity Through the Regulation of DNA Damage, Metabolism and Oxidative Stress in Daphnia Magna 期刊论文
SSRN, 2023
作者:  Huang, Yang;  Yao, Hongye;  Li, Xuehua;  Li, Fei;  Wang, Xiaoqing;  Fu, Zhiqiang;  Li, Ningjing;  Chen, Jingwen
收藏  |  浏览/下载：38/0  |  提交时间：2024/01/26
Detoxification  Metabolism  Nanostructured materials  Proteins  Toxicity  Transcription  
Potential adverse outcome pathways with hazard identification of organophosphate esters 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2022, 卷号: 851, 页码: 13
作者:  Wang, Xiaoqing;  Li, Fei;  Teng, Yuefa;  Ji, Chenglong;  Wu, Huifeng
收藏  |  浏览/下载：199/0  |  提交时间：2023/01/11
Organophosphate esters (OPEs)  Network-centric analysis  Risk assessment  Adverse outcome pathway  Quantitative weight of evidence  
Critical features identification for chemical chronic toxicity based on mechanistic forecast models 期刊论文
ENVIRONMENTAL POLLUTION, 2022, 卷号: 307, 页码: 8
作者:  Wang, Xiaoqing;  Li, Fei;  Chen, Jingwen;  Teng, Yuefa;  Ji, Chenglong;  Wu, Huifeng
收藏  |  浏览/下载：247/0  |  提交时间：2022/07/26
Computational toxicology  Machine learning  Structural alerts  Risk assessment  Prioritization rank  
Critical target identification and human health risk ranking of metal ions based on mechanism-driven modeling 期刊论文
CHEMOSPHERE, 2022, 卷号: 301, 页码: 9
作者:  Wang, Xiaoqing;  Teng, Yuefa;  Ji, Chenglong;  Wu, Huifeng;  Li, Fei
收藏  |  浏览/下载：245/0  |  提交时间：2022/07/26
Metal ions  p53  QSAR  Genetic toxicity  Human health risk  
Toxicity pathways of lipid metabolic disorders induced by typical replacement flame retardants via data-driven analysis, in silico and in vitro approaches 期刊论文
CHEMOSPHERE, 2022, 卷号: 287, 页码: 9
作者:  Wang, Xiaoqing;  Wang, Li;  Li, Fei;  Teng, Yuefa;  Ji, Chenglong;  Wu, Huifeng
收藏  |  浏览/下载：225/0  |  提交时间：2022/06/16
Toxicity pathways  Lipid metabolism disorder  Bibliometric analysis  Computational toxicology  Data-driven analysis