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升温与聚苯乙烯微塑料复合暴露对长牡蛎血细胞功能、免疫基因表达和能量代谢的影响 期刊论文
渔业科学进展, 2023, 卷号: 45, 期号: 01, 页码: 161-171
作者:  杜蕴超;  任晶莹;  滕佳;  赵建民;  张天宇;  王清
收藏  |  浏览/下载:48/0  |  提交时间:2024/01/26
长牡蛎  微塑料  升温  免疫  能量代谢  
14-3-3 zeta and 14-3-3 epsilon are involved in innate immune responses in Pacific abalone (Haliotis discus hannai) 期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2021, 卷号: 124, 页码: 12
作者:  Xue, Rui;  Yang, Dinglong;  Han, Yijing;  Deng, Qinyou;  Wang, Xin;  Liu, Xiangquan;  Zhao, Jianmin
Adobe PDF(10647Kb)  |  收藏  |  浏览/下载:427/62  |  提交时间:2021/11/09
14-3-3 zeta  14-3-3 epsilon  Immune responses  Pacific abalone  
Seawater acidification aggravated cadmium toxicity in the oyster Crassostrea gigas: Metal bioaccumulation, subcellular distribution and multiple physiological responses 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2018, 卷号: 642, 页码: 809-823
作者:  Cao, Ruiwen;  Liu, Yongliang;  Wang, Qing;  Dong, Zhijun;  Yang, Dinglong;  Liu, Hui;  Ran, Wen;  Qu, Yi;  Zhao, Jianmin
Adobe PDF(3991Kb)  |  收藏  |  浏览/下载:413/115  |  提交时间:2020/07/08
Ocean acidification  Cadmium  Crassostrea gigas  Physiological response  Apoptosis  Bioconcentration  
Two macrophage migration inhibitory factors (MIFs) from the clam Ruditapes philippinarum: Molecular characterization, localization and enzymatic activities 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2018, 卷号: 78, 页码: 158-168
作者:  Wang, Dan;  Yang, Dinglong;  Wang, Qing;  Zhao, Ye;  Li, Chenghua;  Wei, Qianyu;  Han, Yijing;  Zhao, Jianmin
Adobe PDF(2259Kb)  |  收藏  |  浏览/下载:248/44  |  提交时间:2020/07/08
Manila clam  Macrophage migration inhibitory factor  Immune response  Enzymatic activity  
石墨烯与抑癌基因p53 DNA片段相互作用的分子模拟与光谱学验证 期刊论文
生态毒理学报, 2017, 卷号: 12, 期号: 3, 页码: 243-250
作者:  吴惠丰;  张明兴;  李斐;  曹天贵;  李雪花;  赵建民
收藏  |  浏览/下载:158/0  |  提交时间:2020/07/07
p53-DNA  graphene(G)  p53-DNA  binding interaction  molecular dynamics simulations  spectroscopic methods  石墨烯  相互作用  分子动力学模拟  光谱法  
一种预测生物标志物p53与有机磷酸酯阻燃剂相互作用亲和力的方法 专利
专利号: 2014101576210, 申请日期: 2017-01-11,
发明人:  李斐;  曹璐璐;  吴惠丰;  赵建民
收藏  |  浏览/下载:5/0  |  提交时间:2024/01/26
典型持久性有机污染物与抑癌基因相互作用的分子模拟与验证 期刊论文
科学通报, 2015, 卷号: 60, 期号: 19, 页码: 1804-1809
作者:  吴惠丰;  曹璐璐;  李斐;  李雪花;  赵建民
浏览  |  Adobe PDF(1577Kb)  |  收藏  |  浏览/下载:693/312  |  提交时间:2016/12/15
持久性有机污染物  P53  2  分子模拟  2'  光谱法  4  4'-四溴联苯醚(Bde-47)  
BDE-47对人胚肾细胞HEK293的毒理效应及作用机制 期刊论文
生态毒理学报, 2015, 卷号: ., 期号: 2, 页码: 236-242
作者:  曹璐璐;  李斐;  吴惠丰;  赵建民
浏览  |  Adobe PDF(304Kb)  |  收藏  |  浏览/下载:383/160  |  提交时间:2021/06/16
2,2’,4,4’-四溴联苯醚(BDE-47)  人胚肾细胞  细胞凋亡  氧化损伤  p53  Bax  
Determination and Prediction of the Binding Interaction between Organophosphate Flame Retardants and p53 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2014, 卷号: 27, 期号: 11, 页码: 1918-1925
作者:  Li, Fei;  Yang, Xianhai;  Li, Xuehua;  Li, Renmin;  Zhao, Jianmin;  Wu, Huifeng;  Li, F (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Shandong, Peoples R China. fli@yic.ac.cn;  hfwu@yic.ac.cn
浏览  |  Adobe PDF(1104Kb)  |  收藏  |  浏览/下载:836/378  |  提交时间:2015/07/31
Polybrominated Diphenyl Ethers  Thyroid-hormone Receptors  Structural Requirements  Surface Waters  In-silico  Plasticizers  Complex  Air  Regression  Zebrafish  
The interaction between organic phosphate ester and p53: An integrated experimental and in silico approach 期刊论文
MARINE POLLUTION BULLETIN, 2014, 卷号: 85, 期号: 2, 页码: 516-521
作者:  Li, Fei;  Li, Renmin;  Yang, Xianhai;  You, Liping;  Zhao, Jianmin;  Wu, Huifeng;  Li, F (reprint author), Chinese Acad Sci, YICCAS, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai 264003, Peoples R China. fli@yic.ac.cn;  hfwu@yic.ac.cn
浏览  |  Adobe PDF(915Kb)  |  收藏  |  浏览/下载:616/228  |  提交时间:2015/07/31
Organophosphate Flame Retardants (Opfrs) P53  Docking  Quantitative Structure-activity Relationship (Qsar)  Binding Affinity  Multiple Linear Regression (Mlr)