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大数据挖掘和机器学习在毒理学中的应用 期刊论文
生态毒理学报, 2022, 卷号: 17, 期号: 1, 页码: 93-101
作者:  滕跃发;  王晓晴;  李斐;  吴惠丰;  吉成龙;  于进福
收藏  |  浏览/下载：18/0  |  提交时间：2024/01/26
数据挖掘  机器学习  结构-活性关系  AOP  计算毒理学  
Tetrabromobisphenol A induced reproductive endocrine-disrupting effects in mussel Mytilus galloprovincialis 期刊论文
JOURNAL OF HAZARDOUS MATERIALS, 2021, 卷号: 416, 页码: 9
作者:  Wang, Shuang;  Ji, Chenglong;  Li, Fei;  Zhan, Junfei;  Sun, Tao;  Tang, Jianhui;  Wu, Huifeng
浏览  |  Adobe PDF(4030Kb)  |  收藏  |  浏览/下载：533/216  |  提交时间：2021/10/21
Brominated flame retardants  Marine invertebrates  Endocrine disruptor  Steroids sulfonation  
Dose-dependent responses of metabolism and tissue injuries in clam Ruditapes philippinarum after subchronic exposure to cadmium 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2021, 卷号: 779, 页码: 11
作者:  Zhan, Junfei;  Wang, Shuang;  Li, Fei;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(2610Kb)  |  收藏  |  浏览/下载：548/279  |  提交时间：2021/10/20
Cadmium  Dose-response  Hormesis  Metabolomics  Ruditapes philippinarum  Tissue injuries  
Environmentally relevant concentrations of microplastics influence the locomotor activity of aquatic biota 期刊论文
JOURNAL OF HAZARDOUS MATERIALS, 2021, 卷号: 414, 页码: 10
作者:  Sun, Tao;  Zhan, Junfei;  Li, Fei;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(4268Kb)  |  收藏  |  浏览/下载：691/343  |  提交时间：2021/10/20
Microplastics  Aquatic biota  Locomotor activity  Environmentally relevant concentrations  Meta-analysis  
Integration of Computational Toxicology, Toxicogenomics Data Mining, and Omics Techniques to Unveil Toxicity Pathways 期刊论文
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2021, 卷号: 9, 期号: 11, 页码: 4130-4138
作者:  Wang, Xiaoqing;  Li, Fei;  Chen, Jingwen;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(3938Kb)  |  收藏  |  浏览/下载：710/291  |  提交时间：2021/05/22
Adverse outcome pathway (AOP)  Comparative toxicogenomics database (CTD)  Triphenyl phosphate (TPP)  Molecular dynamics (MD)  Transcriptome analyses  
Global characterization of dose-dependent effects of cadmium in clam Ruditapes philippinarum 期刊论文
ENVIRONMENTAL POLLUTION, 2021, 卷号: 273, 页码: 9
作者:  Zhan, Junfei;  Wang, Shuang;  Li, Fei;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(1425Kb)  |  收藏  |  浏览/下载：567/217  |  提交时间：2021/05/22
Benchmark dose  Cadmium  Dose-dependent effects  Ruditapes philippinarum  Transcriptomics  
Proteomic analysis revealed gender-specific responses of mussels (Mytilus galloprovincialis) to trichloropropyl phosphate (TCPP) exposure 期刊论文
ENVIRONMENTAL POLLUTION, 2020, 卷号: 267, 页码: 11
作者:  Zhong, Mingyu;  Wu, Huifeng;  Li, Fei;  Shan, Xiujuan;  Ji, Chenglong
浏览  |  Adobe PDF(3290Kb)  |  收藏  |  浏览/下载：519/189  |  提交时间：2021/06/07
Trichloropropyl phosphate (TCPP)  Mytilus galloprovincialis  Gender-specific effects  iTRAQ  Proteomics  
Transcriptomic, proteomic and metabolomic profiling unravel the mechanisms of hepatotoxicity pathway induced by triphenyl phosphate (TPP) 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 205, 页码: 9
作者:  Wang, Xiaoqing;  Li, Fei;  Liu, Jialin;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(6774Kb)  |  收藏  |  浏览/下载：385/53  |  提交时间：2021/06/21
Triphenyl phosphate (TPP)  Multi-omit approach  Hepatotoxicity  
Evaluation on the biomagnification or biodilution of trace metals in global marine food webs by meta-analysis 期刊论文
ENVIRONMENTAL POLLUTION, 2020, 卷号: 264, 页码: 11
作者:  Sun, Tao;  Wu, Huifeng;  Wang, Xiaoqing;  Ji, Chenglong;  Shan, Xiujuan;  Li, Fei
浏览  |  Adobe PDF(2296Kb)  |  收藏  |  浏览/下载：668/290  |  提交时间：2021/06/21
Trace metals  Marine food webs  Metal concentration  Trophic transfer  Marine environment  
Metal pollution and its biological effects in swimming crab Portunus trituberculatus by NMR-based metabolomics 期刊论文
MARINE POLLUTION BULLETIN, 2020, 卷号: 157, 页码: 6
作者:  Yu, Deliang;  Peng, Xiao;  Ji, Chenglong;  Li, Fei;  Wu, Huifeng
浏览  |  Adobe PDF(1413Kb)  |  收藏  |  浏览/下载：538/218  |  提交时间：2021/06/21
Metal pollution  Portunus trituberculatus  Biological effects  Metabolomics