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Integration of Computational Toxicology, Toxicogenomics Data Mining, and Omics Techniques to Unveil Toxicity Pathways 期刊论文
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2021, 卷号: 9, 期号: 11, 页码: 4130-4138
作者:  Wang, Xiaoqing;  Li, Fei;  Chen, Jingwen;  Ji, Chenglong;  Wu, Huifeng
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Adverse outcome pathway (AOP)  Comparative toxicogenomics database (CTD)  Triphenyl phosphate (TPP)  Molecular dynamics (MD)  Transcriptome analyses  
Transcriptomic, proteomic and metabolomic profiling unravel the mechanisms of hepatotoxicity pathway induced by triphenyl phosphate (TPP) 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 205, 页码: 9
作者:  Wang, Xiaoqing;  Li, Fei;  Liu, Jialin;  Ji, Chenglong;  Wu, Huifeng
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Triphenyl phosphate (TPP)  Multi-omit approach  Hepatotoxicity  
The critical factors affecting typical organophosphate flame retardants to mimetic biomembrane: An integrated in vitro and in silico study 期刊论文
CHEMOSPHERE, 2019, 卷号: 226, 页码: 159-165
作者:  Wang, XQ;  Meng, XJ;  Li, F;  Ding, JW;  Ji, CL;  Wu, HF
浏览  |  Adobe PDF(969Kb)  |  收藏  |  浏览/下载：481/206  |  提交时间：2020/07/08
Organophosphate flame retardants (OPFRs)  Quantitative structure-activity relationship (QSAR)  Mimetic biomembrane  Electrochemical impedance spectroscopy (EIS)  Partial least squares (PLS)  
Self-assembly of nanoparticles by human serum albumin and photosensitizer for targeted near-infrared emission fluorescence imaging and effective phototherapy of cancer 期刊论文
JOURNAL OF MATERIALS CHEMISTRY B, 2019, 卷号: 7, 期号: 7, 页码: 1149-1159
作者:  Huang, Y;  He, N;  Wang, YQ;  Shen, DZ;  Kang, Q;  Zhao, RF;  Chen, LX
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LUMINESCENT GOLD NANOPARTICLES  INDOCYANINE GREEN  PHOTODYNAMIC THERAPY  RENAL CLEARANCE  IN-VITRO  ONE-POT  NANOMATERIALS  DECOMPOSITION  NANOMEDICINE  THERANOSTICS  
Toxicological effects of tris(2-chloropropyl) phosphate in human hepatic cells 期刊论文
CHEMOSPHERE, 2017, 卷号: 187, 页码: 88-96
作者:  Li, Fei;  Wang, Li;  Ji, Chenglong;  Wu, Huifeng;  Zhao, Jianmin;  Tang, Jianhui;  Wu, Huifeng(Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai 264003, Peoples R China)
收藏  |  浏览/下载：408/0  |  提交时间：2018/01/10
Tris(2-chloropropyl) Phosphate (Tcpp)  L02 Cells  Cell Apoptosis  Ros  Metabolomics  Proteomics  
典型持久性有机污染物与抑癌基因相互作用的分子模拟与验证 期刊论文
科学通报, 2015, 卷号: 60, 期号: 19, 页码: 1804-1809
作者:  吴惠丰;  曹璐璐;  李斐;  李雪花;  赵建民
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持久性有机污染物  P53  2  分子模拟  2'  光谱法  4  4'-四溴联苯醚(Bde-47)  
Multiple biomarkers of the cytotoxicity induced by BDE-47 in human embryonic kidney cells 期刊论文
CHEMOSPHERE, 2015, 卷号: 126, 页码: 32-39
作者:  Wu, Huifeng;  Cao, Lulu;  Li, Fei;  Lian, Peiwen;  Zhao, Jianmin;  Li, F (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai 264003, Shandong, Peoples R China. fli@yic.ac.cn
浏览  |  Adobe PDF(765Kb)  |  收藏  |  浏览/下载：860/375  |  提交时间：2015/07/31
Bde-47  Hek293 Cells  Cytotoxicity  Cell Apoptosis  Ros  Metabolomics  
Affinities of organophosphate flame retardants to tumor suppressor gene p53: An integrated in vitro and in silico study 期刊论文
TOXICOLOGY LETTERS, 2015, 卷号: 232, 期号: 2, 页码: 533-541
作者:  Li, Fei;  Cao, Lulu;  Li, Xuehua;  Li, Na;  Wang, Zijian;  Wu, Huifeng;  Wu, HF (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Shandong, Peoples R China. hfwu@yic.ac.cn
浏览  |  Adobe PDF(2093Kb)  |  收藏  |  浏览/下载：800/288  |  提交时间：2015/07/31
Organophosphate Flame Retardants (Opfrs)  P53  Docking  Quantitative Structure-activity Relationship (Qsar)  Binding Affinity  Partial Least Squares (Pls)  
BDE-47对人胚肾细胞HEK293的毒理效应及作用机制 期刊论文
生态毒理学报, 2015, 卷号: ., 期号: 2, 页码: 236-242
作者:  曹璐璐;  李斐;  吴惠丰;  赵建民
浏览  |  Adobe PDF(304Kb)  |  收藏  |  浏览/下载：383/160  |  提交时间：2021/06/16
2,2’,4,4’-四溴联苯醚（BDE-47）  人胚肾细胞  细胞凋亡  氧化损伤  p53  Bax  
Upconversion Fluorescence-SERS Dual-Mode Tags for Cellular and in Vivo Imaging 期刊论文
ACS APPLIED MATERIALS & INTERFACES, 2014, 卷号: 6, 期号: 7, 页码: 5152-5160
作者:  Niu, Xiaojuan;  Chen, Haiyan;  Wang, Yunqing;  Wang, Wenhai;  Sun, Xiuyan;  Chen, Lingxin;  Wang, YQ (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China. yqwang@yic.ac.cn;  lxchen@yic.ac.cn
浏览  |  Adobe PDF(7539Kb)  |  收藏  |  浏览/下载：927/393  |  提交时间：2015/07/31
Upconversion Nanoparticles  Silver Nanoparticles  Fluorescence  Surface-enhanced Raman Scattering (Sers)  Dual-mode Imaging