Synthesis and antioxidant property of novel 1,2,3-triazole-linked starch derivatives via 'click chemistry'

doi:10.1016/j.ijbiomac.2015.10.007

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	Synthesis and antioxidant property of novel 1,2,3-triazole-linked starch derivatives via 'click chemistry'
	Tan, WQ; Li, Q ; Li, WC ; Dong, F; Guo, ZY; Guo, ZY (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China. zhanyongguo@hotmail.com
发表期刊	INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
ISSN	0141-8130
	2016
卷号	82 页码:404-410
关键词	Starch Derivatives Click Chemistry Antioxidant Activity
DOI	10.1016/j.ijbiomac.2015.10.007
产权排序	[Tan, Wenqiang; Li, Qing; Li, Wancong; Dong, Fang; Guo, Zhanyong] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China; [Tan, Wenqiang; Li, Wancong] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
作者部门	海岸带生物学与生物资源利用所重点实验室
英文摘要	Based on the copper (I) catalyzed Huisgen azide-alkyne cycloaddition (click chemistry), the novel synthesis of a variety of 1,2,3-triazole-linked starch derivatives was developed, including 6-hydroxymethyltriazole-6-deoxy starch (HMTST), 6-hydroxyethyltriazole-6-deoxy starch (HETST), 6-hydroxypropyltriazole-6-deoxy starch (HPTST), and 6-hydroxybutyltriazole-6-deoxy starch (HBTST). Their antioxidant properties against hydroxyl-radical, DPPH-radical, and superoxide-radical were evaluated in vitro, respectively. The antioxidant activity of the obtained novel amphiprotic starch derivatives via 'click reaction' exhibited remarkable improvement over starch. And the scavenging effect indices of most of the products were higher than 60% at 1.6 mg/mL against hydroxyl-radical and DPPH-radical. Moreover, the scavenging effect of the products against superoxide-radical attained 90% above at 0.1 mg/mL. Generally, the antioxidant activity decreased in the order: HBTST > HPTST > HETST >HMTST > starch. Furthermore, the order of their antioxidant activity was consistent with the electron-donating ability of different substituted groups of the 1,2,3-triazoles. The substituted groups with stronger electron supplying capacity provided more electrons to the various radicals, which relatively enhanced the capacity for scavenging free radicals. (c) 2015 Elsevier B.V. All rights reserved.
文章类型	Article
资助机构	Science and Technology Service Network Initiative(KFJ-EW-STS-060) ; National Natural Science Foundation of China(41206152) ; Science and Technology Project of Weihai(2012GNS004) ; Taishan Scholar Program of Shandong Province
收录类别	SCI
语种	英语
关键词[WOS]	BIOLOGICAL EVALUATION ; ANTIBACTERIAL ; CHITOSAN ; AMYLASE ; CYTOTOXICITY ; SILATRANES ; SILYLATION ; INULIN ; AGENTS ; CELLS
研究领域[WOS]	Biochemistry & Molecular Biology ; Chemistry ; Polymer Science
WOS记录号	WOS:000367425100052
引用统计	被引频次：71[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.yic.ac.cn/handle/133337/9307
专题	海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室中国科学院海岸带环境过程与生态修复重点实验室_污染过程与控制实验室海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心
通讯作者	Guo, ZY (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China. zhanyongguo@hotmail.com
作者单位	1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat 2.Univ Chinese Acad Sci
推荐引用方式 GB/T 7714	Tan, WQ,Li, Q,Li, WC,et al. Synthesis and antioxidant property of novel 1,2,3-triazole-linked starch derivatives via 'click chemistry'[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2016,82:404-410.
APA	Tan, WQ,Li, Q,Li, WC,Dong, F,Guo, ZY,&Guo, ZY .(2016).Synthesis and antioxidant property of novel 1,2,3-triazole-linked starch derivatives via 'click chemistry'.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,82,404-410.
MLA	Tan, WQ,et al."Synthesis and antioxidant property of novel 1,2,3-triazole-linked starch derivatives via 'click chemistry'".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 82(2016):404-410.

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