Hypolipidemic and antioxidant properties of a polysaccharide fraction from Enteromorpha prolifera
Tang, Zhihong1; Gao, Hongwei2; Wang, Shuai1; Wen, Shaohong1; Qin, Song3
发表期刊INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
2013-07-01
卷号58页码:186-189
关键词Enteromorpha Prolifera Polysaccharides Hypolipidemic Antioxidant
英文摘要A polysaccharide fraction (EPF2) was obtained from the crude polysaccharides of Enteromorpha prolifera by a series isolation procedure. Monosaccharide components analysis indicated that EPF2 was composed of rhamnose, xylose, mannose, galactose and glucose in a molar ratio of 3.64:1.08:0.21:0.75:0.27. Hypolipidemic and antioxidant properties of EPF2 were investigated. The results showed that the hypolipidemic effect of EPF2 was in a concentration-dependent fashion and the prior oral administration of EPF2 (300 mg/kg body weight) exhibited considerable effect which could bear comparison with that of simvastatin. Moreover, administration of EPF2 could significantly enhance the activities of endogenous antioxidant enzymes and lowered the content of maleic dialdehyde (MDA) in serum. The results suggested that EPF2 had a high hypolipidemic activity and this activity might be attributed to its antioxidant potential. (C) 2013 Elsevier B.V. All rights reserved.
文章类型Article
收录类别SCI
语种英语
关键词[WOS]LYCIUM-BARBARUM POLYSACCHARIDES ; OXIDATIVE STRESS ; LIPID-PEROXIDATION ; GANODERMA-LUCIDUM ; IN-VIVO ; RATS ; CHOLESTEROL ; METABOLISM ; EXTRACTS ; LEAVES
研究领域[WOS]Biochemistry & Molecular Biology
WOS记录号WOS:000320746200027
引用统计
被引频次:79[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cn/handle/133337/9039
专题海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室
作者单位1.Yantai Univ, Coll Life Sci, Yantai 264005, Shandong, Peoples R China
2.Beijing Inst Transfus Med, Beijing 100850, Peoples R China
3.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Jinan 264003, Shandong, Peoples R China
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Tang, Zhihong,Gao, Hongwei,Wang, Shuai,et al. Hypolipidemic and antioxidant properties of a polysaccharide fraction from Enteromorpha prolifera[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2013,58:186-189.
APA Tang, Zhihong,Gao, Hongwei,Wang, Shuai,Wen, Shaohong,&Qin, Song.(2013).Hypolipidemic and antioxidant properties of a polysaccharide fraction from Enteromorpha prolifera.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,58,186-189.
MLA Tang, Zhihong,et al."Hypolipidemic and antioxidant properties of a polysaccharide fraction from Enteromorpha prolifera".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 58(2013):186-189.
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