YIC-IR  > 中科院海岸带环境过程与生态修复重点实验室
Fluorescent probes for hydrogen sulfide detection and bioimaging
Yu, Fabiao1; Han, Xiaoyue1,2; Chen, Lingxin1; Chen, LX (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol Shandong, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China. lxchen@yic.ac.cn
2014-10-21
Source PublicationCHEMICAL COMMUNICATIONS
ISSN1359-7345
Volume50Issue:82Pages:12234-12249
Contribution Rank[Yu, Fabiao; Han, Xiaoyue; Chen, Lingxin] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol Shandong, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China; [Han, Xiaoyue] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
AbstractIn comparison with other biological detection technologies, fluorescence bioimaging technology has become a powerful supporting tool for intracellular detection, and can provide attractive facilities for investigating physiological and pathological processes of interest with high spatial and temporal resolution, less invasiveness, and a rapid response. Due to the versatile roles of hydrogen sulfide (H2S) in cellular signal transduction and intracellular redox status regulation, fluorescent probes for the detection of this third signalling gasotransmitter have rapidly increased in number in recent years. These probes can offer powerful means to investigate the physiological actions of H2S in its native environments without disturbing its endogenous distribution. In this feature article, we address the synthesis and design strategies for the development of fluorescent probes for H2S based on the reaction type between H2S and the probes. Moreover, we also highlight fluorescent probes for other reactive sulfur species, such as sulfane sulfurs and SO2 derivatives.; In comparison with other biological detection technologies, fluorescence bioimaging technology has become a powerful supporting tool for intracellular detection, and can provide attractive facilities for investigating physiological and pathological processes of interest with high spatial and temporal resolution, less invasiveness, and a rapid response. Due to the versatile roles of hydrogen sulfide (H2S) in cellular signal transduction and intracellular redox status regulation, fluorescent probes for the detection of this third signalling gasotransmitter have rapidly increased in number in recent years. These probes can offer powerful means to investigate the physiological actions of H2S in its native environments without disturbing its endogenous distribution. In this feature article, we address the synthesis and design strategies for the development of fluorescent probes for H2S based on the reaction type between H2S and the probes. Moreover, we also highlight fluorescent probes for other reactive sulfur species, such as sulfane sulfurs and SO2 derivatives.
KeywordTurn-on Probe Living Cells Selective Detection Hypobromous Acid Oxidative Stress High-sensitivity Aqueous-solution So2 Derivatives H2s Production Redox Cycle
Department中科院海岸带环境过程与生态修复重点实验室
Subject AreaChemistry, Multidisciplinary
DOI10.1039/c4cc03312d
Funding OrganizationChemistry
Indexed BySCI
WOS KeywordTURN-ON PROBE ; LIVING CELLS ; SELECTIVE DETECTION ; HYPOBROMOUS ACID ; OXIDATIVE STRESS ; HIGH-SENSITIVITY ; AQUEOUS-SOLUTION ; SO2 DERIVATIVES ; H2S PRODUCTION ; REDOX CYCLE
SubtypeArticle
Language英语
WOS Research AreaChemistry
WOS IDWOS:000342887100002
Citation statistics
Document Type期刊论文
Identifierhttp://ir.yic.ac.cn/handle/133337/8700
Collection中科院海岸带环境过程与生态修复重点实验室
Corresponding AuthorChen, LX (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol Shandong, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China. lxchen@yic.ac.cn
Affiliation1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol Shandong, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
First Author AffilicationYantai Institute of Coastal Zone Research, Chinese Academy of Sciences
Recommended Citation
GB/T 7714
Yu, Fabiao,Han, Xiaoyue,Chen, Lingxin,et al. Fluorescent probes for hydrogen sulfide detection and bioimaging[J]. CHEMICAL COMMUNICATIONS,2014,50(82):12234-12249.
APA Yu, Fabiao,Han, Xiaoyue,Chen, Lingxin,&Chen, LX .(2014).Fluorescent probes for hydrogen sulfide detection and bioimaging.CHEMICAL COMMUNICATIONS,50(82),12234-12249.
MLA Yu, Fabiao,et al."Fluorescent probes for hydrogen sulfide detection and bioimaging".CHEMICAL COMMUNICATIONS 50.82(2014):12234-12249.
Files in This Item: Download All
File Name/Size DocType Version Access License
Fluorescent probes f(2939KB) 开放获取CC BY-NC-SAView Download
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Yu, Fabiao]'s Articles
[Han, Xiaoyue]'s Articles
[Chen, Lingxin]'s Articles
Baidu academic
Similar articles in Baidu academic
[Yu, Fabiao]'s Articles
[Han, Xiaoyue]'s Articles
[Chen, Lingxin]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Yu, Fabiao]'s Articles
[Han, Xiaoyue]'s Articles
[Chen, Lingxin]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: Fluorescent probes for hydrogen sulfide detection and bioimaging.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.