Institutional Repository of Key Laboratory of Coastal Zone Environmental Processes, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences (KLCEP)
Fluorescent probes for hydrogen sulfide detection and bioimaging | |
Yu, Fabiao1; Han, Xiaoyue1,2; Chen, Lingxin1; Chen, LX (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol Shandong, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China. lxchen@yic.ac.cn | |
发表期刊 | CHEMICAL COMMUNICATIONS |
ISSN | 1359-7345 |
2014-10-21 | |
卷号 | 50期号:82页码:12234-12249 |
关键词 | Turn-on Probe Living Cells Selective Detection Hypobromous Acid Oxidative Stress High-sensitivity Aqueous-solution So2 Derivatives H2s Production Redox Cycle |
DOI | 10.1039/c4cc03312d |
产权排序 | [Yu, Fabiao; Han, Xiaoyue; Chen, Lingxin] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol Shandong, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China; [Han, Xiaoyue] Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
作者部门 | 中科院海岸带环境过程与生态修复重点实验室 |
英文摘要 | In comparison with other biological detection technologies, fluorescence bioimaging technology has become a powerful supporting tool for intracellular detection, and can provide attractive facilities for investigating physiological and pathological processes of interest with high spatial and temporal resolution, less invasiveness, and a rapid response. Due to the versatile roles of hydrogen sulfide (H2S) in cellular signal transduction and intracellular redox status regulation, fluorescent probes for the detection of this third signalling gasotransmitter have rapidly increased in number in recent years. These probes can offer powerful means to investigate the physiological actions of H2S in its native environments without disturbing its endogenous distribution. In this feature article, we address the synthesis and design strategies for the development of fluorescent probes for H2S based on the reaction type between H2S and the probes. Moreover, we also highlight fluorescent probes for other reactive sulfur species, such as sulfane sulfurs and SO2 derivatives.; In comparison with other biological detection technologies, fluorescence bioimaging technology has become a powerful supporting tool for intracellular detection, and can provide attractive facilities for investigating physiological and pathological processes of interest with high spatial and temporal resolution, less invasiveness, and a rapid response. Due to the versatile roles of hydrogen sulfide (H2S) in cellular signal transduction and intracellular redox status regulation, fluorescent probes for the detection of this third signalling gasotransmitter have rapidly increased in number in recent years. These probes can offer powerful means to investigate the physiological actions of H2S in its native environments without disturbing its endogenous distribution. In this feature article, we address the synthesis and design strategies for the development of fluorescent probes for H2S based on the reaction type between H2S and the probes. Moreover, we also highlight fluorescent probes for other reactive sulfur species, such as sulfane sulfurs and SO2 derivatives. |
文章类型 | Article |
资助机构 | Chemistry |
收录类别 | SCI |
语种 | 英语 |
关键词[WOS] | TURN-ON PROBE ; LIVING CELLS ; SELECTIVE DETECTION ; HYPOBROMOUS ACID ; OXIDATIVE STRESS ; HIGH-SENSITIVITY ; AQUEOUS-SOLUTION ; SO2 DERIVATIVES ; H2S PRODUCTION ; REDOX CYCLE |
研究领域[WOS] | Chemistry |
WOS记录号 | WOS:000342887100002 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.yic.ac.cn/handle/133337/8700 |
专题 | 中国科学院海岸带环境过程与生态修复重点实验室 |
通讯作者 | Chen, LX (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol Shandong, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China. lxchen@yic.ac.cn |
作者单位 | 1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol Shandong, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
推荐引用方式 GB/T 7714 | Yu, Fabiao,Han, Xiaoyue,Chen, Lingxin,et al. Fluorescent probes for hydrogen sulfide detection and bioimaging[J]. CHEMICAL COMMUNICATIONS,2014,50(82):12234-12249. |
APA | Yu, Fabiao,Han, Xiaoyue,Chen, Lingxin,&Chen, LX .(2014).Fluorescent probes for hydrogen sulfide detection and bioimaging.CHEMICAL COMMUNICATIONS,50(82),12234-12249. |
MLA | Yu, Fabiao,et al."Fluorescent probes for hydrogen sulfide detection and bioimaging".CHEMICAL COMMUNICATIONS 50.82(2014):12234-12249. |
条目包含的文件 | 下载所有文件 | |||||
文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
Fluorescent probes f(2939KB) | 开放获取 | CC BY-NC-SA | 浏览 下载 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论