Fluorescent probes for hydrogen sulfide detection and bioimaging
Yu, Fabiao1; Han, Xiaoyue1,2; Chen, Lingxin1; Chen, LX (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol Shandong, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China. lxchen@yic.ac.cn
发表期刊CHEMICAL COMMUNICATIONS
ISSN1359-7345
2014-10-21
卷号50期号:82页码:12234-12249
关键词Turn-on Probe Living Cells Selective Detection Hypobromous Acid Oxidative Stress High-sensitivity Aqueous-solution So2 Derivatives H2s Production Redox Cycle
DOI10.1039/c4cc03312d
产权排序[Yu, Fabiao; Han, Xiaoyue; Chen, Lingxin] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol Shandong, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China; [Han, Xiaoyue] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
作者部门中科院海岸带环境过程与生态修复重点实验室
英文摘要In comparison with other biological detection technologies, fluorescence bioimaging technology has become a powerful supporting tool for intracellular detection, and can provide attractive facilities for investigating physiological and pathological processes of interest with high spatial and temporal resolution, less invasiveness, and a rapid response. Due to the versatile roles of hydrogen sulfide (H2S) in cellular signal transduction and intracellular redox status regulation, fluorescent probes for the detection of this third signalling gasotransmitter have rapidly increased in number in recent years. These probes can offer powerful means to investigate the physiological actions of H2S in its native environments without disturbing its endogenous distribution. In this feature article, we address the synthesis and design strategies for the development of fluorescent probes for H2S based on the reaction type between H2S and the probes. Moreover, we also highlight fluorescent probes for other reactive sulfur species, such as sulfane sulfurs and SO2 derivatives.; In comparison with other biological detection technologies, fluorescence bioimaging technology has become a powerful supporting tool for intracellular detection, and can provide attractive facilities for investigating physiological and pathological processes of interest with high spatial and temporal resolution, less invasiveness, and a rapid response. Due to the versatile roles of hydrogen sulfide (H2S) in cellular signal transduction and intracellular redox status regulation, fluorescent probes for the detection of this third signalling gasotransmitter have rapidly increased in number in recent years. These probes can offer powerful means to investigate the physiological actions of H2S in its native environments without disturbing its endogenous distribution. In this feature article, we address the synthesis and design strategies for the development of fluorescent probes for H2S based on the reaction type between H2S and the probes. Moreover, we also highlight fluorescent probes for other reactive sulfur species, such as sulfane sulfurs and SO2 derivatives.
文章类型Article
资助机构Chemistry
收录类别SCI
语种英语
关键词[WOS]TURN-ON PROBE ; LIVING CELLS ; SELECTIVE DETECTION ; HYPOBROMOUS ACID ; OXIDATIVE STRESS ; HIGH-SENSITIVITY ; AQUEOUS-SOLUTION ; SO2 DERIVATIVES ; H2S PRODUCTION ; REDOX CYCLE
研究领域[WOS]Chemistry
WOS记录号WOS:000342887100002
引用统计
被引频次:362[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cn/handle/133337/8700
专题中国科学院海岸带环境过程与生态修复重点实验室
通讯作者Chen, LX (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol Shandong, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China. lxchen@yic.ac.cn
作者单位1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol Shandong, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
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GB/T 7714
Yu, Fabiao,Han, Xiaoyue,Chen, Lingxin,et al. Fluorescent probes for hydrogen sulfide detection and bioimaging[J]. CHEMICAL COMMUNICATIONS,2014,50(82):12234-12249.
APA Yu, Fabiao,Han, Xiaoyue,Chen, Lingxin,&Chen, LX .(2014).Fluorescent probes for hydrogen sulfide detection and bioimaging.CHEMICAL COMMUNICATIONS,50(82),12234-12249.
MLA Yu, Fabiao,et al."Fluorescent probes for hydrogen sulfide detection and bioimaging".CHEMICAL COMMUNICATIONS 50.82(2014):12234-12249.
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