Development of a Biomedical Micro/Nano Robot for Drug Delivery

doi:10.1166/jnn.2015.9643

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	Development of a Biomedical Micro/Nano Robot for Drug Delivery
	Zhang, Zhenhai; Li, Zhifei; Yu, Wei; Li, Kejie; Xie, Zhihong; Xie, ZH (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Shandong, Peoples R China.
发表期刊	JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
ISSN	1533-4880
	2015-04
卷号	15 期号:4 页码:3126-3129
关键词	Micro/nano Robot Bacterial Flagellar Motor Liposome Antibody Drug Delivery System
DOI	10.1166/jnn.2015.9643
产权排序	[Zhang, Zhenhai; Li, Kejie] Beijing Inst Technol, Sch Mechatron Engn, Beijing 100081, Peoples R China; [Li, Zhifei] Peking Univ, Dept Gen Surg, Hosp 3, Beijing 100191, Peoples R China; [Yu, Wei] Shanghai Second Polytech Univ, Sch Urban Dev & Environm Engn, Shanghai 201209, Peoples R China; [Xie, Zhihong] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Shandong, Peoples R China
作者部门	海岸带生物学与生物资源利用所重点实验室
英文摘要	Flagellated bacteria have been utilized as potential swimming micro-robotic bodies for propulsion of spherical liposome by attaching several bacteria on their surface. Liposome as a drug delivery vehicle can contain biologically active compounds. In this work, the antibody binding technique is developed to attach bacteria to liposome's surface. Consequently, the stochastic effect of bacterial propulsion of liposome is investigated analytically and experimentally. It is shown that the mobility of liposome with bacteria was higher than that of liposome without bacteria. Experimental data matches well with statistical calculation.
文章类型	期刊论文
资助机构	Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
收录类别	SCI
语种	英语
关键词[WOS]	FLAGELLA ; MOTOR
研究领域[WOS]	National Natural Science Foundation of China [61273346, 31370108, 51106093, 50876058] ; Hundred Talents Program of Chinese Academy of Sciences [1103000003] ; Key Projects in the Yantai Science and Technology Pillar Program [2013JH021] ; National Defense Major Fundamental Research Program of China [C x x 20110003] ; National Defense Key Fundamental Research Program of China [A x x 20110005, A x x 20132010] ; Specialized Research Fund for the Doctoral Program of Higher Education [20121101120009] ; Scientific Research Foundation for the Returned Overseas Chinese Scholars, Excellent Young Scholars Research Fund of Beijing Institute of Technology [2012YG0203] ; Program for the Fundamental Research of Beijing Institute of Technology [2013CX04031, 2011CX02023, 2014CX x x x x] ; Program of Introducing Talents of Discipline to University, China [B08043]
WOS记录号	WOS:000347435100080
引用统计	被引频次：7[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.yic.ac.cn/handle/133337/8510
专题	海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室
通讯作者	Xie, ZH (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Shandong, Peoples R China.
推荐引用方式 GB/T 7714	Zhang, Zhenhai,Li, Zhifei,Yu, Wei,et al. Development of a Biomedical Micro/Nano Robot for Drug Delivery[J]. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,2015,15(4):3126-3129.
APA	Zhang, Zhenhai,Li, Zhifei,Yu, Wei,Li, Kejie,Xie, Zhihong,&Xie, ZH .(2015).Development of a Biomedical Micro/Nano Robot for Drug Delivery.JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,15(4),3126-3129.
MLA	Zhang, Zhenhai,et al."Development of a Biomedical Micro/Nano Robot for Drug Delivery".JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY 15.4(2015):3126-3129.