YIC-IR  > 环境化学实验室
Primary-ion-conditioned polymeric membrane electrodes for sensitive detection of polyions
Wang, Xuewei1,2; Ding, Jiawang1; Song, Wenjing1,2; Xie, Kang1,3; Qin, Wei1
2012-01-03
发表期刊SENSORS AND ACTUATORS B-CHEMICAL
ISSN0925-4005
卷号161期号:1页码:1119-1123
产权排序[Wang, Xuewei; Ding, Jiawang; Song, Wenjing; Xie, Kang; Qin, Wei] Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China; [Wang, Xuewei; Song, Wenjing] Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China; [Xie, Kang] Yantai Univ, Coll Chem & Biol, Yantai 264005, Peoples R China
摘要A novel operation mode for development of sensitive and renewable polymeric membrane polyion-sensitive electrodes has been explored in this paper. In contrast to the traditional polyion sensors which are conditioned with highly discriminated ions, the proposed polycation-sensitive membrane electrode with dinonylnaphthalene sulfonate as the ion-exchanger is conditioned with the primary ion (protamine), and activated with the discriminated ion (Na+) before measurement. Using this protocol, the membrane with protamine in the membrane bulk but with discriminated ions rich at the membrane outer surface can be prepared. The protamine inside the membrane efficiently suppresses the fluxes of protamine from the sample-membrane interface into the membrane bulk, thus decreasing the detection limit toward protamine by one order of magnitude. With the reproducible protamine fluxes obtained by the conditioning and activation steps, the protamine-sensitive electrode could be reused without significant signal deterioration. Titrimetric analysis of heparin with this novel technique has been demonstrated. The proposed polyion sensing platform offers much promise in the detection of polyions as well as in other polyion-involved bioanalyses.; A novel operation mode for development of sensitive and renewable polymeric membrane polyion-sensitive electrodes has been explored in this paper. In contrast to the traditional polyion sensors which are conditioned with highly discriminated ions, the proposed polycation-sensitive membrane electrode with dinonylnaphthalene sulfonate as the ion-exchanger is conditioned with the primary ion (protamine), and activated with the discriminated ion (Na+) before measurement. Using this protocol, the membrane with protamine in the membrane bulk but with discriminated ions rich at the membrane outer surface can be prepared. The protamine inside the membrane efficiently suppresses the fluxes of protamine from the sample-membrane interface into the membrane bulk, thus decreasing the detection limit toward protamine by one order of magnitude. With the reproducible protamine fluxes obtained by the conditioning and activation steps, the protamine-sensitive electrode could be reused without significant signal deterioration. Titrimetric analysis of heparin with this novel technique has been demonstrated. The proposed polyion sensing platform offers much promise in the detection of polyions as well as in other polyion-involved bioanalyses. (c) 2011 Elsevier B.V. All rights reserved.
通讯作者Qin, W (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res, Chunhui Rd 17, Yantai 264003, Peoples R China. wqin@yic.ac.cn
关键词Potentiometry Ion-selective Electrode Polyion Protamine Heparin Electrode Conditioning
作者部门环境化学实验室 
学科领域Chemistry ; Electrochemistry ; Instruments & Instrumentation
项目资助者National Natural Science Foundation of China[41176081]; Outstanding Youth Natural Science Foundation of Shandong Province[JQ200814]; Taishan Scholar Program of Shandong Province[TS20081159]
URL查看原文
收录类别SCI
关键词[WOS]RESPONSE CHARACTERISTICS ; ELECTROCHEMICAL ASSAY ; REVERSIBLE DETECTION ; HEPARIN ; PROTAMINE ; SENSORS ; POTENTIOMETRY ; POLYANIONS ; BINDING
文章类型Article
语种英语
WOS研究方向Chemistry ; Electrochemistry ; Instruments & Instrumentation
WOS记录号WOS:000301549400153
引用统计
文献类型期刊论文
条目标识符http://ir.yic.ac.cn/handle/133337/5532
专题环境化学实验室
作者单位1.Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China
2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
3.Yantai Univ, Coll Chem & Biol, Yantai 264005, Peoples R China
推荐引用方式
GB/T 7714
Wang, Xuewei,Ding, Jiawang,Song, Wenjing,et al. Primary-ion-conditioned polymeric membrane electrodes for sensitive detection of polyions[J]. SENSORS AND ACTUATORS B-CHEMICAL,2012,161(1):1119-1123.
APA Wang, Xuewei,Ding, Jiawang,Song, Wenjing,Xie, Kang,&Qin, Wei.(2012).Primary-ion-conditioned polymeric membrane electrodes for sensitive detection of polyions.SENSORS AND ACTUATORS B-CHEMICAL,161(1),1119-1123.
MLA Wang, Xuewei,et al."Primary-ion-conditioned polymeric membrane electrodes for sensitive detection of polyions".SENSORS AND ACTUATORS B-CHEMICAL 161.1(2012):1119-1123.
条目包含的文件 下载所有文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
Primary-ion-conditio(229KB) 开放获取--浏览 下载
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Wang, Xuewei]的文章
[Ding, Jiawang]的文章
[Song, Wenjing]的文章
百度学术
百度学术中相似的文章
[Wang, Xuewei]的文章
[Ding, Jiawang]的文章
[Song, Wenjing]的文章
必应学术
必应学术中相似的文章
[Wang, Xuewei]的文章
[Ding, Jiawang]的文章
[Song, Wenjing]的文章
相关权益政策
暂无数据
收藏/分享
文件名: Primary-ion-conditioned polymeric membrane electrodes for sensitive detection of polyions.pdf
格式: Adobe PDF
此文件暂不支持浏览
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。