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题名:
Potentiometric sensor for sensitive and selective detection of heparin
作者: Chen, Yan1,2; Liang, Rong Ning1; Wei Qin(秦伟)1
刊名: CHINESE CHEMICAL LETTERS
ISSN号: 1001-8417
出版日期: 2012-02-01
卷号: 23, 期号:2, 页码:233-236
关键词: Potentiometry ; Sensing element ; Heparin ; Protamine ; Polyion sensor
学科分类: Chemistry
产权排序: [Chen, Yan; Liang, Rong Ning; Qin, Wei] Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China; [Chen, Yan] Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
通讯作者: Qin, W (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China. wqin@yic.ac.cn
作者部门: 环境化学实验室 
中文摘要: A polymeric membrane ion-selective electrode for determination of heparin is described in this paper. Protamine is incorporated into the organic membrane phase and functions as sensing element for selective recognition of heparin. The proposed membrane electrode exhibits high selectivity for heparin over lipophilic anions such as thiocyanide and salicylate. The potentiometric response to the concentration of heparin is linear in the range of 0.01-0.4 U/mL and a lower detection limit of 0.005 U/mL can be achieved.
英文摘要: A polymeric membrane ion-selective electrode for determination of heparin is described in this paper. Protamine is incorporated into the organic membrane phase and functions as sensing element for selective recognition of heparin. The proposed membrane electrode exhibits high selectivity for heparin over lipophilic anions such as thiocyanide and salicylate. The potentiometric response to the concentration of heparin is linear in the range of 0.01-0.4 U/mL and a lower detection limit of 0.005 U/mL can be achieved. (C) 2011 Wei Qin. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
研究领域[WOS]: Chemistry
关键词[WOS]: MEMBRANE-ELECTRODE ; BIOANALYTICAL APPLICATIONS ; ELECTROCHEMICAL SENSOR
文章类型: Article
收录类别: SCI
原文出处: 查看原文
语种: 英语
WOS记录号: WOS:000299917200028
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.yic.ac.cn/handle/133337/5528
Appears in Collections:环境化学实验室_期刊论文

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作者单位: 1.Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China
2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China

Recommended Citation:
Chen, Yan,Liang, Rong Ning,Qin, Wei. Potentiometric sensor for sensitive and selective detection of heparin[J]. CHINESE CHEMICAL LETTERS,2012,23(2):233-236.
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